Results 1 to 10 of about 365,174 (219)

EVIHVR: A platform for analysis of expression, variation and identification of human virus receptors

Infectious Medicine, 2022
Motivation: Virus receptors are presented on the cell surfaces of a host and are key for viral infection of host cells. However, no unified resource for the study of viral receptors is currently available.
Zheng Zhang, Zena Cai, Longfei Mao, Xing-Yi Ge, Yousong Peng   +4 more
doaj   +1 more source

Interactions between the rabies virus and nicotinic acetylcholine receptors: A potential role in rabies virus induced behavior modifications

Heliyon, 2022
Rabies causes approximately 60,000 casualties annually and has a case fatality rate approaching 100% once clinical signs occur. The glycoprotein on the surface of the virion is important for the host immune response and facilitates interaction of the ...
Marianne Lian, Karsten Hueffer, Maegan M. Weltzin   +2 more
doaj   +1 more source

Interaction Analysis of Adenovirus L5 Protein With Pancreatic Cancer Cell Surface Receptor to Analyze Its Affinity for Oncolytic Virus Therapy

Frontiers in Oncology, 2022
This study seeks to investigate the interaction profile of the L5 protein of oncolytic adenovirus with the overexpressed surface receptors of pancreatic cancer.
Maryum Nisar, Rehan Zafar Paracha, Alvina Gul, Iqra Arshad, Saima Ejaz, Didar Murad, Shahzeb Khan, Shahzeb Khan, Zartasha Mustansar   +8 more
doaj   +1 more source

Influenza A Virus Hemagglutinin and Other Pathogen Glycoprotein Interactions with NK Cell Natural Cytotoxicity Receptors NKp46, NKp44, and NKp30

Viruses, 2021
Natural killer (NK) cells are part of the innate immunity repertoire, and function in the recognition and destruction of tumorigenic and pathogen-infected cells.
Jasmina M. Luczo, Sydney L. Ronzulli, Stephen M. Tompkins   +2 more
doaj   +1 more source

Influenza–Host Interplay and Strategies for Universal Vaccine Development

Vaccines, 2020
Influenza is an annual epidemic and an occasional pandemic caused by pathogens that are responsible for infectious respiratory disease. Humans are highly susceptible to the infection mediated by influenza A viruses (IAV).
Hye Suk Hwang, Mincheol Chang, Yoong Ahm Kim   +2 more
doaj   +1 more source

Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta

Viruses, 2022
Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta.
Yan-Na Xiao, Fei-Yuan Yu, Qian Xu, Jiang Gu   +3 more
doaj   +1 more source

Influenza Virus Infections in Polarized Cells

Viruses, 2022
In humans and other mammals, the respiratory tract is represented by a complex network of polarized epithelial cells, forming an apical surface facing the external environment and a basal surface attached to the basement layer.
Beatriz Praena, Xiu-Feng Wan
doaj   +1 more source

Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application

Haematologica, 2008
Background Donor lymphocyte infusion is an effective form of adoptive immunotherapy for hematologic malignancies after allogeneic stem cell transplantation.
Marieke Griffioen, H.M. Esther van Egmond, Helen Barnby-Porritt, Menno A.W.G. van der Hoorn, Renate S. Hagedoorn, Michel G.D. Kester, Nikolai Schwabe, Roel Willemze, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk   +9 more
doaj   +1 more source

Host Cellular Receptors for the Peste des Petits Ruminant Virus

Viruses, 2019
Peste des Petits Ruminant (PPR) is an important transboundary, OIE-listed contagious viral disease of primarily sheep and goats caused by the PPR virus (PPRV), which belongs to the genus Morbillivirus of the family Paramyxoviridae.
Meera Prajapati, Niyokwishimira Alfred, Yongxi Dou, Xiangping Yin, Raju Prajapati, Yanmin Li, Zhidong Zhang   +6 more
doaj   +1 more source

Phosphatidylserine treatment relieves the block to retrovirus infection of cells expressing glycosylated virus receptors

Retrovirology, 2005
Background A major determinant of retrovirus host range is the presence or absence of appropriate cell-surface receptors required for virus entry. Often orthologs of functional receptors are present in a wide range of species, but amino acid differences ...
Coil David A, Miller A Dusty
doaj   +1 more source