Results 11 to 20 of about 810,282 (282)

Recombinant Antibodies against Mycolactone

open access: yesToxins, 2019
In the past, it has proved challenging to generate antibodies against mycolactone, the primary lipidic toxin A of Mycobacterium ulcerans causing Buruli ulcer, due to its immunosuppressive properties.
Leslie Naranjo   +7 more
doaj   +4 more sources

Demystified… recombinant antibodies [PDF]

open access: yesJournal of Clinical Pathology, 2004
Recombinant antibodies are important tools for biomedical research and are increasingly being used as clinical diagnostic/therapeutic reagents. In this article, a background to humanised antibodies is given, together with details of the generation of antibody fragments—for example, single chain Fv fragments.
Smith, K.A.   +5 more
openaire   +3 more sources

Recombinant Antibody Technology [PDF]

open access: yesILAR Journal, 1995
36:801-803. Smith, D.B., and K.S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40. Snapper, CM., and J.J. Mond. 1993. Towards a comprehensive view of immunoglobulin class switching. Immunol. Today 14:15-17. Snorasse, T., B. Flamand, G. De Becker, H. Bazin, F.
Alexander E., Karn   +2 more
openaire   +2 more sources

Expression of Recombinant Antibodies [PDF]

open access: yesFrontiers in Immunology, 2013
Recombinant antibodies are highly specific detection probes in research, diagnostics, and have emerged over the last two decades as the fastest growing class of therapeutic proteins. Antibody generation has been dramatically accelerated by in vitro selection systems, particularly phage display.
Frenzel, André   +2 more
openaire   +3 more sources

Isolation and characterization of full-length genes encoding the anti-human CD45 antibody from the hybridoma cell line 16E8-F2

open access: yesHo Chi Minh City Open University Journal of Science - Engineering and Technology, 2022
Though the hybridoma technology has been widely applied in the production of monoclonal antibodies, it has existed some disadvantages including low yield and genetic instability. Therefore, an alternative approach should be taken into account.
Nguyen Quoc Huy   +2 more
doaj   +1 more source

Prediction of Clinical Requirement of Tocilizumab Injection in COVID-19 Patients with High Chest CT Severity Score- A Retrospective Analysis [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Introduction: The ongoing Coronavirus Disease 2019 (COVID19) pandemic has spread rapidly across the globe. Tocilizumab is a recombinant monoclonal antibody to Interleukin-6 (IL-6) receptor. An increasing number of studies across the world is reporting
MEGHA SHETH   +7 more
doaj   +1 more source

Expression of Recombinant Fusion Protein from Local Isolate of Newcastle Disease Virus and Antibody Response to Recombinant Fusion Protein in Broiler Chickens Post-Vaccination

open access: yesJournal of the Indonesian Tropical Animal Agriculture, 2020
This research aimed to express and purify the recombinant Fusion (F) protein of Newcastle Disease Virus (NDV) from a local isolate in Galur, Kulon Progo, Indonesia (0663/04/2013) from recombinant vector plasmid pBT7-N-His F, and to study the antibody ...
R.W. Astuti, N. Wijayanti, A. Haryanto
doaj   +1 more source

Development of a Novel Anti-EpCAM Monoclonal Antibody for Various Applications

open access: yesAntibodies, 2022
The epithelial cell adhesion molecule (EpCAM) is a cell surface glycoprotein, which is widely expressed on normal and cancer cells. EpCAM is involved in cell adhesion, proliferation, survival, stemness, and tumorigenesis.
Guanjie Li   +6 more
doaj   +1 more source

Cell growth inhibition and apoptotic effects of a specific anti-RTFscFv antibody on prostate cancer, but not glioblastoma, cells [version 1; referees: 2 approved, 1 approved with reservations]

open access: yesF1000Research, 2017
Background: Single chain antibody (scFv) has shown interesting results in cancer immunotargeting approaches, due to its advantages over monoclonal antibodies.
Foroogh Nejatollahi   +2 more
doaj   +1 more source

Generation of an Ovomucoid-Immune scFv Library for the Development of Novel Immunoassays in Hen’s Egg Detection

open access: yesFoods, 2023
Hen’s egg allergy is the second most common food allergy among infants and young children. The possible presence of undeclared eggs in foods poses a significant risk to sensitized individuals. Therefore, reliable egg allergen detection methods are needed
Santiago Rodríguez   +7 more
doaj   +1 more source

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