Results 11 to 20 of about 14,521 (208)

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system [version 1; peer review: 4 approved]

open access: yesF1000Research, 2019
Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a vasodilator in 1970, has multiple physiological and pathological effects on development, growth, and the control of neuronal, epithelial, and endocrine cell functions ...
Mari Iwasaki   +2 more
doaj   +1 more source

G Protein-Coupled Receptors as Potential Intercellular Communication Mediators in Trypanosomatidae

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Detection and transduction of environmental signals, constitute a prerequisite for successful parasite invasion; i.e., Leishmania transmission, survival, pathogenesis and disease manifestation and dissemination, with diverse molecules functioning as ...
Emilia Díaz   +7 more
doaj   +1 more source

Glycyrrhizic Acid Reduces Heart Rate and Blood Pressure by a Dual Mechanism

open access: yesMolecules, 2016
Beta adrenergic receptors are crucial for their role in rhythmic contraction of heart along with their role in the pathological conditions such as tachycardia and high risk of heart failure.
Kailash Singh   +6 more
doaj   +1 more source

Characterization of vasoactive intestinal peptide receptors in retina

open access: yesExperimental Eye Research, 1990
Vasoactive intestinal peptide (VIP) is a neuropeptide having a wide range of effects on a large number of tissues. To gain insight into the role VIP plays in retinal function, VIP receptors in bovine retinal membranes were analyzed in competition binding assays and by affinity labeling studies and compared to VIP receptors in rat liver membranes.
A P, Swedlund, S A, Rosenzweig
openaire   +2 more sources

Neuroimmune communication in allergic rhinitis

open access: yesFrontiers in Neurology, 2023
The prevalence rate of allergic rhinitis (AR) is high worldwide. The inhalation of allergens induces AR, which is an immunoglobulin E-mediated and type 2 inflammation-driven disease.
Yi Zhou   +7 more
doaj   +1 more source

Neuropeptide G Protein-Coupled Receptors as Oncotargets

open access: yesFrontiers in Endocrinology, 2018
Neuropeptide G protein-coupled receptors (GPCRs) are overexpressed on numerous cancer cells. In a number of tumors, such as small cell lung cancer (SCLC), bombesin (BB) like peptides and neurotensin (NTS) function as autocrine growth factors whereby they
Terry W. Moody   +2 more
doaj   +1 more source

Neuropeptide Receptors: Novel Targets for HIV/AIDS Therapeutics

open access: yesPharmaceuticals, 2011
The vasoactive intestinal peptide/pituitary adenylyl cyclase-activating polypepetide (VPAC) receptors are important for many physiologic functions, including glucose homeostasis, neuroprotection, memory, gut function, modulation of the immune system and ...
Donald R. Branch
doaj   +1 more source

Tracing the Origins of the Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP)

open access: yesFrontiers in Neuroscience, 2020
Pituitary adenylate cyclase activating polypeptide (PACAP) is a well-conserved neuropeptide characteristic of vertebrates. This pluripotent hypothalamic neuropeptide regulates neurotransmitter release, intestinal motility, metabolism, cell division ...
João C. R. Cardoso   +2 more
doaj   +1 more source

Detection of bladder cancer using voided urine sample and by targeting genomic VPAC receptors

open access: yesIndian Journal of Urology, 2021
Introduction: Cells exfoliated into urine from the bladder can help to diagnose the cancer. The objective of this study was to validate the hypothesis that bladder cancer could be detected noninvasively by a simple and reliable assay targeting genomic ...
Rajendra B Nerli   +5 more
doaj   +1 more source

Vasoactive intestinal peptide receptors in rat liver after partial hepatectomy [PDF]

open access: yesBiochemical Journal, 1992
We describe the status of vasoactive intestinal peptide (VIP) receptors in regenerating liver. VIP-stimulated adenylate cyclase activity was markedly decreased in proliferating liver 3 days after partial (70%) hepatectomy. This was associated with a reduced efficacy of VIP (53% compared with controls), with no change in the potency of the peptide (ED50
L G, Guijarro   +7 more
openaire   +2 more sources

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