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Receptors for Hepatitis C Virus
Journal of Virology, 2000 The nature of the receptors enabling hepatitis C virus (HCV) entry into cells has been the subject of debate. On one hand, ligand panning with recombinant HCV envelope protein has identified CD81, a member of the tetraspanin superfamily of proteins, as a direct ligand for the E2 glycoprotein (7) but fails to explain virus tropism.
Ian M. Jones +3 more
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Specificity switching in virus–receptor complexes [PDF]
Current Opinion in Structural Biology, 2009 Several structures of complexes between viral attachment proteins and their cellular receptors have been determined recently, enhancing our understanding of the molecular recognition processes that guide formation of virus-receptor complexes. Moreover, these structures also highlight strategies by which highly similar viral proteins within a single ...
Thilo Stehle +2 more
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TAM Receptors Are Not Required for Zika Virus Infection in Mice
Cell Reports, 2017 Summary: Tyro3, Axl, and Mertk (TAM) receptors are candidate entry receptors for infection with the Zika virus (ZIKV), an emerging flavivirus of global public health concern.
Andrew K. Hastings +12 more
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Tumour Virus Research, 2021 Herpesviruses are ubiquitous viruses, specifically the Epstein Barr virus (EBV). EBV and Kaposi's sarcoma-associated herpesvirus (KSHV) establish their latency for a long period in B-cells and their reactivation instigates dreadful diseases from cancer ...
Annu Rani +4 more
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Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors
Nature Communications, 2014 Mammals express the sialic acids N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) on cell surfaces, where they act as receptors for pathogens, including influenza A virus (IAV).
Preston S K Ng +14 more
semanticscholar +1 more source
Virus-Receptor Interactions and Receptor-Mediated Virus Entry into Host Cells [PDF]
, 2013 The virus particles described in the previous chapters of this book are vehicles that transmit the viral genome and the infection from cell to cell. To initiate the infective cycle, the viral genome must therefore translocate from the viral particle to the cell cytoplasm. Via distinct proteins or motifs in their outermost shell, the particles of animal
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Transferrinfection. A Highly Efficient Way to Express Gene Constructs in Eukaryotic Cells [PDF]
, 1992 No abstract ...
Atherton +35 more
core +1 more source
The Role of Host Cell Glycans on Virus Infectivity: The SARS‐CoV‐2 Case
Advanced Science, 2023 Glycans are ubiquitously expressed sugars, coating the cell and protein surfaces. They are found on many proteins as either short and branched chains or long chains sticking out from special membrane proteins, known as proteoglycans.
Silvia Acosta‐Gutiérrez +2 more
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The epidermal growth factor receptor is not a receptor for vaccinia virus [PDF]
Journal of Virology, 1994 It has been suggested that the epidermal growth factor receptor (EGFR) is a receptor for vaccinia virus. Other reports, although not specifically addressing this question, did not support such a role for the EGFR. We addressed this issue by using wild-type virus and a virus growth factor deletion mutant, as well as sets of cells that do not express ...
A W Hügin, C Hauser
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Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
, 2016 Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
core +1 more source