Results 171 to 180 of about 75,705 (253)

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

Journal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia, Medha Noopur, Ishana Bhattacharya, Bhaskar Chandra Sahoo, Mritunjay Kasera, Naga Jyothi Pullagurla, Smritikana Dutta, Guizhen Liu, Gabriel Schaaf, Henning Jessen, Debabrata Laha, Souvik Bhattacharjee, Saikat Bhattacharjee   +12 more
wiley   +1 more source

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, EarlyView.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source

Effect of Recombinant Human Growth Hormone (rhGH) Use on Genetic Methylation Patterns and Their Relationship with Body Composition in Small-for-Gestational-Age (SGA) Newborns. [PDF]

Biomedicines
Velásquez JMA, Vásquez Trespalacios EM, Urrego R, Arroyave Toro MC, Montilla Velásquez MDP, Soto CMD, Vélez JCZ, Jaramillo Henríquez V, Flórez JES, Monroy FP, Palacio Mosquera HA, Vélez Gómez S, Pelaez Sánchez RG.   +12 more
europepmc   +1 more source

Natural variation in the promoter of OsPDX1.2 enhances vitamin B6 accumulation and cold tolerance in rice

Journal of Integrative Plant Biology, EarlyView.
Allelic variation in the promoter of the pyridoxal phosphate synthase OsPDX1.2 caused variation in the ACE‐box cis‐elements, resulting in differing OsPDX1.2 expression due to differences in binding affinity between the OsbZIP18 transcriptipn factor and the ACE‐box, contributing to variation in vitamin B6 levels and cold tolerance among rice varieties ...
Bi Wang, Qiu Yi Wang, Wen Jie Shi, Rong Hui Li, Xu Dong Zhang, Li Ping Wang, Shi Jia Xia, Kai Xi Chen, Jun Jie Zhou, Yang Yang Sun, Jing He, Alisdair R. Fernie, Ying Chun Han, Jun Zhou Li, Yu Heng Shi, Xian Qing Liu, Yuan Yuan Zhang, Jie Luo, Cheng Jin   +18 more
wiley   +1 more source

Two cases of autosomal dominant familial short stature associated with <i>COL11A2</i> gene variant and the therapeutic response to recombinant human growth hormone. [PDF]

Transl Pediatr
Bao P, Jiang L, Liu G, Li Y, Chen X, Wang M.   +5 more
europepmc   +1 more source

Characterisation of human hair follicle development

Journal of Anatomy, EarlyView.
Schematic of hair follicle development in human skin. Hair follicle primordia of similar sizes, but different densities, are laid out across the skin. The distinction between terminal and vellus hair sites is not obvious at early stages of hair follicle development.
Zoe R. Sudderick, James D. Glover, Cameron Batho‐Samblas, Barbara Bo‐Ju Shih, Denis J. Headon   +4 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

An improved reporter gene assay for evaluating the biological activity of recombinant human growth hormone. [PDF]

J Pharm Anal
Zhang X, Li H, Huang Y, Lv P, Wang L, Xu K, Li Y, Hu X, Sun Y, Liang CG, Li J.   +10 more
europepmc   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

A retrospective study of recombinant human growth hormone in the treatment of school-aged pediatric patients with idiopathic short stature. [PDF]

Medicine (Baltimore)
Chen Y, Li YH, Zhang XR.
europepmc   +1 more source