Results 141 to 150 of about 4,044,683 (313)

Seleção genômica ampla e novos métodos de melhoramento do milho Genome wide selection and new methods of maize breeding

Revista Ceres, 2012
Os objetivos deste trabalho foram verificar a acurácia do método da Seleção Genômica Ampla (GWS) no melhoramento de milho nas condições de estresse nutricional e propor novos métodos de melhoramento baseados em GWS. Foram estimados os dois componentes da
Roberto Fritsche-Neto, Marcos Deon Vilela Resende, Glauco Vieira Miranda, Júlio César DoVale   +3 more
doaj  

Marker-Assisted Recurrent Selection for Pyramiding Leaf Rust and Coffee Berry Disease Resistance Alleles in Coffea arabica L. [PDF]

Genes (Basel), 2023
Saavedra LM, Caixeta ET, Barka GD, Borém A, Zambolim L, Nascimento M, Cruz CD, Oliveira ACB, Pereira AA.   +8 more
europepmc   +1 more source

Molecular breeding of sugarcane using linkage disequilibrium maps and quantitative trait alleles : [Abstract W247] [PDF]

, 2009
Sugarcane breeding generally involves forms of recurrent selection using overlapping generations of parent genotypes, with the number of parents used in the order of 100 to 400, depending on the size of the breeding program.
Butterfield, Mike, D'Hont, Angélique, Keeping, Malcom G., Sewpersad, Nikki   +3 more
core  

Genetic progress after cycles of upland rice recurrent selection

, 2015
Periodic assessment of the genetic progress made in recurrent selection programs is essential for assessing the evolution of the programs and identifying the main factors that have contributed to this progress.
O. P. M. Júnior, P. G. S. Melo, O. P. Morais, A. Castro, F. Breseghello, M. M. Utumi, J. A. Pereira, F. J. Wruck, J. M. C. Filho   +8 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

An uncued brain-computer interface using reservoir computing [PDF]

, 2010
Brain-Computer Interfaces are an important and promising avenue for possible next-generation assistive devices. In this article, we show how Reservoir Comput- ing – a computationally efficient way of training recurrent neural networks – com- bined with a
Buteneers, Pieter, Kindermans, Pieter-Jan, Schrauwen, Benjamin, Verstraeten, David   +3 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Heterosis and Responses to Selection in Orange-Fleshed Sweetpotato (Ipomoea batatas L.) Improved Using Reciprocal Recurrent Selection. [PDF]

Front Plant Sci, 2022
Grüneberg WJ, De Boeck B, Diaz F, Eyzaguirre R, Low JW, Reif JC, Campos H.   +6 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source