Results 71 to 80 of about 1,379,490 (255)
Diagnostic performance of S. mansoni recombinant antigens antibody detection tests.
, 2023 Diagnostic performance of S. mansoni recombinant antigens antibody detection tests.
Thajasvarie Naicker (3175269) +7 more
core +1 more source
The development of immunoassays for the detection of bovine brucellosis and aflatoxin B1 [PDF]
, 2004 The research discussed in this thesis focuses on the development and characterisation of immunoassays for the detection of aflatoxin Bi (AFBi), a toxic fungal metabolite, and for the diagnosis of bovine brucellosis, a highly contagious disease of cattle ...
Dunne, Lynsey
core +2 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Antibody targeted nanoparticles for imaging and therapy of cancer [PDF]
, 2010 The central hypothesis for this thesis is that antibody-targeted superparamagnetic iron oxide nanoparticles (SPIONs) can be used for diagnosis and therapy of cancer.
Vigor, K.L.
core
Recombinant human preproinsulin expression, purification and reaction with insulin autoantibodies in sera from patients with insulin-dependent diabetes mellitus [PDF]
, 1993 A novel prokaryotic expression vector pGEX-6T was designed for high-level expression of recombinant fusion protein with a histidine-hexapeptide and glutathione-S-transferase at its N-terminus and the recombinant human preproinsulin at its C-terminus ...
Seißler, Jochen +4 more
core +1 more source
The AD946 antibody recognizes a 6xHis-tagged recombinant protein by Western Blot [PDF]
, 2018 The recombinant antibody AD946 detects by Western blot the 6xHis-tagged human myelin oligodendrocyte glycoprotein (MOG)
Lamrabet, Otmane, Jauslin, Tania
core +2 more sources
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
, 2014 Kinetic constants for monoclonal antibody (3B3) and VHH antibody (P2) against the recombinant protein NS1.
Jufang Wang (91185) +7 more
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Conditions for safe and effective ADEPT treatment [PDF]
, 2010 Antibody directed enzyme prodrug therapy (ADEPT) is a drug delivery system developed for the treatment of cancer. ADEPT uses a systemically administered antibody, tethered to an enzyme, to localize enzyme in tumour deposits.
Wilkins, D.K.
core