Results 61 to 70 of about 9,310,159 (342)

High-resolution rectoscopy using MHz optical coherence tomography: a step towards real time 3D endoscopy

open access: yesScientific Reports
Colonoscopy and endoscopic ultrasound play pivotal roles in the assessment of rectal diseases, especially rectal cancer and inflammatory bowel diseases. Optical coherence tomography (OCT) offers a superior depth resolution, which is a critical factor for
Berenice Schulte   +11 more
doaj   +1 more source

A new technique of laparoscopic surgery for rectal disease.

open access: yesRevista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 2004
Laparoscopic rectal surgery is a technique that has to be done in a narrow space: the pelvis. If an immoderate operation is performed with a difficult view, for example in female where the field is disturbed by uterus, it is possible to produce organ trauma or an unexpected bleeding.
Hanai, T   +7 more
openaire   +4 more sources

MTCH2 Deficiency Promotes E2F4/TFRC‐Mediated Ferroptosis and Sensitizes Colorectal Cancer Liver Metastasis to Sorafenib

open access: yesAdvanced Science, EarlyView.
This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing   +18 more
wiley   +1 more source

Rectal and Naris Swabs: Practical and Informative Samples for Analyzing the Microbiota of Critically Ill Patients

open access: yesmSphere, 2018
Commensal microbiota are immunomodulatory, and their pathological perturbation can affect the risk and outcomes of infectious and inflammatory diseases.
Saumya Bansal   +6 more
doaj   +1 more source

ACSS2‐Mediated Histone H4 Lysine 12 Crotonylation (H4K12cr) Alleviates Colitis via Enhancing Transcription of CLDN7

open access: yesAdvanced Science, EarlyView.
Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan   +14 more
wiley   +1 more source

MRI in local staging of rectal cancer: an update

open access: yesDiagnostic and Interventional Radiology, 2014
Preoperative imaging for staging of rectal cancer has become an important aspect of current approach to rectal cancer management, because it helps to select suitable patients for neoadjuvant chemoradiotherapy and determine the appropriate surgical ...
Ümit Tapan   +2 more
doaj   +1 more source

Conservative treatment of hemorrhoids: focus on combination tribenoside and lidocaine

open access: yesАмбулаторная хирургия, 2019
Hemorrhoidal  disease  has been  known since  ancient  times  and remains  one of the  most  common human  diseases. This review presents the results  of tribenoside and lidocaine combinations used in the conservative therapy of hemorrhoids, which give ...
D. I. Trukhan   +2 more
doaj   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

open access: yesAdvanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian   +9 more
wiley   +1 more source

Surgical Treatment of Rectal Prolapse (History of the Issue and Modern Perspective — Literature Review)

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to assess the data on the most common surgical interventions for rectal prolapse.Key points. At present, there are more than 100 methods of surgical correction of rectal prolapse that are carried out by means of the perineal or abdominal approach ...
O. M. Biryukov   +7 more
doaj   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

open access: yesAdvanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro   +10 more
wiley   +1 more source

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