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Recombination: Homologous recombination branches out [PDF]
Current Biology, 2001 Homologous recombination can be divided into three key steps: strand exchange, branch migration and resolution. The identification of a protein complex that catalyses branch migration and Holliday junction resolution argues that the mechanism of homologous recombination is conserved from bacteria to man.
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Pathogens, 2022 Genetic recombination is used as a tool for modifying the composition of poxvirus genomes in both discovery and applied research. This review documents the history behind the development of these tools as well as what has been learned about the processes that catalyze virus recombination and the links between it and DNA replication and repair.
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Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae
Microbiology and Molecular Biology Reviews, 1999 SUMMARY The budding yeast Saccharomyces cerevisiae has been the principal organism used in experiments to examine genetic recombination in eukaryotes.
F. Pâques, J. Haber
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GEN1 promotes common fragile site expression
Cell Reports, 2023 Summary: Our genomes harbor conserved DNA sequences, known as common fragile sites (CFSs), that are difficult to replicate and correspond to regions of genome instability.
Anaid Benitez +6 more
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The coronavirus proofreading exoribonuclease mediates extensive viral recombination
bioRxiv, 2020 Coronaviruses (CoVs) emerge as zoonoses and cause severe disease in humans, demonstrated by the SARS-CoV-2 (COVID-19) pandemic. RNA recombination is required during normal CoV replication for subgenomic mRNA (sgmRNA) synthesis and generates defective ...
J. Gribble +8 more
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Frontiers in Microbiology, 2021 Porcine epidemic diarrhea virus (PEDV) is the major pathogen that causes diarrhea and high mortality in newborn piglets with devastating impact to the pig industry.
Dongliang Li +12 more
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Surface recombination measurements on III–V candidate materials for nanostructure light-emitting diodes [PDF]
, 2000 Surface recombination is an important characteristic of an optoelectronic material. Although surface recombination is a limiting factor for very small devices it has not been studied intensively. We have investigated surface recombination velocity on the
Bhat, R. +9 more
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Recombination by Replication [PDF]
Cell, 1996 The evidence summarized above strongly suggests that E. coli cells deal with exposed double-stranded ends by a process that requires both homologous recombination and DNA replication functions. This process could lead to recombinant formation. Importantly, inhibition of recombination-dependent replication in priA null mutants does not completely block ...
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Recombination and Replication [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 The links between recombination and replication have been appreciated for decades and it is now generally accepted that these two fundamental aspects of DNA metabolism are inseparable: Homologous recombination is essential for completion of DNA replication and vice versa.
Michelle Hawkins +2 more
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RDP3: a flexible and fast computer program for analyzing recombination
Bioinform., 2010 Summary: RDP3 is a new version of the RDP program for characterizing recombination events in DNA-sequence alignments. Among other novelties, this version includes four new recombination analysis methods (3SEQ, VISRD, PHYLRO and LDHAT), new tests for ...
D. Martin +5 more
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