Results 41 to 50 of about 491,094 (347)

Characterization of Novel Vascular Endothelial Growth Factor (VEGF) Receptors on Tumor Cells That Bind VEGF via Its Exon 7-encoded Domain (*)

Journal of Biological Chemistry, 1996
Vascular endothelial growth factor (VEGF), a potent angiogenic factor, uses two receptor tyrosine kinases, FLK/KDR and FLT, to mediate its activities. We have cross-linked I-VEGF to the cell surface of various tumor cell lines and of human umbilical vein
S. Soker, H. Fidder, G. Neufeld, M. Klagsbrun   +3 more
semanticscholar   +1 more source

Vascular Endothelial Growth Factor Ligands and Receptors in Breast Cancer

Journal of Clinical Medicine, 2023
Breast cancer (BC) is the most common malignancy responsible for the largest number of deaths in women worldwide. The risk of developing BC is predisposed by many factors such as age, presence of genetic mutations or body weight. The diagnosis is mostly made relatively late, which is why patients are exposed to radical surgical treatments, long-term ...
Klaudia Katarzyna Brogowska, Monika Zajkowska, Barbara Mroczko   +2 more
openaire   +2 more sources

Activity of cabozantinib in radioresistant brain metastases from renal cell carcinoma: two case reports

Journal of Medical Case Reports, 2018
Background Renal cell carcinoma represents 3–5% of adult malignant tumors. Metastases are found in 30–40% of patients and brain metastases occurred in more than 10% of them.
Sylvie Négrier, Guillaume Moriceau, Valéry Attignon, Véronique Haddad, Daniel Pissaloux, Nicole Guerin, Christian Carrie   +6 more
doaj   +1 more source

Abl family kinases regulate endothelial barrier function in vitro and in mice. [PDF]

PLoS ONE, 2013
The maintenance of endothelial barrier function is essential for normal physiology, and increased vascular permeability is a feature of a wide variety of pathological conditions, leading to complications including edema and tissue damage.
Elizabeth M Chislock, Ann Marie Pendergast   +1 more
doaj   +1 more source

Anti-angiogenic and antioxidant effects of axitinib in human retinal endothelial cells: implications in diabetic retinopathy

Frontiers in Pharmacology
Diabetic retinopathy is a secondary microvascular complication of diabetes mellitus. This disease progresses from two stages, non-proliferative and proliferative diabetic retinopathy, the latter characterized by retinal abnormal angiogenesis ...
Francesca Lazzara, Federica Conti, Pradip K. Sasmal, Shanavas Alikunju, Settimio Rossi, Filippo Drago, Filippo Drago, Chiara Bianca Maria Platania, Chiara Bianca Maria Platania, Claudio Bucolo, Claudio Bucolo   +10 more
doaj   +1 more source

Factors of angiogenesis in the development of physiological and pathological processes of the female gonads

Бюллетень сибирской медицины, 2016
The literature review focuses on the role of various growth factors in the developing vasculature of the ovary. Vascularization plays an important role in physiological processes such as development and atresia of a follicle, the formation of the yellow ...
V. G. Zenkina
doaj   +1 more source

A multiscale hybrid model for pro-angiogenic calcium signals in a vascular endothelial cell [PDF]

