Results 51 to 60 of about 530,778 (295)

Mitotic recombination between homologous chromosomes drives genomic diversity in diatoms [PDF]

, 2021
Petra Bulánková, Mirna Sekulić, Denis Jallet, Charlotte Nef, Cock van Oosterhout, Tom O. Delmont, Ilse Vercauteren, Cristina Maria Osuna‐Cruz, Emmelien Vancaester, Thomas Möck, Koen Sabbe, Fayza Daboussi, Chris Bowler, Wim Vyverman, Klaas Vandepoele, Lieven De Veylder   +15 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Description of the Seminiferous Epithelium Cycle Stages in the Zebra Finch Taeniopygia guttata

Animals
Spermatogenesis in passerine birds remains poorly characterized. Previous studies focused on the steps of spermiogenesis, while a detailed staging of the seminiferous epithelium cycle is still lacking for this order.
Tatiana Bikchurina, Daria Rubtsova, Daria Odnoprienko, Pavel Borodin, Anna Torgasheva, Lyubov Malinovskaya   +5 more
doaj   +1 more source

Genomic Comparisons Reveal Microevolutionary Differences in Mycobacterium abscessus Subspecies

Frontiers in Microbiology, 2017
Mycobacterium abscessus, a rapid-growing non-tuberculous mycobacterium, has been the cause of sporadic and outbreak infections world-wide. The subspecies in M. abscessus complex (M. abscessus, M. massiliense, and M.
Joon L. Tan, Kee P. Ng, Chia S. Ong, Yun F. Ngeow   +3 more
doaj   +1 more source

Single-crossover recombination and ancestral recombination trees [PDF]

Journal of Mathematical Biology, 2013
J. Math. Biol., in press.
Baake, Ellen, von Wangenheim, Ute
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Genetic confirmation of mungbean (Vigna radiata) and mashbean (Vigna mungo) interspecific recombinants using molecular markers

Frontiers in Plant Science, 2015
The present study was conducted with the aim to investigate recombination between mungbean (female) and mashbean (male) interspecific crosses using molecular markers i.e., URP (Universal Rice Primers), RAPD (Random Amplified Polymorphic DNA) and SSR ...
Ghulam eAbbas, Amjad eHameed, Muhammad eRizwan, Muhammad eAhsan, Muhammad Jawad eAsghar, Nayyer eIqbal   +5 more
doaj   +1 more source

Orthohantaviruses, Emerging Zoonotic Pathogens

Pathogens, 2020
Orthohantaviruses give rise to the emerging infections such as of hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) in Eurasia and the Americas, respectively.
Emmanuel Kabwe, Yuriy Davidyuk, Anton Shamsutdinov, Ekaterina Garanina, Ekaterina Martynova, Kristina Kitaeva, Moffat Malisheni, Guzel Isaeva, Tatiana Savitskaya, Richard A. Urbanowicz, Sergey Morzunov, Cyprian Katongo, Albert Rizvanov, Svetlana Khaiboullina   +13 more
doaj   +1 more source

GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1 ‐dependent manner [PDF]

, 2023
Munan Shi, Jiajia Hou, Weichu Liang, Qianwen Li, Shan Shao, Shusheng Ci, Chuanjun Shu, Xingqi Zhao, Shanmeizi Zhao, Miaoling Huang, Congye Wu, Zhigang Hu, Lingfeng He, Zhigang Guo, Feiyan Pan   +14 more
openalex   +1 more source

Recombinant Influenza Vaccines [PDF]

Acta Naturae, 2012
This review covers the problems encountered in the construction and production of new recombinant influenza vaccines. New approaches to the development of influenza vaccines are investigated; they include reverse genetics methods, production of virus-like particles, and DNA- and viral vector-based vaccines.
Sedova, E., Shcherbinin, D., Migunov, A., Smirnov, Iu, Logunov, D., Shmarov, M., Tsybalova, L., Naroditskiĭ, B., Kiselev, O., Gintsburg, A.   +9 more
openaire   +3 more sources