Results 11 to 20 of about 404,123 (293)

Cnidarian toxins: omics approaches and recombinant proteins [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases
Cnidarian venom toxins have attracted increasing interest due to their remarkable molecular diversity and pharmacological potential. Omics technologies - such as genomics, transcriptomics, proteomics, and metabolomics - have facilitated the ...
Jesús Eduardo Vega-Tamayo, Esteban de Jesús Alcantar-Orozco, Ramiro Arturo Mendoza-Ramírez, Luna Gabriela Silva-Díaz, Jorge Alberto Aguilar-Salazar, Diego Hermilo Salvador-Aguilar, Alejandra Rojas-Molina   +6 more
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Measurement over 1 Year of Neutralizing Antibodies in Cattle Immunized with Trivalent Vaccines Recombinant Alpha, Beta and Epsilon of Clostridium perfringens

Toxins, 2021
The alpha (CPA), beta (CPB) and epsilon (ETX) toxins of Clostridium perfringens are responsible for causing diseases that are difficult to eradicate and have lethal potential in production animals. Vaccination of herds is still the best control strategy.
Cleideanny C. Galvão, José D. Barbosa, Carlos M. C. Oliveira, Denis Y. Otaka, Paulo R. O. Silva, Marcos R. A. Ferreira, Clóvis Moreira Júnior, Fabricio R. Conceição, Felipe M. Salvarani   +8 more
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Exploring the Utility of ssDNA Aptamers Directed against Snake Venom Toxins as New Therapeutics for Snakebite Envenoming

Toxins, 2022
Snakebite is a neglected tropical disease that causes considerable death and disability in the tropical world. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterised by
Nessrin Alomran, Raja Chinnappan, Jaffer Alsolaiss, Nicholas R. Casewell, Mohammed Zourob   +4 more
doaj   +1 more source

Acknowledgment to Reviewers of Toxins in 2020

, 2021
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Toxins maintains its standards for the high quality of its published papers [...
Toxins Editorial Office Toxins Editorial Office
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Cloning and Expression of a Fusion Protein Containing Highly Epitopic Regions of Clostridium perfringens Epsilon Toxin and Clostridium novyi Alpha Toxin [PDF]

Journal of Cell and Molecular Research, 2021
Clostridium perfringens and novyi species are two important toxin-producing pathogens which pose a risk to the livestock health. Epsilon and alpha toxins are major toxins of these two pathogens, respectively. Advances in current vaccine industrialization
Mohsen Mehrvarz, Mohsen Fathi Najafi, Taghi Zahraei Salehi, Behjat Majidi   +3 more
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The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]

, 2008
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Morris, James A., Telford, David R., Lauder, Robert M., Harrison, Linda M.   +3 more
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Bacteria-derived chimeric toxins as potential anticancer agents

Frontiers in Oncology, 2022
Cancer is one of the major causes of death globally, requiring everlasting efforts to develop novel, specific, effective, and safe treatment strategies.
Saeed Khoshnood, Hadis Fathizadeh, Hadis Fathizadeh, Foroogh Neamati, Babak Negahdari, Piyush Baindara, Mohd Azmuddin Abdullah, Mohammad Hossein Haddadi   +7 more
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Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockers. [PDF]

PLoS ONE, 2012
The K(v)1.3 voltage-gated potassium channel regulates membrane potential and calcium signaling in human effector memory T cells that are key mediators of autoimmune diseases such as multiple sclerosis, type 1 diabetes, and rheumatoid arthritis.
Raveendra Anangi, Shyny Koshy, Redwan Huq, Christine Beeton, Woei-Jer Chuang, Glenn F King   +5 more
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Phase I clinical study of the recombinant antibody toxin scFv(FRP5)-ETA specific for the ErbB2/HER2 receptor in patients with advanced solid malignomas [PDF]

, 2005
INTRODUCTION: ScFv(FRP5)-ETA is a recombinant antibody toxin with binding specificity for ErbB2 (HER2). It consists of an N-terminal single-chain antibody fragment (scFv), genetically linked to truncated Pseudomonas exotoxin A (ETA).
Wels, Winfried, Sebastian Harder, Sibylle Loibl, Christian Cimpoiasu, Akin Atmaca, Cimpoiasu, C, Elke Jäger, Alexander Knuth, Dirk Jäger, Minckwitz, Gunter von, Neumann, A M, Harder, S, Cimpoiasu, Christian, Antje Neumann, Hövelmann, S, Winfried S Wels, Atmaca, Akin, Knuth, Alexander, Sascha Hövelmann, Abera, A, Abera, Aklil, Maurer, Alexander B., Gunter von Minckwitz, Aklil Abera, Al-Batran, S E, Knuth, A L, Loibl, S G, Hövelmann, Sascha, Jäger, Elke, Jäger, Dirk, Salah-Eddin Al-Batran, Alexander B Maurer, Loibl, Sibylle, Maurer, A B, Manfred Kaufmann, Wels, W S, von Minckwitz, G, Neumann, Antje, Jäger, D, Jäger, E, Atmaca, A, Kaufmann, M, Batran, Salah-Eddin al-, Kaufmann, Manfred, Harder, Sebastian   +44 more
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Targeted Toxins in Brain Tumor Therapy

Toxins, 2010
Targeted toxins, also known as immunotoxins or cytotoxins, are recombinant molecules that specifically bind to cell surface receptors that are overexpressed in cancer and the toxin component kills the cell.
Walter A. Hall, Yan Michael Li
doaj   +1 more source