Results 1 to 10 of about 577,747 (248)
Design of an in vivo cleavable disulfide linker in recombinant fusion proteins [PDF]
BioTechniques, 2010 In order to achieve optimal biological activity and desired pharmacokinetic profiles, a dithiocyclopeptide linker was designed for in vivo release of protein domains from a recombinant fusion protein.
Xiaoying Chen +3 more
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Simplified ELISA for Detecting Antibodies to Recombinant Fusion Proteins
BioTechniques, 1997 Sergio Carmona +2 more
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Osteoinductive recombinant silk fusion proteins for bone regeneration [PDF]
Acta Biomaterialia, 2017 Protein polymers provide a unique opportunity for tunable designs of material systems due to the genetic basis of sequence control. To address the challenge of biomineralization interfaces with protein based materials, we genetically engineered spider silks to design organic-inorganic hybrid systems.
Dinjaski, N +5 more
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Pharmacokinetics of recombinant bifunctional fusion proteins [PDF]
Expert Opinion on Drug Metabolism & Toxicology, 2012 The development of biotechnology has enabled the creation of various recombinant fusion proteins as a new class of biotherapeutics. The uniqueness of fusion proteins lies in their ability to fuse two or more protein domains, providing vast opportunities to generate novel combinations of functions.
Xiaoying Chen +2 more
openaire +4 more sources
Production of recombinant SARS-COV-2 proteins and diphtheria toxoid CRM197-based fusion [PDF]
The Ukrainian Biochemical Journal, 2021 The quickly emerged global COVID-19 pandemic raised a desperate need in the development of protecting vaccines targeting this disease. Therefore, a generation of effective producers of recombinant SARS-CoV-2 proteins became an urgent task.
O. I. Krynina +10 more
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PLoS ONE, 2022 Although recombinant proteins are widely used in biotechnology and pharmaceutical industries, improving their solubility and stability is often a challenging issue.
Eri Morimoto +2 more
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Frontiers in Plant Science, 2022 Plants have long been considered a cost-effective platform for recombinant production. A recently recognized additional advantage includes the low risk of contamination of human pathogens, such as viruses and bacterial endotoxins. Indeed, a great advance
Shi-Jian Song +4 more
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Macromolecular and Solution Properties of the Recombinant Fusion Protein HUG
Biomacromolecules, 2022 The recombinant fusion protein HELP-UnaG (HUG) is a bifunctional product that exhibits human elastin-like polypeptide (HELP)-specific thermal behavior, defined as a reverse phase transition, and UnaG-specific bilirubin-dependent fluorescence emission. HUG provides an interesting model to understand how its two domains influence each other's properties.
Sist, Paola +3 more
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Refinement of the Fusion Tag PagP for Effective Formation of Inclusion Bodies in Escherichia coli
Microbiology Spectrum, 2023 Methods for efficient insoluble protein production require further exploration. PagP, an Escherichia coli outer membrane protein with high β-sheet content, could function as an efficient fusion partner for inclusion body-targeted expression of ...
Xuefeng Li +6 more
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Immunocontraceptive potential of a GnRH receptor-based fusion recombinant protein [PDF]
Journal of Genetic Engineering and Biotechnology, 2021 The management of stray dog population has been of utmost importance due to their overpopulation, increase in dog bites incidence, and rabies. Contraceptive vaccines, a non-surgical alternative to spaying and neutering are viewed as a valuable option for the management of dog population.
Nathaniel Philip Sandam +2 more
openaire +4 more sources