Results 91 to 100 of about 1,379,490 (255)
Reactivity of recombinant antibody ADRI-2F3 versus human monoclonal ADRI-2F3.
, 2015 The titration curve shows that the recombinant antibody is about 10 times more reactive than the original human monoclonal antibody.
Dieter Glebe (421759) +3 more
core +1 more source
Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats
Toxins, 2019 Botulinum neurotoxins (BoNT) are potential biothreat agents due to their high lethality, potency, and ease of distribution, thus the development of antitoxins is a high priority to the US government.
Yero Espinoza +9 more
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Co-expression of Factor VIII with anti-FVIII Camelid antibody ligands: Effect on expression levels of bio-therapeutic FVIII [PDF]
, 2015 Production of recombinant FVIII, the protein that is missing or dysfunctional in haemophilia A patients, is highly inefficient compared to other recombinant clotting factors such as FIX.
Tolley, Caroline
core
Construction of gene recombinant IgG1 κ anti-P plasmids and their expression in HEK293T Cells
Zhongguo shuxue zazhi[Objective] To construct gene recombinant expression plasmids of human anti-P antibody with IgG1 and kappa chain based on the human hybridoma cell line.
GUO Zhonghui +4 more
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Fusion to green fluorescent protein improves expression levels of Theileria parva sporozoite surface antigen p67 in insect cells [PDF]
, 2002 East Coast fever (ECF) is a fatal disease of cattle caused by the protozoan parasite Theileria parva. The development of a subunit vaccine, based on the sporozoite-specific surface antigen p67, has been hampered by difficulties in achieving high-level ...
Kaba, S.A. +4 more
core
Production and Purification of Polyclonal Antibody against Cholera Toxin
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015 BACKGROUND AND OBJECTIVE: Cholera is a debilitating enteric disease, caused by Vibrio cholerae. Cholera toxin is the most important virulence factor in the pathogenesis of Vibrio cholera.
Shahram Nazarian +3 more
doaj
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source