Results 61 to 70 of about 2,626,165 (307)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Anticancer and Antibacterial Efficacy of Nanoemulsion of Matricaria chamomilla Essential Oil [PDF]

Nanomedicine Research Journal
Conclusions: Cancers and bacterial infections are significant global public health challenges and economic issues. Nanostructures containing essential oils have been considered a suitable alternative as therapeutic agents.
Zahra Ghorbani, Hiva Alipanah, Sedighe Kolivand, Elham Zarenezhad, Mahbod Fazlali, Mahmoud Osanloo   +5 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Repurposing the anti-parasitic agent pentamidine for cancer therapy; a novel approach with promising anti-tumor properties

Journal of Translational Medicine
Pentamidine (PTM) is an aromatic diamidine administered for infectious diseases, e.g. sleeping sickness, malaria, and Pneumocystis jirovecii pneumonia. Due to similarities of cellular mechanisms between human cells and such infections, PTM has also been ...
Nima Rastegar-Pouyani, Mohammad Amin Farzin, Jaber Zafari, Mohadeseh Haji Abdolvahab, Shokoufeh Hassani   +4 more
doaj   +1 more source

DEVELOPMENT OF THE VACCINE BASED ON THE RECOMBINANT ANTIGENS OF PSEUDOMONAS AERUGINOSA

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. The aim is obtaining, investigation and selection of recombinant antigens for inclusion theirs into the against Pseudomonas vaccine. Materials and methods. The genes encoding of the outer  membrane proteins F, L and I and Exotoxin A were synthesized
N. A. Mihailova, E. M. Zimina, A. V. Soldatenkova, A. A. Kaloshin   +3 more
doaj   +1 more source

Protective vaccination in the horse against _Streptococcus equi_ with recombinant antigens [PDF]

, 2009
_Streptococcus equi_ subspecies _equi_ (_S. equi_) is a clonal, equine host-adapted pathogen of global importance that causes a highly contagious suppurative lymphodendopathy of the head and neck, more commonly known as Strangles.
Carl Robinson, Ken Smith, Margareta Flock, Andrew Waller, Jan-Ingmar Flock, Lars Frykberg, Bengt Guss   +6 more
core  

Recombinant BB0562 proteins.

, 2021
Purified wild-type (WT) recombinant Nus-BB0562, single (S34A; S34T; S58A; S58T) and double mutant (S34A, S58A; S34T, S58T) proteins and Nus alone, were separated by SDS-PAGE. Proteins were visualized by Coomassie blue staining (CB). Molecular weights are
Travis J. Jewett (11307816), Hunter W. Kuhn (11307801), Brandee L. Stone (11307810), Carlos Flores Avile (10679261), Mollie W. Jewett (11307819), Amanda G. Lasseter (11307804), Darrin R. Akins (11307813), Philip P. Adams (11307807)   +7 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Optimization of a recombinant BlaR-CTD protein formulation using the response surface methodology

Journal of Biological Engineering
The sequence of a carboxy-terminal of the β-lactam sensor-transducer protein (BlaR-CTD) from Bacillus licheniformis ATCC14580 was extracted from US7745193B2 patent and expressed in E. coli using pColdI vector as a soluble His-tag recombinant protein.
Mohadeseh Haji Abdolvahab, Mojdeh Safari, Farkhonde Hasannejad, Nika Asefi, Alireza Salimi, Mahboobeh Nazari   +5 more
doaj   +1 more source

Immunodiagnostic Value of Echinococcus Granulosus Recombinant B8/1 Subunit of Antigen B [PDF]

Iranian Journal of Immunology, 2017
Background: Cystic echinococcosis (CE), as a chronic parasitic disease, is a major health problem in many countries. The performance of the currently available serodiagnostic tests for the diagnosis of CE is unsatisfactory.
Amir Savardashtaki, Bahador Sarkari, Farzane Arianfar, Zohreh Mostafavi-Pour   +3 more
doaj