Results 1 to 10 of about 1,001,641 (160)

Proton-Coupled Electron Flow in Protein Redox Machines [PDF]

open access: yesChemical Reviews, 2010
Electron transfer (ET) reactions are fundamental steps in biological redox processes. Respiration is a case in point: at least 15 ET reactions are required to take reducing equivalents from NADH, deposit them in O_2, and generate the electrochemical ...
Jillian L Dempsey
exaly   +3 more sources

Keap1-Nrf2 Pathway Regulates ALDH and Contributes to Radioresistance in Breast Cancer Stem Cells

open access: yesCells, 2021
Tumor recurrence after radiotherapy due to the presence of breast cancer stem cells (BCSCs) is a clinical challenge, and the mechanism remains unclear.
Dinisha Kamble   +3 more
doaj   +1 more source

Highly Polymorphic Materials and Dissolution Behaviour: The Peculiar Case of Rifaximin

open access: yesPharmaceutics, 2022
Rifaximin is a locally acting antibiotic practically insoluble in water. It presents several crystal phases characterized by different degrees of hydration. The aim of this work is to investigate the dissolution behaviour of rifaximin α, β, and amorphous
Annalisa Bianchera   +4 more
doaj   +1 more source

A generalized approach for the calculation and automation of potentiometric titrations Part 2. Redox Titrations [PDF]

open access: yes, 1984
The very fast calculation procedure described earlier is applied to calculate the titration curves of complicated redox systems. The theory is extended slightly to cover inhomogeneous redox systems.
Bos, M., Linden, W.E. van der, Stur, J.
core   +11 more sources

miR-140-5p Attenuates Hypoxia-Induced Breast Cancer Progression by Targeting Nrf2/HO-1 Axis in a Keap1-Independent Mechanism

open access: yesCells, 2021
Hypoxia and oxidative stress significantly contribute to breast cancer (BC) progression. Although hypoxia-inducible factor 1α (Hif-1α) is considered a key effector of the cellular response to hypoxia, nuclear factor erythroid 2–related factor 2 (Nrf2), a
Megharani Mahajan, Sandhya Sitasawad
doaj   +1 more source

Understanding Cysteine Chemistry Using Conventional and Serial X-ray Protein Crystallography

open access: yesCrystals, 2022
Proteins that use cysteine residues for catalysis or regulation are widely distributed and intensively studied, with many biomedically important examples.
Nathan Smith, Mark A. Wilson
doaj   +1 more source

The C-terminal region of the oxidoreductase MIA40 stabilizes its cytosolic precursor during mitochondrial import

open access: yesBMC Biology, 2020
Background The mitochondrial intermembrane space (IMS) is home to proteins fulfilling numerous essential cellular processes, particularly in metabolism and mitochondrial function.
Lena Maria Murschall   +7 more
doaj   +1 more source

Cross-linking between cysteine and lysine, tryptophan or tyrosine in peptides and proteins treated with hypochlorous acid and other reactive halogens

open access: yesRedox Biochemistry and Chemistry, 2023
Cysteine residues are the most favored targets for oxidation by hypochlorous acid and other reactive halogen species. The end-products of cysteine oxidation are usually considered to be reversibly formed disulfides and the more highly oxidized sulfinic ...
Nicholas J. Magon   +3 more
doaj   +1 more source

The thermodynamic landscape of carbon redox biochemistry [PDF]

open access: yes, 2018
Redox biochemistry plays a key role in the transduction of chemical energy in all living systems. Observed redox reactions in metabolic networks represent only a minuscule fraction of the space of all possible redox reactions.
Aspuru-Guzik, Alán   +7 more
core   +1 more source

EGCG-derived polymeric oxidation products enhance insulin sensitivity in db/db mice

open access: yesRedox Biology, 2022
The present study investigated the influence of epigallocatechin-3-gallate (EGCG) and its autoxidation products on insulin sensitivity in db/db mice.
Ximing Wu   +6 more
doaj   +1 more source

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