Results 51 to 60 of about 1,036,111 (281)

WGS- versus ORF5-Based Typing of PRRSV: A Belgian Case Study

open access: yesViruses, 2021
Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of one of the most widespread and economically devastating diseases in the swine industry.
Frank Vandenbussche   +4 more
doaj   +1 more source

Delayed Recombination and Cosmic Parameters

open access: yes, 2008
Current cosmological constraints from Cosmic Microwave Background (CMB) anisotropies are typically derived assuming a standard recombination scheme, however additional resonance and ionizing radiation sources can delay recombination, altering the cosmic ...
Alessandro Melchiorri   +7 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

HIV-1 RNA genome packaging: it’s G-rated

open access: yesmBio
A member of the Retroviridae, human immunodeficiency virus type 1 (HIV-1), uses the RNA genome packaged into nascent virions to transfer genetic information to its progeny.
Alice Duchon, Wei-Shau Hu
doaj   +1 more source

Prevention and Control of Porcine Epidemic Diarrhea: The Development of Recombination-Resistant Live Attenuated Vaccines

open access: yesViruses, 2022
Porcine epidemic diarrhea (PED), causing up to 100% mortality in neonatal pigs, is a highly contagious enteric disease caused by PED virus (PEDV). The highly virulent genogroup 2 (G2) PEDV emerged in 2010 and has caused huge economic losses to the pork ...
Xiaoyu Niu, Qiuhong Wang
doaj   +1 more source

Three-body recombination at finite energy within an optical model

open access: yes, 2013
We investigate three-boson recombination of equal mass systems as function of (negative) scattering length, mass, finite energy, and finite temperature. An optical model with an imaginary potential at short distance reproduces experimental recombination ...
Fedorov, D. V.   +3 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Location and Identification on Chromosome 3B of Bread Wheat of Genes Affecting Chiasma Number

open access: yesPlants, 2022
Understanding meiotic crossover (CO) variation in crops like bread wheat (Triticum aestivum L.) is necessary as COs are essential to create new, original and powerful combinations of genes for traits of agronomical interest.
Benoit Darrier   +7 more
doaj   +1 more source

Norovirus recombination

open access: yesJournal of General Virology, 2007
RNA recombination is a significant driving force in viral evolution. Increased awareness of recombination within the genusNorovirusof the familyCalicivirushas led to a rise in the identification of norovirus (NoV) recombinants and they are now reported at high frequency.
Bull, Rowena, Tanaka, Mark, White, Peter
openaire   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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