Results 11 to 20 of about 356,092 (265)

An easy method to generate recombinant pseudorabies virus expressing the capsid protein of Porcine circovirus type 2d

Frontiers in Microbiology, 2023
IntroductionHomologous recombination is an effective way to generate recombinant viruses for vaccine research such as pseudorabies virus (PRV) and adenovirus.
Jingqiang Ren, Jingqiang Ren, Jingqiang Ren, Rachel Madera, Chase Cunningham, Jishu Shi, Lihua Wang   +6 more
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A Novel Neurotoxin Gene ar1b Recombination Enhances the Efficiency of Helicoverpa armigera Nucleopolyhedrovirus as a Pesticide by Inhibiting the Host Larvae Ability to Feed and Grow. [PDF]

PLoS ONE, 2015
A recombinant Helicoverpa armigera nucleopolyhedrovirus (HearNPV), Ar1b-HearNPV, was constructed and identified as an improved bio-control agent of Helicoverpa armigera larvae.
Huan Yu, Jiao Meng, Jian Xu, Tong-Xian Liu, Dun Wang   +4 more
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A novel recombinant pseudorabies virus expressing parvovirus VP2 gene: Immunogenicity and protective efficacy in swine

Virology Journal, 2011
Background Porcine parvovirus (PPV) VP2 gene has been successfully expressed in many expression systems resulting in self-assembly of virus-like particles (VLPs) with similar morphology to the native capsid.
Chen Dishi, Shi Qian, Luo Yan, Yan Qigui, Xu Zhiwen, Guo Wanzhu, Chen Yang, Zhu Ling, Wang Xiaoyu   +8 more
doaj   +1 more source

Protective immunity and safety of a genetically modified influenza virus vaccine. [PDF]

PLoS ONE, 2014
Recombinant influenza viruses are promising viral platforms to be used as antigen delivery vectors. To this aim, one of the most promising approaches consists of generating recombinant viruses harboring partially truncated neuraminidase (NA) segments. To
Rafael Polidoro Alves Barbosa, Ana Paula Carneiro Salgado, Cristiana Couto Garcia, Bruno Galvão Filho, Ana Paula de Faria Gonçalves, Braulio Henrique Freire Lima, Gabriel Augusto Oliveira Lopes, Milene Alvarenga Rachid, Andiara Cristina Cardoso Peixoto, Danilo Bretas de Oliveira, Marco Antônio Ataíde, Carla Aparecida Zirke, Tatiane Marques Cotrim, Érica Azevedo Costa, Gabriel Magno de Freitas Almeida, Remo Castro Russo, Ricardo Tostes Gazzinelli, Alexandre de Magalhães Vieira Machado   +17 more
doaj   +1 more source

Gene Transfer in Rodent Nervous Tissue Following Hindlimb Intramuscular Delivery of Recombinant Adeno-Associated Virus Serotypes AAV2/6, AAV2/8, and AAV2/9

Neuroscience Insights, 2019
Recombinant adeno-associated virus (rAAV) vectors have emerged as the safe vehicles of choice for long-term gene transfer in mammalian nervous system. Recombinant adeno-associated virus–mediated localized gene transfer in adult nervous system following ...
Asad Jan, Mette Richner, Christian B Vægter, Jens R Nyengaard, Poul H Jensen   +4 more
doaj   +1 more source

A thymidine kinase-deleted bovine herpesvirus 5 establishes latent infection but reactivates poorly in a sheep model

Pesquisa Veterinária Brasileira, 2013
The ability of thymidine kinase (tk)-deleted recombinant bovine herpesvirus 5 (BoHV-5tkΔ) to establish and reactivate latent infection was investigated in lambs. During acute infection, the recombinant virus replicated moderately in the nasal mucosa, yet
Gustavo C. Cadore, Marcelo Weiss, Deniz Anziliero, Mário Celso S. Brum, Rudi Weiblen, Eduardo F. Flores   +5 more
doaj   +1 more source

Vaccine platform recombinant measles virus [PDF]

Virus Genes, 2017
The classic development of vaccines is lengthy, tedious, and may not necessarily be successful as demonstrated by the case of HIV. This is especially a problem for emerging pathogens that are newly introduced into the human population and carry the inherent risk of pandemic spread in a naïve population.
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Mapping the sites of latency and reactivation by bovine herpesvirus 5 (BoHV-5) and a thymidine kinase-deleted BoHV-5 in lambs

Pesquisa Veterinária Brasileira, 2013
A thymidine kinase (tk)-deleted bovine herpesvirus 5 (BoHV-5tkΔ) was previously shown to establish latent infection and reactivate - even poorly - in a sheep model (Cadore et al. 2013). As TK-negative alphaherpesviruses are unlike to reactivate in neural
Gustavo C. Cadore, Gian Marcon, Mario Celso Sperotto Brum, Rudi Weiblen, Eduardo F. Flores   +4 more
doaj   +1 more source

Possible repair of UV-damaged Spodoptera littoralis nucleopolyhedrovirus DNA via generation of mutant carrying photolyase gene with DNA repair activity

Egyptian Journal of Biological Pest Control, 2023
Background Baculoviruses can be inactivated by ultraviolet (UV) light, which limits their application as an efficient biopesticide. In an attempt to enhance virus resistance to UV inactivation, a photolyase gene, isolated from Spodoptera litura ...
Wael Elmenofy, Lamis Gomaa, Nourhan Albeltagy, Norhan Yasser, Alshaimaa Mahmoud, Engy Osman   +5 more
doaj   +1 more source

Recombination with Herpes Simplex Virus [PDF]

Journal of General Microbiology, 1955
Summary: The behaviour of six strains of herpes simplex virus was studied. Marked differences were noted in the type of lesion formed and the rate of attachment when the strains were inoculated on to the chorio-allantois, and in the behaviour of strains inoculated intracerebrally into mice or on to the cornea of the rabbit.
openaire   +2 more sources