Results 71 to 80 of about 706,705 (366)

PAMM: A Redox Regulatory Protein That Modulates Osteoclast Differentiation [PDF]

, 2010
The central role of reactive oxygen species (ROS) in osteoclast differentiation and in bone homeostasis prompted us to characterize the redox regulatory system of osteoclasts.
SASAKI, Hajime, ODGREN, Paul R., BATTAGLINO, Ricardo A., MORSE, Leslie R., SILVA, Raquel Assed Bezerra da, XU, Yan, STASHENKO, Philip   +6 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Mitochondrial redox adaptations enable alternative aspartate synthesis in SDH-deficient cells

eLife, 2023
The oxidative tricarboxylic acid (TCA) cycle is a central mitochondrial pathway integrating catabolic conversions of NAD +to NADH and anabolic production of aspartate, a key amino acid for cell proliferation.
Madeleine L Hart, Evan Quon, Anna-Lena BG Vigil, Ian A Engstrom, Oliver J Newsom, Kristian Davidsen, Pia Hoellerbauer, Samantha M Carlisle, Lucas B Sullivan   +8 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Water deprivation-induced hypoxia and oxidative stress physiology responses in respiratory organs of the Indian stinging fish in near coastal zones [PDF]

PeerJ
Background Water deprivation-induced hypoxia stress (WDIHS) has been extensively investigated in numerous fish species due to their adaptation with accessory respiratory organs to respire air but this has not been studied in Indian stinging fish ...
Samar Gourav Pati, Falguni Panda, Abhipsa Bal, Biswaranjan Paital, Dipak Kumar Sahoo   +4 more
doaj   +2 more sources

A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex

Nature Communications, 2020
Peroxiredoxin 2 (Prx2) was previously shown to transfer H2O2-derived oxidative equivalents to STAT3, generating disulfide-linked dimers and tetramers. Here the authors show that the interaction between Prx2 and STAT3 at the plasma membrane is mediated by
Deepti Talwar, Joris Messens, Tobias P. Dick   +2 more
doaj   +1 more source

Redox Pairs in Redox Flow Batteries

Journal of the Korean Electrochemical Society, 2013
레독스 플로우 전지(RFB)는 대형에너지 장치로서 신재생 에너지와 같은 전력발생이 일정하지 못한 상황이나 전력수요가 급증감하여 효율적인 에너지의 운용이 요구될 때 효과적으로 사용할 수있는 전지모델이다. 일부 상용화된 종류도 있지만 다양한 레독스 쌍과 소재가 연구됨에 따라 개선의 여지가 많은 전지이다. 본 총설에서는 전지의 레독스 쌍(redox pair)의 종류들에 대한 설명을 통하여 레독스 플로우 전지의 전반적인 이해를 돕고자 한다. 레독스 쌍의 혼합오염, cross-over, 이온 선택성, 용해도 등의 개선을 통해서 새로운 레독스 플로우 전지의 탄생을 기대할 수있다.
Byunghyun Hwang, Ketack Kim
openaire   +2 more sources

Redox-Switchable Binding Properties of the ATP–Aptamer [PDF]

, 2019
In this study, we report on a redox-controllable and reversible complete “ON”/“OFF”-switchable aptamer binding to ATP. A series of methylene blue-modified ATP–aptamers was synthesized, revealing improved binding affinities toward ATP as compared to the ...
Guo-Feng Luo (1488661), Michael Fadeev, Yonatan Biniuri (1438345), Verena Wulf (1919818), Guo-Feng Luo, Yonatan Biniuri, Michael Fadeev (3371720), Verena Wulf, Itamar Willner, Itamar Willner (1273365)   +9 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Organophotocatalytic Radical–Polar Cross-Coupling of Styrylboronic Acids and Redox-Active Esters [PDF]

, 2023
Allan J. B. Watson, Jeremy Brals, Nicholas D’Arcy-Evans, Thomas M. McGuire   +3 more
openalex   +1 more source