Results 21 to 30 of about 2,765,447 (281)
Optimising expression and extraction of recombinant proteins in plants
Frontiers in Plant Science, 2022 Recombinant proteins are of paramount importance for research, industrial and medical use. Numerous expression chassis are available for recombinant protein production, and while bacterial and mammalian cell cultures are the most widely used, recent ...
Ryan J. Coates +2 more
doaj +3 more sources
Hands‐free from inoculation to harvest: Microbial fermentation with multivariate model to automate induction of recombinant protein expression [PDF]
Biotechnol ProgJennifer Reid +6 more
openalex +2 more sources
A novel knock out strategy to enhance recombinant protein expression in Escherichia coli [PDF]
Microb Cell Fact, 2020 Ashish K. Sharma +4 more
openalex +2 more sources
Ramping Recombinant Protein Expression in Bacteria. [PDF]
Biochemistry, 2020 Zahurancik WJ +3 more
europepmc +4 more sources
Optimization of CYP27A1 recombinant protein expression. [PDF]
Protein Expr PurifHuman mitochondrial cytochrome P450 27A1 is a monooxygenase enzyme that oxidizes bile acids and other sterol derivatives. The enzyme plays an important role in sterol metabolism and is a potential target for clinical therapies related to metabolic conditions and certain cancers.
Papa JE +5 more
europepmc +3 more sources
Frontiers in Bioengineering and Biotechnology, 2022 Chinese hamster ovary (CHO) cells are currently the most widely used host cells for recombinant therapeutic protein (RTP) production. Currently, the RTP yields need to increase further to meet the market needs and reduce costs.
Qin Li +8 more
doaj +1 more source
Molecular Therapy: Oncolytics, 2023 CD47 and its receptor signal regulatory protein α (SIRPα) act as a dominant antiphagocytic, “don’t eat me” signal. Recent studies reveal CD24 as a novel target for cancer immunotherapy by macrophages in ovarian cancer and breast cancer.
Yun Yang +10 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 In recent years, mammalian cells have become the primary host cells for the production of recombinant therapeutic proteins (RTPs). Despite that the expression of RTPs in mammalian cells can be improved by directly optimizing or engineering the expression
Mian Wei +4 more
doaj +1 more source
Advances of Glycometabolism Engineering in Chinese Hamster Ovary Cells
Frontiers in Bioengineering and Biotechnology, 2021 As the most widely used mammalian cell line, Chinese hamster ovary (CHO) cells can express various recombinant proteins with a post translational modification pattern similar to that of the proteins from human cells.
Huan-Yu Zhang +5 more
doaj +1 more source
The Effect of microRNA on the Production of Recombinant Protein in CHO Cells and its Mechanism
Frontiers in Bioengineering and Biotechnology, 2022 Recombinant protein production by mammalian cells is the initial step in the manufacture of many therapeutic proteins. Chinese hamster ovary (CHO) cells are the most common host system to produce recombinant therapeutic proteins (RTPs).
Hui-Ning Liu +7 more
doaj +1 more source