Results 51 to 60 of about 481,827 (299)
Frontiers in Psychiatry, 2010 Although exchange of genetic information by recombination plays an important role in the evolution of viruses, it is not clear how it generates diversity.
Kai Xu, Ruriko Yoshida
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Emerging Infectious Diseases, 2020 We aimed to clarify the epidemiologic and clinical importance of evolutionary events that occurred in carbapenem-resistant Klebsiella pneumoniae (CRKP). We collected 203 CRKP causing bloodstream infections in a tertiary hospital in China during 2013–2017.
Kai Zhou +11 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 Porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) is one of the main pathogens causing porcine reproductive and respiratory syndrome (PRRS).
Qi Sun +6 more
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The Astrophysical Journal, 2000 Under the standard model for recombination of the primeval plasma, and the cold dark matter model for structure formation, recent measurements of the first peak in the angular power spectrum of the cosmic microwave background temperature indicate the spatial geometry of the universe is nearly flat.
P. J. E. Peebles, Wayne Hu, Sara Seager
openaire +2 more sources
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Recombinant Coxsackievirus A2 and Deaths of Children, Hong Kong, 2012
Emerging Infectious Diseases, 2013 A natural recombinant of coxsackievirus A2 was found in 4 children with respiratory symptoms in Hong Kong, China, during the summer of 2012. Two of these children died. Vigilant monitoring of this emerging recombinant enterovirus is needed to prevent its
Cyril C.Y. Yip +9 more
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Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Within-Host Recombination in the Foot-and-Mouth Disease Virus Genome
Viruses, 2018 Recombination is one of the determinants of genetic diversity in the foot-and-mouth disease virus (FMDV). FMDV sequences have a mosaic structure caused by extensive intra- and inter-serotype recombination, with the exception of the capsid-encoding region.
Luca Ferretti +9 more
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Alternative lengthening of telomeres: remodeling the telomere architecture
Frontiers in Oncology, 2013 To escape from the normal limits on proliferative potential, cancer cells must employ a means to counteract the gradual telomere attrition that accompanies semi-conservative DNA replication.
Dimitri eConomos +2 more
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