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Vasoactive Intestinal Peptide in Thymus: Synthesis, Receptors and Biological Actions
Neuroimmunomodulation, 1999Evidence summarized in this report indicates that thymocytes produce and secrete VIP. Moreover, different stimuli such as Con A, LPS and anti-TCR antibody induce a significant increase in VIP production by thymocytes. In addition, proinflammatory cytokines such as IL-1, IL-6 and TNF-α, but not IL-2, stimulate in a similar time-dependent manner VIP ...
M, Delgado +3 more
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The vasoactive intestinal peptide (VIP) receptor: recent data and hypothesis
Biochimie, 1988Vasoactive intestinal peptide (VIP) is a neuropeptide with a broad range of biological activities in various tissues. After interaction with its membrane receptor, VIP generally induces a very large increase in the intracellular cyclic AMP level. Receptors for VIP have been described in numerous tissues and cell lines. The first results on VIP receptor
J, Luis +4 more
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Ontogeny of vasoactive intestinal peptide receptors in rat ventral prostate
General Pharmacology: The Vascular System, 19941. The stimulatory effect of VIP on rat prostatic adenylyl cyclase changes during postnatal development. It peaks at 2 months (peripubertal period), remains in a plateau between 3 and 12 months (adult period), and decreases at 24 months (old period). 2.
M G, Juarranz +4 more
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Vasoactive intestinal peptide receptor localization in rat forebrain by autoradiography
Neuroscience Letters, 1985Vasoactive intestinal peptide (VIP) receptors were localized in rat forebrain by in vitro labeling light microscopic autoradiography with 125I-labeled VIP. Binding sites for VIP were found in discrete areas of rat forebrain including lamina I of the neocortex and pyriform cortex, caudate-putamen, the hippocampus and molecular layer of the dentate gyrus,
E B, De Souza, H, Seifert, M J, Kuhar
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The Journal of Pharmacology and Experimental Therapeutics, 2005
Vasoactive intestinal peptide (VIP) is a widespread neurotransmitter whose physiological and pathophysiological actions are mediated by two receptor classes, VIP/pituitary adenylate cyclase-activating polypeptide (VPAC) 1 and VPAC2. VIP is a 28-amino acid peptide that is rapidly degraded and simplified; metabolically stable analogs are needed.
Hisato, Igarashi +6 more
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Vasoactive intestinal peptide (VIP) is a widespread neurotransmitter whose physiological and pathophysiological actions are mediated by two receptor classes, VIP/pituitary adenylate cyclase-activating polypeptide (VPAC) 1 and VPAC2. VIP is a 28-amino acid peptide that is rapidly degraded and simplified; metabolically stable analogs are needed.
Hisato, Igarashi +6 more
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Ontogenic Development of Vasoactive Intestinal Peptide Receptors in Rat Intestinal Cells and Liver*
Endocrinology, 1987Changes in the functional and biochemical characteristics of membrane receptors for vasoactive intestinal peptide (VIP) were evaluated in vitro, using epithelial intestinal cells isolated during rat development, from day 17 of gestation to adulthood.
E, Chastre +3 more
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Regulation of the Vasoactive Intestinal Peptide Receptor
Annals of the New York Academy of Sciences, 1988G, Rosselin +6 more
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The Airway and Vasoactive Intestinal Peptide Autoantibodies and Receptors
2020This chapter outlines observations on human autoantibodies directed against vasoactive intestinal peptide (VIP), the functional properties of these autoantibodies, and their relevance to disease; and characteristics, regulatory features, and signal-transducing pathways utilized by the VIP receptor in guinea pig lung.
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
99mTc-labeled vasoactive intestinal peptide receptor agonist: functional studies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999Vasoactive intestinal peptide (VIP) is a naturally occurring 28-amino acid peptide with a wide range of biological activities. Recent reports suggest that VIP receptors are expressed on a variety of malignant tumor cells and that the receptor density is higher than for somatostatin.
V R, Pallela +3 more
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