Results 121 to 130 of about 10,769 (161)

Strand Selection by the Tyrosine Recombinases

2005
Publisher Summary This chapter focuses on four tyrosine recombinases for which there is a wealth of biochemical and structural data. This chapter reviews the biochemical and structural findings for each of these enzymes. This chapter also examines the factors that influence strand selection and consider the possible function of strand selection in ...
Linda, Lee, Paul D, Sadowski
openaire   +2 more sources

Safety Assessment of Cre Recombinase

Journal of Agricultural and Food Chemistry, 2006
Cre recombinase, when used as a tool in agricultural biotechnology, can precisely excise DNA sequences that may be useful in the introduction of a new trait but are not needed in the commercial product. Although the cre genetic material would not be present in the final product, the present studies were performed to assess the safety of Cre recombinase
Ronald E, Hileman, Heather K S, Bonner, Terry A, Kaempfe, Bruce G, Hammond, Kevin C, Glenn   +4 more
openaire   +2 more sources

Genome Engineering with Custom Recombinases

2014
Site-specific recombinases are valuable tools for myriad basic research and genome engineering applications. In particular, hybrid recombinases consisting of catalytic domains from the resolvase/invertase family of serine recombinases fused to Cys2-His2 zinc-finger or TAL effector DNA-binding domains are capable of introducing targeted modifications ...
Thomas, Gaj, Carlos F, Barbas
openaire   +2 more sources

Regulation and Evolution of the RAG Recombinase

2015
The modular, noncontiguous architecture of the antigen receptor genes necessitates their assembly through V(D)J recombination. This program of DNA breakage and rejoining occurs during early lymphocyte development, and depends on the RAG1 and RAG2 proteins, whose collaborative endonuclease activity targets specific DNA motifs enriched in the antigen ...
Grace, Teng, David G, Schatz
openaire   +2 more sources

Harnessing orthogonal recombinases to decipher cell fate with enhanced precision

Trends in Cell Biology, 2022
Bin Zhou, Kathy O Lui, Xiuxiu Liu
exaly  

Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes

Molecular Systems Biology, 2021
Orsolya Barabás, Alex Bateman, Georgy Smyshlyaev   +2 more
exaly  

recombinase, n.

2023
openaire   +1 more source

Serine recombinases as tools for genome engineering

Methods, 2011
William Ra Brown, Margaret C M Smith, Nicholas Lee   +2 more
exaly  

Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases

Circulation, 2018
Wenjuan Pu, Bin Zhou, Yi Li
exaly  

Topoisomerases and site-specific recombinases: similarities in structure and mechanism

Critical Reviews in Biochemistry and Molecular Biology, 2010
Wei Yang
exaly