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Pattern recognition receptors and their roles in antiviral innate immunity in livestock [PDF]
Frontiers in ImmunologyViral infectious diseases pose a persistent challenge to global livestock production, animal welfare, and food security, emphasizing the critical role of early host defense mechanisms in limiting viral replication and transmission.
Shujing Liu +8 more
doaj +2 more sources
EVIHVR: A platform for analysis of expression, variation and identification of human virus receptors
Infectious Medicine, 2022 Motivation: Virus receptors are presented on the cell surfaces of a host and are key for viral infection of host cells. However, no unified resource for the study of viral receptors is currently available.
Zheng Zhang +4 more
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Heliyon, 2022 Rabies causes approximately 60,000 casualties annually and has a case fatality rate approaching 100% once clinical signs occur. The glycoprotein on the surface of the virion is important for the host immune response and facilitates interaction of the ...
Marianne Lian +2 more
doaj +1 more source
Frontiers in Oncology, 2022 This study seeks to investigate the interaction profile of the L5 protein of oncolytic adenovirus with the overexpressed surface receptors of pancreatic cancer.
Maryum Nisar +8 more
doaj +1 more source
Viruses, 2021 Natural killer (NK) cells are part of the innate immunity repertoire, and function in the recognition and destruction of tumorigenic and pathogen-infected cells.
Jasmina M. Luczo +2 more
doaj +1 more source
Influenza–Host Interplay and Strategies for Universal Vaccine Development
Vaccines, 2020 Influenza is an annual epidemic and an occasional pandemic caused by pathogens that are responsible for infectious respiratory disease. Humans are highly susceptible to the infection mediated by influenza A viruses (IAV).
Hye Suk Hwang +2 more
doaj +1 more source
Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta
Viruses, 2022 Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta.
Yan-Na Xiao +3 more
doaj +1 more source
Influenza Virus Infections in Polarized Cells
Viruses, 2022 In humans and other mammals, the respiratory tract is represented by a complex network of polarized epithelial cells, forming an apical surface facing the external environment and a basal surface attached to the basement layer.
Beatriz Praena, Xiu-Feng Wan
doaj +1 more source
Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. [PDF]
, 2017 Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F ...
Jardetzky, Theodore S +9 more
core +2 more sources
Measles virus glycoprotein-based lentiviral targeting vectors that avoid neutralizing antibodies [PDF]
, 2012 Lentiviral vectors (LVs) are potent gene transfer vehicles frequently applied in research and recently also in clinical trials. Retargeting LV entry to cell types of interest is a key issue to improve gene transfer safety and efficacy.
Abel, Tobias +5 more
core +10 more sources