Results 1 to 10 of about 50 (49)
Folia Microbiologica, 1999 The term 'receptor' is generally accepted as the cell-surface component that participates in virus binding and facilitates subsequent viral infection. Recent advances in technology have permitted the identification of several virus receptors, increasing our understanding of the significance of this initial virus-cell and virus-host interaction.
Libor Grubhoffer +3 more
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Identification of a receptor for an extinct virus [PDF]
Proceedings of the National Academy of Sciences, 2010 The resurrection of endogenous retroviruses from inactive molecular fossils has allowed the investigation of interactions between extinct pathogens and their hosts that occurred millions of years ago. Two such paleoviruses, chimpanzee endogenous retrovirus-1 and -2 (CERV1 and CERV2), are relatives of modern MLVs and are found in the ...
Soll, Steven J. +2 more
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Journal of NeuroVirology, 2005 There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind rabies virus and/or facilitate rabies virus entry into cells.
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Tropical Medicine and Health, 2011 Dengue virus is an arthropod-borne virus transmitted by Aedes mosquitoes. Dengue virus causes fever and hemorrhagic disorders in humans and non-human primates. Direct interaction of the virus introduced by a mosquito bite with host receptor molecule(s) is crucial for virus propagation and the pathological progression of dengue diseases.
Takashi Suzuki, Kazuya I.P.J. Hidari
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Oligosaccharides as Receptors for JC Virus [PDF]
Journal of Virology, 2002 ABSTRACT JC virus (JCV) belongs to the polyomavirus family of double-stranded DNA viruses and in humans causes a demyelinating disease of the central nervous system, progressive multifocal leukoencephalopathy. Its hemagglutination activity and entry into host cells have been reported to depend on an N-linked glycoprotein containing sialic ...
Shinya Tanaka +6 more
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Virus sensing receptors in cellular infectivity of influenza A virus
The Journal of Infection in Developing Countries, 2021 An innate immune response is essential to mobilize protective immunity upon the infection of respiratory epithelial cells with influenza A virus (IAV). The response is classified as early (nonspecific effectors), local systematic (effector cells recruitment) and late (antigen to lymphoid organ transport, naive B and T cells recognition, effector cells ...
Shaihana Almatrrouk +4 more
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Virus recognition of glycan receptors
Current Opinion in Virology, 2019 Attachment of viruses to cell-surface receptors is the initial step in infection. Many mammalian viruses have evolved to recognize receptors that are glycans on cell-surface glycoproteins or glycolipids. Although glycans are a ubiquitous component of mammalian cells, the types of terminal structures expressed vary among different cell-types and tissues,
Andrew J Thompson +2 more
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Receptors for Hepatitis C Virus
Journal of Virology, 2000 The nature of the receptors enabling hepatitis C virus (HCV) entry into cells has been the subject of debate. On one hand, ligand panning with recombinant HCV envelope protein has identified CD81, a member of the tetraspanin superfamily of proteins, as a direct ligand for the E2 glycoprotein (7) but fails to explain virus tropism.
Ian M. Jones +3 more
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Specificity switching in virus–receptor complexes [PDF]
Current Opinion in Structural Biology, 2009 Several structures of complexes between viral attachment proteins and their cellular receptors have been determined recently, enhancing our understanding of the molecular recognition processes that guide formation of virus-receptor complexes. Moreover, these structures also highlight strategies by which highly similar viral proteins within a single ...
Thilo Stehle +2 more
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Virus-Receptor Interactions and Receptor-Mediated Virus Entry into Host Cells [PDF]
, 2013 The virus particles described in the previous chapters of this book are vehicles that transmit the viral genome and the infection from cell to cell. To initiate the infective cycle, the viral genome must therefore translocate from the viral particle to the cell cytoplasm. Via distinct proteins or motifs in their outermost shell, the particles of animal
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