Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production [PDF]
Although many recombinant proteins have been produced in seeds at high yields without adverse effects on the plant, endoplasmic reticulum (ER) stress and aberrant localization of endogenous or recombinant proteins have also been reported.
Arcalis, Elsa+13 more
core +2 more sources
Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems [PDF]
Serine proteases, cysteine proteases, and matrix metalloproteinases (MMPs) are involved in cancer cell invasion and metastasis. Recently, a recombinant bifunctional inhibitor (chCysuPA(19-31)) directed against cysteine proteases and the urokinasetype ...
Brew K.+11 more
core +2 more sources
Background Mycoplasma hyopneumoniae, the primary pathogen responsible for porcine enzootic pneumonia, reduces average daily weight gain and causes substantial economic losses to the pig industry worldwide.
Yaru Ning+7 more
doaj +1 more source
Accelerated Partial Breast Irradiation: A New Strategy for Early-Stage Breast Cancer
Background: Accelerated partial breast irradiation (APBI) is defined as applying high doses of radiation with a shorter interval to the lumpectomy cavity in the setting of breast-conserving therapy for early-stage breast cancer.
Mahdi Aghili+3 more
doaj +1 more source
The demand for recombinant proteins is rising dramatically, and effective production systems are currently being developed. The production of recombinant proteins in plants is a promising approach due to its low cost and low risk of contamination of the ...
Masatake Kanai+5 more
doaj +1 more source
Flexible approaches are required for successful production of recombinant proteins in plants
Production of recombinant proteins has increased significantly due to the ever-increasing demand in research laboratories, medical fields, and agriculture.
Nilufer Gun, Tarlan Mamedov
doaj +1 more source
Recombinant canine single chain insulin analogues: Insulin receptor binding capacity and ability to stimulate glucose uptake [PDF]
Virtually all diabetic dogs require exogenous insulin therapy to control their hyperglycaemia. In the UK, the only licensed insulin product currently available is a purified porcine insulin preparation.
Angela L. Holder+23 more
core +1 more source
Recombinant protein expression in biofilms
Biofilm research is usually focused on the prevention or control of biofilm formation. Recently, the significance of the biofilm mode of growth in biotechnological applications received increased attention. Since biofilm reactors show many advantages over suspended cell reactors, especially in their higher biomass density and operational stability ...
Luciana C. Gomes+3 more
openaire +3 more sources
Design and expression of TolC as a recombinant protein vaccine against Shigella flexneri and evaluation of immunogenic response in mice [PDF]
Background: Shigella is one of the major cause of dysenteric diarrhea, which is known shigelosis. Shigelosis causes 160,000 deaths annually of diarrheal disease in a global scale especially children less than 5 years old. No licensed vaccine is available against shigelosis, therefore, efforts for develop an effective and safe vaccine against shigella ...
arxiv
Glycolytic enzymes - novel carbohydrate binding proteins for glycoprotein analysis [PDF]
•The cloning, expression, purification and characterisation of recombinant prokaryotic glycolytic enzymes •The mutagenesis of prokaryotic glycolytic enzymes to generate novel recombinant carbohydrate binding proteins •The characterisation of the ...
Clarke, Paul A.+3 more
core