Results 81 to 90 of about 706,705 (366)
Environmental toxicity, redox signaling and lung inflammation:the role of glutathione [PDF]
, 2009 Glutathione (gamma-glutamyl-cysteinyl-glycine, GSH) is the most abundant intracellular antioxidant thiol and is central to redox defense during oxidative stress.
Saibal K. Biswas +3 more
core +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Modelling and simulation of all-vanadium redox flow batteries [PDF]
, 2011 Properties and applications of all-vanadium redox flow batteries are discussed and a two-dimensional model is developed. The model, which is based on a comprehensive description of mass, charge, energy and momentum transport and conservation, is combined
Al-Fetlawi, Hassan Abdul-Zehra Abdul-Yima
core
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
npj MicrogravitySkeletal muscles overcome terrestrial, gravitational loading by producing tensile forces that produce movement through joint rotation. Conversely, the microgravity of spaceflight reduces tensile loads in working skeletal muscles, causing an adaptive ...
Khaled Y. Kamal +3 more
doaj +1 more source
Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice
BMC Genomics, 2017 Background Nuclear Factor Erythroid-derived 2-like 2 (Nrf2) senses oxidative environments and/or stress and initiates a cytoprotective response through transcriptional activation of antioxidant and detoxification genes.
Justin M. Quiles +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Investigation of the contribution of redox stress to the therapy resistance of cells experiencing hypoxia [PDF]
There is a well-established relationship between hypoxia (low oxygen) and poor patient prognosis. Hypoxia has been described as a major mechanism of resistance to all standard therapies.
Twigger, Sophie Alice
core +2 more sources
Redox-sensitive materials for drug delivery : targeting the correct intracellular environment, tuning release rates, and appropriate predictive systems [PDF]
, 2014 Significance: The development of responsive drug delivery systems (DDS) holds great promise as a tool for improving the pharmacokinetic properties of drug compounds.
Gibson, Matthew I.; id_orcid +4 more
core +1 more source