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Efficacy of lenvatinib combined with sintilimab and transcatheter arterial chemoembolization in conversion therapy for unresectable hepatocellular carcinoma. [PDF]
Long J, Zheng J, Chen S, Ou P, Lu X.
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Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart
Circulation, 1996Background Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine that produces negative inotropic effects in the heart. Recently, elevated levels of TNF-α have been reported in patients with advanced congestive heart failure.
Guillermo Torre-Amione, Douglas L. Mann
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The Tumor Necrosis Factor Ligand and Receptor Families
New England Journal of Medicine, 1996Tumor necrosis factor (TNF) and lymphotoxin-α were isolated more than 10 years ago, on the basis of their ability to kill tumor cells in vitro and to cause hemorrhagic necrosis of transplantable tumors in mice.1 The complementary DNAs and genes encoding each protein were cloned immediately thereafter.2,3 Concurrently, a factor known as cachectin was ...
BAZZONI, Flavia, BEUTLER B.
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Tumor necrosis factor receptors-structure and function
Immunologic Research, 1992Tumor necrosis factors (TNFs) have been a focus of research for well over a decade now. The identification and recent molecular cloning of two different types of cell-surface TNF receptors will shed further light on the mode of action of these pleiotropic cytokines.
J, Rothe +3 more
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Assay of Soluble Tumor Necrosis Factor Receptors
2003Over the last decade, numerous basic biological as well as experimental and clinical studies have firmly established the significance of tumor necrosis factor (TNF) as a principal proximal mediator of sepsis (1-4). One of the major insights that has emerged during recent years has been that under physiological circumstances, TNF activity is tightly ...
Boumaand, M.G., Buurman, W.A.
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