Results 181 to 190 of about 75,972 (251)

A Phase 2 Study of PEGylated Recombinant Human Growth Hormone for 52 Weeks in Short Children Born Small for Gestational Age in China. [PDF]

Clin Endocrinol (Oxf)
Luo X, Hou L, Zhong Y, Zhao S, Chen X, Dong Q, Du H, Lu H, Yang Y, Wu X, Luo F, Chen R, Xu Z, Ma Y, Song W, Feng M, Gu X, Qiu W.   +17 more
europepmc   +1 more source

Revisiting the Molecular Roadmap for Sugar Crops: Genome Reading, Trait Writing and Variety Redesigning

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sugar crops, including but not limited to sugarcane, sugar beet, sweet sorghum and stevia, are major sources of sugar production in the world. However, conventional breeding approaches, limited by long breeding cycles, low efficiency and restricted capacity to improve complex traits in sugar crops, are increasingly insufficient to address the ...
Peilin Wang, Qibin Wu, Wenzhi Wang, Prakash Lakshmanan, Yangrui Li, Khushi Muhammad, Yuguang Wang, Youxiong Que   +7 more
wiley   +1 more source

Optimal final adult height achieved by low-dose recombinant human growth hormone therapy. [PDF]

Asian Biomed (Res Rev News)
Saengkaew T, Aroonparkmongkol S, Wacharasindhu S.   +2 more
europepmc   +1 more source

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

Plant Biotechnology Journal, EarlyView.
ABSTRACT Indoor vertical farming (VF) offers practical advantages for the cultivation of plant protein bio‐factories including plant uniformity, product consistency, water/nutrient recycling and production cycles on a year‐round basis. Much progress has been achieved toward the development of innovative systems for artificial lighting, automated ...
Béatrice Giroux, Kristina LeBreux, Louis Feyzeau, Marie‐Claire Goulet, Charles Goulet, Dominique Michaud   +5 more
wiley   +1 more source

Cell‐Specific Expression and Cellular Compartmental Regulation in Camptothecin Biosynthesis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant secondary metabolites such as monoterpenoid indole alkaloids (MIAs) show tightly regulated biosynthesis and accumulation in specific organelles of distinct cell types. However, the cell‐specific expression patterns of anticancer MIA camptothecin biosynthetic genes in Ophiorrhiza pumila and the regulatory mechanisms of camptothecin ...
Xiaolong Hao, Yinkai Yang, Tiantian Chen, Xiaoxuan Fan, Yiqing Peng, Qingyan Ruan, Qin Zhou, Fanghao Liu, Jiayi He, Yongpeng Li, Yue Feng, Jiyan Qi, Guoyin Kai   +12 more
wiley   +1 more source

Therapeutic efficacy of recombinant human growth hormone in children with different etiologies of dwarfism from a pharmacoeconomic point of view. [PDF]

Medicine (Baltimore)
Ma Y, Sheng J, Wang L, Zhang Y, Liu L.
europepmc   +1 more source

Spatially Resolved ABA Signalling Reveals Dual Role in Tomato Yield

Plant Biotechnology Journal, EarlyView.
ABSTRACT Abscisic acid (ABA) is a central hormonal regulator of plant adaptation to stress and developmental progression. However, its contribution to agronomic traits such as yield remains unclear due to the pleiotropic nature of ABA signalling. To disentangle distinct physiological functions of ABA, we employed a receptor‐specific gain‐of‐function ...
Fu‐An Wen, Fu‐Dong Mai, Ji‐Bin Xiao, Hong Zhang, Xuan Zhou, Xin‐Yu Yang, Yelena Sterlin, David Karpovsky, Ke‐Ting Li, Juan Wang, Jia Liu, Shi‐Hao Su, Assaf Mosquna, Yu‐Fei Sun   +13 more
wiley   +1 more source

Natural Variation in GmSL20 Improves Seed Size and Quality in Soybean

Plant Biotechnology Journal, EarlyView.
ABSTRACT Seed size plays an important role in determining crop yield, yet the genetic mechanisms underlying the regulation of this agronomic trait remain incompletely understood in soybean. Here, we perform a genome‐wide association study mapping with seed length variations and identify a major quantitative trait locus (QTL) on chromosome 20, named ...
Yuechuan Luo, Zongbiao Duan, Juxu Li, Zhou Zhu, Tong Wu, Dan Li, Yangping Liu, Liangwei Xu, Hao Wen, Yanting Shen, Shulin Liu, Qingtian Li, Zhixi Tian   +12 more
wiley   +1 more source

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

Targeted Modulation of Eukaryotic Release Factor 1 (OseRF1) by an RNA Aptamer Enhances Drought Adaptation in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought stress severely restricts rice productivity, necessitating strategies to enhance stress resilience. Here, we identify translation termination as a tunable regulatory node for stress adaptation. Using 25 rounds of SELEX, we isolated RTAR, an RNA aptamer that binds the rice eukaryotic release factor 1 (OseRF1) with nanomolar affinity ...
Shuangfeng Dai, Mingming Chen, Haomin Chen, Yuantao Ye, Hong Huang, Renrong Zhang, Zhenyu Guo, Yongxiang Huang   +7 more
wiley   +1 more source