Receptors, tnf-related apoptosis-inducing ligand

International Journal of Gynecological Cancer, 2000
Apoptosis is an intrinsic and fundamental biologic process that plays a critical role in the normal development of multicellular organisms and in the maintainance of tissue homeostasis. Some of the well known regulators of apoptosis are cytokines of the tumor necrosis factor (TNF) ligand family, such as Fas ligand (Fas L) and TNF, which induce ...
H. S., Ryu +5 more
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JCR: Journal of Clinical Rheumatology, 2019
Objectives Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) belongs to the tumor necrosis factor (TNF) superfamily and is reported to play a role in autoimmune diseases. In this study, we aimed to measure serum TRAIL receptor 1 (TRAIL-R1) concentration and assess any phenotypic relationship in patients with ...
Yazici, AYTEN +5 more
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Apoptosis, 2002
TNF-related apoptosis-inducing ligand (TRAIL/APO-2L) is a typical member of the TNF ligand family that induces apoptosis by activating the death receptors TRAIL-R1 and TRAIL-R2. TRAIL has attracted great attention in recent years as a promising anti cancer reagent because recombinant soluble TRAIL derivatives induce apoptosis in a broad range of tumor ...
H, Wajant, K, Pfizenmaier, P, Scheurich
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Analysis of TNF-related apoptosis-inducing ligand and receptors and implications in thymus biology and myasthenia gravis

Neuromuscular Disorders, 2017
Myasthenia Gravis is an autoantibody-mediated, neuromuscular junction disease, and is usually associated with thymic abnormalities presented as thymic tumors (~10%) or hyperplastic thymus (~65%). The exact role of thymus in Myasthenia Gravis development is not clear, yet many patients benefit from thymectomy.
Irem, Kanatli +4 more
openaire +2 more sources

trail
tnf-related apoptosis-inducing ligand
apoptosis regulatory proteins

medicine
membrane glycoproteins
receptors, tumor necrosis factor

animals
male
female