Results 91 to 100 of about 9,223,247 (288)

Bio‐Inspired Object Retrieval via Proximity‐Guided Adaptive Thigmotactic Exploration and Neuromorphic Recognition

Advanced Robotics Research, EarlyView.
Sparse active‐infrared proximity sensing is coupled to an adaptive thigmotactic controller for camera‐inaccessible object retrieval. After grasping, receptor‐informed encoding transforms force, temperature, and wrist force–torque signals into spike trains for spiking neural network recognition.
Fengyi Wang, Nitish Thakor, Gordon Cheng
wiley   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

Evaluation of a novel anti-oxidant Ubiquinol acetate (EnQ10) for its safety by in vitro methods

Heliyon
Background: As an active form of Coenzyme Q10 (CoQ10), Ubiquinol acetate (EnQ10) is a newly developed, chemically stable, and physiologically active novel antioxidant. In addition to its anti-oxidant properties, CoQ10 is a useful cosmetic agent for human
Mohan Cheluru Umesh, K.M. Geetha, Srinivas Seekallu   +2 more
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

TMEM45A Is Dispensable for Epidermal Morphogenesis, Keratinization and Barrier Formation. [PDF]

PLoS ONE, 2016
TMEM45A gene encodes an initially uncharacterized predicted transmembrane protein. We previously showed that this gene is highly expressed in keratinocytes where its expression correlates with keratinization, suggesting a role in normal epidermal ...
Aurélie Hayez, Edith Roegiers, Jérémy Malaisse, Benoit Balau, Christiane Sterpin, Younes Achouri, Catherine Lambert De Rouvroit, Yves Poumay, Carine Michiels, Olivier De Backer   +9 more
doaj   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source

In Vitro Investigation of Traditional Medicine Recipes Used in Bukavu (DR-Congo) to Treat Trichophyton rubrum Dermatophytosis

Microbiology Research
Twenty natural products used in traditional medicine to treat dermatophytosis were evaluated for their efficacy against Trichophyton rubrum, the most frequent dermatophyte infecting humans.
Alexis Cizungu Murhula, Valérie De Glas, Eléa Denil, Yves Poumay   +3 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Differential impacts of nickel toxicity: NiO and NiSO4 on skin health and barrier function

Ecotoxicology and Environmental Safety
Nickel is recognized as a potent skin sensitizer and a common cause of contact dermatitis. Nickel and its compounds are often associated with particulate matter in industrial settings.
Denisse Esther Mallaupoma Camarena, Mariana Corrêa Giannella, Julia de Toledo Bagatin, Silvia Romano de Assis, Tao Chen, Melanie Jane Bailey, Catia Costa, Ella Schneider, Johanna von Gerichten, Silvia Berlanga de Moraes Barros, Natalie Belsey, Silvya Stuchi Maria-Engler   +11 more
doaj   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source