Results 61 to 70 of about 9,338,850 (366)

Rationale for extent of operation choice in rectal cancer

Journal of Education, Health and Sport, 2021
Introduction. Colorectal cancer (CRC) remains relevant occupying one of the leading places in morbidity and mortality among oncological diseases. It reaches 13.5% in the structure of tumor diseases tending to increase.
R. Nikitenko, V. Kosovan, K. Vorotyntseva, E. Koichev   +3 more
doaj   +1 more source

Covariance Self-Attention Dual Path UNet for Rectal Tumor Segmentation [PDF]

arXiv, 2020
Deep learning algorithms are preferable for rectal tumor segmentation. However, it is still a challenge task to accurately segment and identify the locations and sizes of rectal tumors by using deep learning methods. To increase the capability of extracting enough feature information for rectal tumor segmentation, we propose a Covariance Self-Attention
arxiv  

Attention Augmented ConvNeXt UNet For Rectal Tumour Segmentation [PDF]

arXiv, 2022
It is a challenge to segment the location and size of rectal cancer tumours through deep learning. In this paper, in order to improve the ability of extracting suffi-cient feature information in rectal tumour segmentation, attention enlarged ConvNeXt UNet (AACN-UNet), is proposed.
arxiv  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Rectal suction biopsy versus incisional rectal biopsy in the diagnosis of Hirschsprung disease

Pediatric Surgery International, 2022
Abstract Background Hirschsprung disease is one of the most common congenital anomalies that affects colorectal function. Rectal biopsy demonstrating the absence of ganglion cells in the affected bowel is the gold standard for diagnosis. Suction and incisional rectal biopsies are appropriate methods for obtaining diagnostic tissue. The goal of
Nicole, Green, Caitlin A, Smith, Miranda C, Bradford, Lusine, Ambartsumyan, Raj P, Kapur   +4 more
openaire   +2 more sources

Dosimetric uncertainties related to the elasticity of bladder and rectal walls: Adenocarcinoma of the prostate [PDF]

cancer radioth\'erapie 15, 3 (2011) 168-240, 2011
Purpose. - Radiotherapy is an important treatment for prostate cancer.During treatment sessions, bladder and rectal repletion is difficult to quantify and cannot be measured with a single and initial CT scan acquisition. Some methods, such as image-guided radiation therapy and dose-guided radiation therapy, aimto compensate thismissing information ...
arxiv   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

What is Causing This Man\u27s Rectal Pain and Urinary Retention? [PDF]

, 2016
Case: A 23-year-old man presented to an urgent care office with a 2-week history of rectal pain and scant rectal bleeding. In the few days leading up to his presentation, he also had a fever of 101° F (38.3° C), inguinal lymphadenopathy, and urinary ...
McKenney-Drake, Mikaela L., Roman, Christopher T., Veness, Kali E.   +2 more
core   +2 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis [PDF]

, 2016
TNF-α is involved in the mechanisms that initiate inflammatory bowel diseases (IBDs). Anti-TNF-α drugs, such as infliximab (IFX), cause non-responsiveness and side effects, indicating the need to investigate alternative therapies for these diseases.
Barrios, Bibiana Elisabet, Correa, Silvia Graciela, De Paula Silva, Marina, Maccio Maretto, Lisa, Oliani, Sonia María, Poliselli Farsky, Sandra Helena, Sena, Angela   +6 more
core   +1 more source