Results 21 to 30 of about 516,295 (311)

A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve. [PDF]

open access: yes, 2018
open6siopenPatruno, M; Melotti L.; Gomiero, C; Sacchetto, R; Topel, O; Martinello, T.Patruno, M; Melotti, Luca; Gomiero, C; Sacchetto, R; Topel, O; Martinello ...

core   +1 more source

The Effect of microRNA on the Production of Recombinant Protein in CHO Cells and its Mechanism

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Recombinant protein production by mammalian cells is the initial step in the manufacture of many therapeutic proteins. Chinese hamster ovary (CHO) cells are the most common host system to produce recombinant therapeutic proteins (RTPs).
Hui-Ning Liu   +7 more
doaj   +1 more source

Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]

open access: yes, 2017
The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria   +5 more
core   +1 more source

Is there NO treatment for severe sepsis? [PDF]

open access: yes, 2008
Sepsis is a systemic inflammatory response syndrome in the presence of suspected or proven infection, and it may progress to or encompass organ failure (severe sepsis) and hypotension (septic shock).
Bredan, Amin, Cauwels, Anje
core   +2 more sources

Engineered Recombinant Protein Production Systems Originated from Escherichia coli

open access: yesTrends in Peptide and Protein Sciences, 2019
Selection of a suitable host strain is an important step in recombinant production of heterologous proteins. As the prokaryotic systems and especially Escherichia coli (E.
Javad Ranjbari
doaj   +1 more source

Overexpressing CrePAPS Polyadenylate Activity Enhances Protein Translation and Accumulation in Chlamydomonas reinhardtii

open access: yesMarine Drugs, 2022
The alga Chlamydomonas reinhardtii is a potential platform for recombinant protein expression in the future due to various advantages. Dozens of C. reinhardtii strains producing genetically engineered recombinant therapeutic protein have been reported ...
Quan Wang   +10 more
doaj   +1 more source

cDNA Cloning of a Bovine Insulin-like growth factor-1 from Egyptian Buffalos and Expression of its Recombinant Protein in Escherichia coli [PDF]

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020
Insulin-like growth factor-1 (IGF-1) is regarded as a crucial clinically significant therapeutic agent against several pathological conditions. Recently, recombinant DNA (rDNA) technology has enabled the production of many drugs of rDNA-origin including ...
Mourad A.M. Aboul-Soud
doaj   +1 more source

Reducing Campylobacter jejuni colonization in broiler chickens by in-feed supplementation with hyperimmune egg yolk antibodies [PDF]

open access: yes, 2019
Campylobacter infections sourced mainly to poultry products, are the most important bacterial foodborne zoonoses worldwide. No effective measures to control these infections in broiler production exist to date.
Canessa, Stefano   +8 more
core   +1 more source

PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPAR?? at Ser273 [PDF]

open access: yes, 2020
Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a master regulator of adipose tissue biology. In obesity, phosphorylation of PPAR gamma at Ser273 (pSer273) by cyclin-dependent kinase 5 (CDK5)/extracellular signal-regulated kinase (ERK ...
Choi, Jang Hyun   +11 more
core   +1 more source

A Review on Empirical Approach to Therapeutic Recombinant Protein Production Factories: Applications, Pharmacokinetics and Challenges

open access: yesJournal of Bioresource Management, 2022
Major portion of the proteins in a cell refers to their critical roles in metabolism of the living body. Proteins dysfunction results in the severe disorders which need to be treated in time.
Zahra Naz, Ambreen Kanwal, Asima Tayyeb
doaj  

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