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EVIHVR: A platform for analysis of expression, variation and identification of human virus receptors

open access: yesInfectious Medicine, 2022
Motivation: Virus receptors are presented on the cell surfaces of a host and are key for viral infection of host cells. However, no unified resource for the study of viral receptors is currently available.
Zheng Zhang   +4 more
doaj   +1 more source

Interactions between the rabies virus and nicotinic acetylcholine receptors: A potential role in rabies virus induced behavior modifications

open access: yesHeliyon, 2022
Rabies causes approximately 60,000 casualties annually and has a case fatality rate approaching 100% once clinical signs occur. The glycoprotein on the surface of the virion is important for the host immune response and facilitates interaction of the ...
Marianne Lian   +2 more
doaj   +1 more source

Interaction Analysis of Adenovirus L5 Protein With Pancreatic Cancer Cell Surface Receptor to Analyze Its Affinity for Oncolytic Virus Therapy

open access: yesFrontiers in Oncology, 2022
This study seeks to investigate the interaction profile of the L5 protein of oncolytic adenovirus with the overexpressed surface receptors of pancreatic cancer.
Maryum Nisar   +8 more
doaj   +1 more source

Influenza A Virus Hemagglutinin and Other Pathogen Glycoprotein Interactions with NK Cell Natural Cytotoxicity Receptors NKp46, NKp44, and NKp30

open access: yesViruses, 2021
Natural killer (NK) cells are part of the innate immunity repertoire, and function in the recognition and destruction of tumorigenic and pathogen-infected cells.
Jasmina M. Luczo   +2 more
doaj   +1 more source

A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]

open access: yes, 2012
© 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
AM Kilpatrick   +49 more
core   +11 more sources

Influenza–Host Interplay and Strategies for Universal Vaccine Development

open access: yesVaccines, 2020
Influenza is an annual epidemic and an occasional pandemic caused by pathogens that are responsible for infectious respiratory disease. Humans are highly susceptible to the infection mediated by influenza A viruses (IAV).
Hye Suk Hwang   +2 more
doaj   +1 more source

PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection [PDF]

open access: yes, 2010
Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these virus particles to CD4+ T cells ...
Blay Puryear, Wendy   +3 more
core   +11 more sources

Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta

open access: yesViruses, 2022
Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta.
Yan-Na Xiao   +3 more
doaj   +1 more source

Influenza Virus Infections in Polarized Cells

open access: yesViruses, 2022
In humans and other mammals, the respiratory tract is represented by a complex network of polarized epithelial cells, forming an apical surface facing the external environment and a basal surface attached to the basement layer.
Beatriz Praena, Xiu-Feng Wan
doaj   +1 more source

Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. [PDF]

open access: yes, 2017
Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F ...
Jardetzky, Theodore S   +9 more
core   +2 more sources

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