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Highly pathogenic avian H5N1 influenza A virus replication in ex vivo cultures of bovine mammary gland and teat tissues [PDF]
Emerging Microbes and InfectionsSince early 2024, highly pathogenic avian influenza H5N1 viruses have been causing outbreaks in dairy cattle in the United States. Here, we compared the replicative capacity of A/dairy cattle/Texas/24-008749-001/2024 (H5N1; Cow-H5N1) isolated from a ...
Masaki Imai +11 more
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Insights into mosquito-borne arbovirus receptors [PDF]
Cell InsightThe increasing global prevalence of mosquito-borne viruses has emerged as a significant threat to human health and life. Identifying receptors for these viruses is crucial for improving our knowledge of viral pathogenesis and developing effective ...
Jianying Liu +6 more
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Frontiers in Oncology, 2022 This study seeks to investigate the interaction profile of the L5 protein of oncolytic adenovirus with the overexpressed surface receptors of pancreatic cancer.
Maryum Nisar +8 more
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Viruses, 2021 Natural killer (NK) cells are part of the innate immunity repertoire, and function in the recognition and destruction of tumorigenic and pathogen-infected cells.
Jasmina M. Luczo +2 more
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Folia Microbiologica, 1999 The term 'receptor' is generally accepted as the cell-surface component that participates in virus binding and facilitates subsequent viral infection. Recent advances in technology have permitted the identification of several virus receptors, increasing our understanding of the significance of this initial virus-cell and virus-host interaction.
Libor Grubhoffer +3 more
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Influenza–Host Interplay and Strategies for Universal Vaccine Development
Vaccines, 2020 Influenza is an annual epidemic and an occasional pandemic caused by pathogens that are responsible for infectious respiratory disease. Humans are highly susceptible to the infection mediated by influenza A viruses (IAV).
Hye Suk Hwang +2 more
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A multitask transfer learning framework for the prediction of virus-human protein-protein interactions [PDF]
BMC Bioinformatics 2021, 2021 Viral infections are causing significant morbidity and mortality worldwide. Understanding the interaction patterns between a particular virus and human proteins plays a crucial role in unveiling the underlying mechanism of viral infection and pathogenesis. This could further help in the prevention and treatment of virus-related diseases.
arxiv +1 more source
Numerical simulation of the viral entry into a cell driven by receptor diffusion [PDF]
, 2021 The present study focuses on the receptor driven endocytosis typical of viral entry into a cell. A locally increased density of receptors at the time of contact between the cell and the virus is necessary in this case. The virus is considered as a substrate with fixed receptors on its surface, whereas the receptors of the host cell are free to move ...
arxiv +1 more source
Direct visualization of superselective colloid-surface binding mediated by multivalent interactions [PDF]
, 2021 Reliably distinguishing between cells based on minute differences in receptor density is crucial for cell-cell or virus-cell recognition, the initiation of signal transduction and selective targeting in directed drug delivery. Such sharp differentiation between different surfaces based on their receptor density can only be achieved by multivalent ...
arxiv +1 more source
Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta
Viruses, 2022 Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta.
Yan-Na Xiao +3 more
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