Results 271 to 280 of about 10,420,356 (335)

Signaling via vascular endothelial growth factor receptors.

Experimental Cell Research, 1999
Angiogenesis, or development of blood vessels from preexisting vasculature, has important functions under both normal and pathophysiological conditions. Vascular endothelial growth factor receptors 1-3, also known as flt-1, KDR, and flt-4, are endothelial cell-specific receptor tyrosine kinases which serve as key mediators of the angiogenic responses ...
T. Petrova, T. Makinen, K. Alitalo
semanticscholar   +4 more sources

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Vascular endothelial growth factor and its receptors.

Cytokine & Growth Factor Reviews, 1996
Vascular endothelial growth factor (VEGF) is a prime regulator of endothelial cell proliferation, angiogenesis, vasculogenesis and vascular permeability. Its activity is mediated by the high affinity tyrosine kinase receptors, KDR/Fik-1 and Fit-1. In this article, recently discovered structural, molecular and biological properties of VEGF are described.
M. Klagsbrun, P. D'Amore
semanticscholar   +3 more sources

Vascular endothelial growth factor (VEGF) and its receptors

The FASEB Journal, 1999
ABSTRACT Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a single VEGF gene. These isoforms differ in their molecular mass and in biological properties such as their ability to bind to ...
G. Neufeld, T. Cohen, S. Gengrinovitch, Zoya Poltorak   +3 more
semanticscholar   +3 more sources

The role of estrogen receptors, erbB receptors, vascular endothelial growth factor and its receptors, and vascular endothelial growth inhibitor in the development of the rat mammary gland

Growth Factors, 2010
We identified the localization and distribution of cell-specific epidermal growth factor receptors (EGFRs erbB-1, erbB-2, erbB-3, erbB-4), vascular endothelial growth factor (VEGF), VEGF receptors [VEGFRs VEGF-R1 (fit-1), VEGF-R2 (flk-1/KDR), VEGF-R3 ...
H. Sagsoz, M. Ketani
semanticscholar   +2 more sources

Vascular Endothelial Growth Factor and its Receptors

Retina, 1994
Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells and an angiogenic factor that is structurally related to platelet derived growth factor (PDGF). It is also known as the vascular permeability factor (VPF) because it efficiently potentiates the permeabilization of blood vessels. Five types of VEGF mRNA
G, Neufeld, S, Tessler, H, Gitay-Goren, T, Cohen, B Z, Levi   +4 more
openaire   +2 more sources

Multimodality imaging of vascular endothelial growth factor and vascular endothelial growth factor receptor expression

Frontiers in Bioscience, 2007
Angiogenesis is a critical process in both physiological development and many pathological processes. Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling pathway plays a pivotal role in regulating angiogenesis. Many therapeutic agents targeting VEGF and VEGFR are currently in preclinical and clinical development.
Weibo, Cai, Xiaoyuan, Chen
openaire   +2 more sources

Role of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptors in Vascular Development

1999
Distinct cellular processes mediate blood-vessel formation during embryogenesis (Beck and D’Amore 1997; Carmeliet and Collen 1998a; Folkman and D’Amore 1996; Noden 1989; Risau 1997; Wilting and Christ 1996) (Fig. 1). Initially, mesodermal cells differentiate in situ into early haemangioblasts and form cellular aggregates (blood islands), in which the ...
P, Carmeliet, D, Collen
openaire   +2 more sources

Ovarian vascular endothelial growth factor and vascular endothelial growth factor receptor patterns in reproductive aging

Fertility and Sterility, 2008
To investigate how levels of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) change during corpus luteum formation in reproductive aging.Adult and reproductive aging female rats were given pregnant mare serum gonadotropin (PMSG) and the ovaries and sera were collected at 0, 3, 5, and 7 days after human chorionic gonadotropin (hCG ...
John, Yeh, Beom Su, Kim, Jennifer, Peresie   +2 more
openaire   +2 more sources