Results 101 to 110 of about 1,001,790 (306)

Development of bioluminescent reporter Trypanosoma cruzi and bioassay for compound screening

Frontiers in Chemical Biology
Trypanosoma cruzi is the etiologic agent of Chagas’ disease, a debilitating and mortal zoonotic illness that threatens the lives of several millions of people in the American continent. The acute phase is underdiagnosed and there is no curative treatment
Cristina Quiroga, Marcelo Incerti, Diego Benitez, Eduardo Manta, Andrea Medeiros, Andrea Medeiros, Marcelo A. Comini   +6 more
doaj   +1 more source

Leaf Eh and pH: A Novel Indicator of Plant Stress. Spatial, Temporal and Genotypic Variability in Rice (Oryza sativa L.) [PDF]

, 2019
A wealth of knowledge has been published in the last decade on redox regulations in plants. However, these works remained largely at cellular and organelle levels. Simple indicators of oxidative stress at the plant level are still missing. We developed a
Audebert, A., Benada. J., Boulakia, S., Bousset, L., Dieng, I., Futakuchi, K., Husson, O., Joseph, S., Menozzi, P., Sarthou, J-P., Soglonou, B., Tano, F.   +11 more
core   +1 more source

Brain Redox Imaging

, 2010
Nitroxyl contrast agents (nitroxyl radicals, also known as nitroxide) are paramagnetic species, which can react with reactive oxygen species (ROS) to lose paramagnetism to be diamagnetic species. The paramagnetic nitroxyl radical forms can be detected by using electron paramagnetic resonance imaging (EPRI), Overhauser MRI (OMRI), or MRI.
Ken-ichiro, Matsumoto, Fuminori, Hyodo, Kazunori, Anzai, Hideo, Utsumi, James B, Mitchell, Murali C, Krishna   +5 more
openaire   +3 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Tetrahydrobiopterin as a rheostat of cell resistance to oxidant injury

Redox Biology
Tetrahydrobiopterin (BH4) deficiency is caused by genetic abnormalities that impair its biosynthesis and recycling, which trigger neurochemical, metabolic, and redox imbalances.
R. Steven Traeger, James Woodcock, Sidhartha Tan, Zhongjie Shi, Jeannette Vasquez-Vivar   +4 more
doaj   +1 more source

Strong Correlations in Actinide Redox Reactions

, 2011
Reduction-oxidation (redox) reactions of the redox couples An(VI)/An(V), An(V)/An(IV), and An(IV)/An(III), where An is an element in the family of early actinides (U, Np, and Pu), as well as Am(VI)/Am(V) and Am(V)/Am(III), are modeled by combining ...
Choppin G. R., Clark D. L., J. B. Marston, Roberto J., S. E. Horowitz   +4 more
core   +1 more source

Triggering redox activity in a thiophene compound: radical stabilization and coordination chemistry [PDF]

, 2006
The synthesis, metalation, and redox properties of an acyclic bis(iminothienyl)methene L− are presented. This π-conjugated anion displays pronounced redox activity, undergoing facile one-electron oxidation to the acyclic, metal-free, neutral radical L ...
Davison, Gray, Gray, Schrauzer, Eisenberg, Sproules, Lyons, Kaim, Krężel, Jacquet, Huang, Broere, Greenhalgh, Luca, Munhá, Lyaskovskyy, Praneeth, Kaim, Chirik, Chirik, Annibale, Pankhurst, Pankhurst, Kochem, Reddy, Schweyen, Yoshida, Tanaka, Claessens, Hennessy, Loudet, Kaszyński, Chatterjee, Rasmussen, Gopalakrishna, Wakamiya, Tabakovic, d'Oro, Singh, Kawase, Davenport, Kia, Chen, Doshi, Latos-Grazynski, Lucas, Lane   +46 more
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Redox modulation of plant developmental regulators from the class I TCP transcription factor family [PDF]

, 2013
TEOSINTE BRANCHED1-CYCLOIDEA-PROLIFERATING CELL FACTOR1 (TCP) transcription factors participate in plant developmental processes associated with cell proliferation and growth.
Gonzalez, Daniel Hector, Güttlein, Leandro, Viola, Ivana Lorena   +2 more
core   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source