Results 151 to 160 of about 332,084 (209)

The TRIM-cancer paradox: BCG as a programmable vaccine platform and a mechanistic probe for rational immunotherapy design. [PDF]

Front Immunol
Pleshkan VV, Kondratyeva LG, Zinovyeva MV, Bezborodova OA, Alekseenko IV, Shegay PV, Kaprin AD.   +6 more
europepmc   +1 more source

Construction of Recombinant <i>Mycobacterium smegmatis</i> Expressing the Pro-Apoptotic Protein BIK and Its Impact on Macrophage Apoptosis. [PDF]

Pathogens
Pang Y, Bi J.
europepmc   +1 more source

Engineering internally his-tagged ESX secretion system fusion antigens for tuberculosis nanoparticle vaccines. [PDF]

J Biol Chem
Hsu WL, Jiao Y, Huang WC, Tran KN, Troyer BT, Hvasta M, Kuhlman B, Obregon-Henao A, Lovell JF.   +8 more
europepmc   +1 more source

The Cyclic Di-GMP Receptor HpoR Modulates Mycobacterial Multidrug Susceptibility by Regulating IniBAC-Mediated Envelope Permeability. [PDF]

Microorganisms
Liu X, Ling X, Wang K, Zheng J, Li H, Guo M, Ou Y, Lu J, Li W.   +8 more
europepmc   +1 more source

BCG overexpressing Ag85B reprograms host immune response through coordinated transcriptional networks. [PDF]

Front Immunol
Chauhan V, Kumar R, Veerapandian R, Ramos EI, Jagannath C, Gadad SS, Dhandayuthapani S.   +6 more
europepmc   +1 more source

Updated oncolytic viruses for the treatment of bladder cancer: a systematic review. [PDF]

Iran J Microbiol
Khatami F, Mohammadi A, Azadmanesh K, Deyhimfar R, Ghajar HA, Nikoofar P, Aghamir SMK.   +6 more
europepmc   +1 more source

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Recombinant BCGs for tuberculosis and bladder cancer

Vaccine, 2021
Bacillus Calmette-Guérin (BCG) vaccine is an attenuated live strain of Mycobacterium bovis. It may be the most widely used vaccine in human history and is the only licensed human tuberculosis (TB) vaccine available. Despite its excellent safety history, a century of use in global vaccination programs, and its significant contribution to reducing TB ...
Alok K. Singh, Geetha Srikrishna, Trinity J. Bivalacqua, William R. Bishai   +3 more
openaire   +2 more sources

Recombinant BCG Vaccine Candidates

Current Molecular Medicine, 2007
Given the variable protective efficacy provided by Mycobacterium bovis BCG (Bacillus Calmette-Guérin), there is a concerted effort worldwide to develop better vaccines that could be used to reduce the burden of tuberculosis. Recombinant BCG (rBCG) are vaccine candidates that offer some potential in this area.
Rogelio, Hernàndez-Pando, Mauricio, Castañòn, Clara, Espitia, Yolanda, Lopez-Vidal   +3 more
openaire   +2 more sources

Improved protection by recombinant BCG

Microbes and Infection, 2005
Mycobacterium bovis bacille Calmette Guérin (BCG) is one of the most widely used live vaccines. Technologic advancement in genome manipulation enables the construction of recombinant BCG (rBCG) strains, which can be employed as highly immunogenic vaccines against tuberculosis with improved safety profile.
Nasser Eddine, A., Kaufmann, S.
openaire   +3 more sources