Results 81 to 90 of about 1,075,897 (355)
Mitochondrial redox adaptations enable alternative aspartate synthesis in SDH-deficient cells
eLife, 2023 The oxidative tricarboxylic acid (TCA) cycle is a central mitochondrial pathway integrating catabolic conversions of NAD +to NADH and anabolic production of aspartate, a key amino acid for cell proliferation.
Madeleine L Hart +8 more
doaj +1 more source
Redox regulation of macrophages
Redox BiologyRedox signaling, a mode of signal transduction that involves the transfer of electrons from a nucleophilic to electrophilic molecule, has emerged as an essential regulator of inflammatory macrophages.
Nhien V. Tran, E. Mills
semanticscholar +1 more source
Redox classification and calibration of redox thresholds in sedimentary systems
, 2020 Existing redox classifications and the calibrations of elemental proxies to modern environmental redox scales are in need of re-evaluation. Here, we review environmental redox classifications, commonly used elemental redox proxies, and their ...
T. Algeo, Chao Li
semanticscholar +1 more source
Glutathione and peroxisome redox homeostasis
Redox Biology, 2023 Despite intensive research on peroxisome biochemistry, the role of glutathione in peroxisomal redox homeostasis has remained a matter of speculation for many years, and only recently has this issue started to be experimentally addressed.
M. J. Ferreira +6 more
semanticscholar +1 more source
The redox biology of redox-inert zinc ions [PDF]
Free Radical Biology and Medicine, 2019 Zinc(II) ions are redox-inert in biology. Yet, their interaction with sulfur of cysteine in cellular proteins can confer ligand-centered redox activity on zinc coordination sites, control protein functions, and generate signalling zinc ions as potent effectors of many cellular processes.
openaire +3 more sources
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Redox outside the Box: Linking Extracellular Redox Remodeling with Intracellular Redox Metabolism [PDF]
Journal of Biological Chemistry, 2012 Aerobic organisms generate reactive oxygen species as metabolic side products and must achieve a delicate balance between using them for signaling cellular functions and protecting against collateral damage. Small molecule (e.g. glutathione and cysteine)- and protein (e.g.
openaire +2 more sources
Redox-Triggered Disassembly of Nanosized Liposomes Containing Ferrocene-Appended Amphiphiles
, 2019 We report a redox-responsive liposomal system capable of oxidatively triggered disassembly. We describe the synthesis, electrochemical characterization, and incorporation into vesicles of an alternative redox lipid with significantly improved synthetic ...
Rustam Z. Khaliullin +7 more
core +1 more source
Electronic Conductance Resonance in Non-Redox-Active Proteins
, 2020 Bioelectronics research has mainly focused on redox-active proteins because of their role in biological charge transport. In these proteins, electronic conductance is a maximum when electrons are injected at the known redox potential of the protein.
Weisi Song +9 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source