Results 151 to 160 of about 14,304 (250)

The mechanism of signal transduction by the GPI anchored Prod 1 protein

, 2010
Salamanders such as the red spotted newt Notophthalamus viridescens and the axolotl Ambystoma mexicanum regenerate a number of anatomical structures following injury.
Blassberg, R.A.
core  

The Aging Microenvironment Shapes Angiogenic Remodeling in IBD‐Associated Colorectal Carcinogenesis

Aging Cell, Volume 25, Issue 6, June 2026.
In IBD, chronic inflammation promotes cellular senescence across epithelial, stromal, endothelial, and immune compartments. The resulting SASP drives pathological angiogenesis, vascular dysfunction, hypoxia, and immune suppression, thereby facilitating progression from inflammation to dysplasia and colitis‐associated colorectal cancer.
Ruoshu Duan, Qingyu Chen, Yuan Xu, Ye Yan, Sujing Jiang   +4 more
wiley   +1 more source

IL‐17RA/RC blockade modulates the fibrinolytic system and MMP activity in bleomycin‐induced pulmonary fibrosis in male mice

Physiological Reports, Volume 14, Issue 12, June 2026.
Abstract Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with excessive accumulation of extracellular matrix (ECM) components, which leads to disrupted lung architecture and respiratory failure. Interleukin (IL)‐17 signaling induces fibrosis through inflammation; however, specific roles of its receptors IL‐1RA and IL‐17RC in ...
Rakshitha Charavu, Jeena Thrikkandiyoor Madambath, Akarsha B. Jain, Yashodhar P. Bhandary   +3 more
wiley   +1 more source

Urokinase-type plasminogen-activator and normal thyroid cell adhesion to the extracellular matrix

, 1999
The urokinase-type plasminogen activator receptor (uPA-R) focuses the proteolytic activity of its ligand, the urokinase-type plasminogen activator (uPA), on the cell surface, and can also act as an adhesion receptor for vitronectin (VTN).
RAGNO, Pia, G. ROSSI, S. SALZANO, ROSSI, GUIDO, SALZANO S, N. MONTUORI, MONTUORI, NUNZIA   +6 more
core  

Plasminogen Activator Inhibitor‐1 is Internalized by Endothelial Cells via A Pinocytosis‐Like Mechanism and Evades Degradation

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Plasminogen activator inhibitor 1 (PAI1) is a secreted protein that also regulates intracellular processes, such as inhibition of endothelial nitric oxide synthase (eNOS). Interaction between Plasminogen Activators (PA) and PAI1 results in a covalent linkage.
Molly McAdow, Gjina Ahmetaj, Rachel Hauschel, Anne Eichmann, William Sessa   +4 more
wiley   +1 more source

Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors [PDF]

The Journal of cell biology, 1987
Blasi, F., Vassalli, Jean-Dominique, Dano, K.   +2 more
openaire   +3 more sources

Soluble urokinase plasminogen activator receptor in sepsis and critical illness

, 2015
Diese Arbeit beschäftigt sich mit der Diagnose und Prognose von Sepsis und schwerer Erkrankung mittels löslicher Form des urokinase-type Plasminogen Activator Receptors, kurz suPAR genannt.
Groschopf, Alina
core  

Urokinase-dependent plasminogen binding and activation on breast cancer cells: an important process linked to malignancy

, 2008
Cellular invasion is facilitated by localisation and activation of the human circulating zymogen plasminogen. Increased binding and activation of plasminogen at the surface of invasive breast cancer cells has been linked to the inappropriate and ...
Gillian Stillfried (20123934)
core  

Expression of urokinase receptors by human trophoblast. A histochemical and ultrastructural analysis.

, 1994
Udgivelsesdato: 1994-SepBACKGROUND: Through their ability to invade endometrium, remodel the uterine spiral arteries, and sustain placental blood fluidity, trophoblast cells play a central role in establishing and maintaining the integrity of the ...
McCrae, K R, Cines, D B, Mazar, A, Multhaupt, H A, Warhol, M J   +4 more
core  

Targeting of peptide conjugated magnetic nanoparticles to urokinase plasminogen activator receptor (uPAR) expressing cells

, 2013
Ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles are currently being used as a magnetic resonance imaging (MRI) contrast agent in vivo, mainly by their passive accumulation in tissues of interest. However, a higher specificity can ideally be
Kjems, Jørgen, Pedersen, Michael, Hansen, Line, Thomsen, Karen Sand, Nielsen, Erik Holm, Iversen, Frank Horsbøl, Ploug, Michael, Larsen, Esben Kjær Unmack, Nielsen, Niels Chr, Liu, Zhuo, Skrydstrup, Troels   +10 more
core   +1 more source