, 2012
Cytosolic calcium machinery is one of the principal signaling mechanisms by which endothelial cells (ECs) respond to external stimuli during several biological processes, including vascular progression in both physiological and pathological conditions ...
A. Balter, A. F. M. Marée, A. F. M. Marée, A. Fiorio Pla, A. Fiorio Pla, A. Fiorio Pla, A. Hunding, A. L. Bauer, A. M. Patton, A. Mottola, A. Tosin, A. W. Mahoney, B. Alberts, B. Nilius, C. C. Fink, C. D. Nobes, C. J. Drake, C. R. Kahl, C. Tomatis, D. Ambrosi, D. E. Clapham, D. Hong, D. Lovisolo, D. Wang, E. C. Kohn, E. C. Kohn, E. D. Perryn, E. L. Watson, F. Bussolino, F. Graner, F. Mac Gabhann, F. Moccia, G. Barbiero, G. Serini, H. Gerhardt, H. Kimura, H.-Y. Kwan, I. Fleming, J. A. Glazier, J. A. Glazier, J. Bennett, J. Howard, J. Klingauf, J. M. Haugh, J. R. Lancaster Jr., J. S. Pollock, J. Sneyd, J. Sneyd, K. S. Bauer, L. A. Blatter, L. Munaron, L. Munaron, L. Munaron, L. Munaron, L. Munaron, L. Munaron, L. Munaron, L. Munaron, L. Santella, L. V. Hryshko, M. A. Albrecht, M. D. Bootman, M. J. Berridge, M. J. Berridge, M. J. Berridge, M. J. Berridge, M. Kraus, M. S. Jafri, M. S. Steinberg, M. S. Steinberg, M. Scianna, M. Scianna, Marco Scianna, N. J. Poplawski, N. J. Savill, N. Metropolis, N. Wang, P. A. Valant, P. Bayley, P. Carmeliet, P. Carmeliet, P. Pacher, R. E. Dolmetsch, R. M. H. Merks, R. M. H. Merks, R. M. H. Merks, R. M. H. Merks, R. Meili, R. Rizzuto, S. Etienne-Manneville, S. Feske, S. Funamoto, S. Huang, S. Lin, S. M. Rafelski, S. Mittara, S. P. Khanapure, S. Wang, T. D. Pollard, T. Walther, W. Coatesworth, Y. Goto, Y. Takai   +102 more
core   +1 more source

Vascular endothelial growth factor signaling in development and disease

Development, 2018
Vascular endothelial growth factors (VEGFs) are best known for their involvement in orchestrating the development and maintenance of the blood and lymphatic vascular systems.
Sinem Karaman, V. Leppänen, K. Alitalo
semanticscholar   +1 more source

Microvascularization and Expression of Fibroblast Growth Factor and Vascular Endothelial Growth Factor and Their Receptors in the Mare Oviduct

Animals, 2021
The oviduct presents the ideal conditions for fertilization and early embryonic development. In this study, (i) vascularization pattern; (ii) microvascular density; (iii) transcripts of angiogenic factors (FGF1, FGF2, VEGF) and their receptors—FGFR1 ...
Pedro Pinto-Bravo, Maria Rosa Rebordão, Ana Amaral, Carina Fernandes, António Galvão, Elisabete Silva, Pedro Pessa-Santos, Graça Alexandre-Pires, Rosário P. Roberto da Costa, Dariusz J. Skarzynski, Graça Ferreira-Dias   +10 more
doaj   +1 more source

Nuclear receptors in vascular biology [PDF]

, 2015
Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics.
A Chawla, A McCurley, AA Hamers, AL Bookout, B Fisslthaler, BG Hoebel, C McCarthy, C Zhou, CH Lee, CK Glass, CK Huang, CT Lee, D Bishop-Bailey, D Bishop-Bailey, David Bishop-Bailey, DP Edwards, E Gerlach, F Akbiyik, FA Pereira, FL Wynne, FY Ali, G Pascual, I Dussault, I Spoletini, J He, J Qin, J Sonoda, J Xiang, K Spruiell, KE Swales, L Calza, L Li, L Piqueras, LA Moraes, LA Moraes, LJ Jonk, LR You, M Kaushik, M Matic, N Albermann, N Schafer, N Takamoto, Q Qin, R Zhao, S Asgary, S Chakrabarti, S Marino De, S Stein, SA Kliewer, V Zoete, W El-Sankary, WC Lau, X Wang, Y Ma, Y Sui, Y Sui, YW Hu   +56 more
core   +3 more sources