Results 111 to 120 of about 5,911,760 (307)

Emerging Roles of NPQ/Spexin in Physiology and Pathology

open access: yesFrontiers in Pharmacology, 2019
Spexin (SPX), also called neuropeptide Q (NPQ), is a novel endogenous neuropeptide. Spexin gene and protein are widely expressed in central nervous system and peripheral tissues in humans, rodents, goldfish, etc.
Shuang-Yu Lv   +5 more
doaj   +1 more source

Frizzled Proteins are bona fide G Protein-Coupled Receptors [PDF]

open access: yes, 2009
Receptors of the Frizzled family initiate Wnt ligand-dependent signaling controlling multiple steps in organism development and highly conserved in evolution. Misactivation of the Wnt/Frizzled signaling is cancerogenic.
Silke Buestorf, Vladimir L. Katanaev
core   +1 more source

Two Amino Acid Residues Contribute to a Cation-π Binding Interaction in the Binding Site of an Insect GABA Receptor [PDF]

open access: yes, 2011
Cys-loop receptor binding sites characteristically possess an "aromatic box," where several aromatic amino acid residues surround the bound ligand. A cation-π interaction between one of these residues and the natural agonist is common, although the ...
Ashby, Jamie A.   +3 more
core  

A novel and selective fluorescent ligand for the study of adenosine A2B receptors

open access: yesPharmacology Research & Perspectives
Fluorescent ligands have proved to be powerful tools in the study of G protein‐coupled receptors in living cells. Here we have characterized a new fluorescent ligand PSB603‐BY630 that has high selectivity for the human adenosine A2B receptor (A2BR).
Foteini Patera   +8 more
doaj   +1 more source

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