Results 71 to 80 of about 677,026 (312)

Water deprivation-induced hypoxia and oxidative stress physiology responses in respiratory organs of the Indian stinging fish in near coastal zones [PDF]

open access: yesPeerJ
Background Water deprivation-induced hypoxia stress (WDIHS) has been extensively investigated in numerous fish species due to their adaptation with accessory respiratory organs to respire air but this has not been studied in Indian stinging fish ...
Samar Gourav Pati   +4 more
doaj   +2 more sources

A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex

open access: yesNature Communications, 2020
Peroxiredoxin 2 (Prx2) was previously shown to transfer H2O2-derived oxidative equivalents to STAT3, generating disulfide-linked dimers and tetramers. Here the authors show that the interaction between Prx2 and STAT3 at the plasma membrane is mediated by
Deepti Talwar   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Redox-Mediated ORR and OER Reactions: Redox Flow Lithium Oxygen Batteries Enabled with a Pair of Soluble Redox Catalysts

open access: yes, 2016
We demonstrate a redox flow lithium oxygen battery (RFLOB) using a pair of soluble redox catalysts, 2,5-di-tert-butyl-p-benzoquinone (DTBBQ) and tris­{4-[2-(2-methoxyethoxy)­ethoxy]­phenyl}­amine (TMPPA).
Qing Wang (27728)   +4 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Omeprazole impairs vascular redox biology and causes xanthine oxidoreductase-mediated endothelial dysfunction

open access: yes, 2021
Proton pump inhibitors (PPIs) are widely used drugs that may increase the cardiovascular risk by mechanisms not entirely known. While PPIs increase asymmetric dimethylarginine (ADMA) levels and inhibit nitric oxide production, it is unknown whether ...
de Angelis, Celio D.   +5 more
core   +1 more source

Rod photoreceptor-specific deletion of cytosolic aspartate aminotransferase, GOT1, causes retinal degeneration

open access: yesFrontiers in Ophthalmology, 2023
Photoreceptor cell death is the cause of vision loss in many forms of retinal disease. Metabolic dysfunction within the outer retina has been shown to be an underlying factor contributing to photoreceptor loss. Therefore, a comprehensive understanding of
Shubha Subramanya   +13 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Cellular Redox Compartments [PDF]

open access: yesAntioxidants & Redox Signaling, 2018
Although initially considered as harmful, reactive oxygen species (ROS) are now also recognized as important signaling molecules affecting various cellular processes. For example, they contribute to the response to hormones, growth factors, or hypoxia, and defense reactions against mechanical or chemical stress. Therefore, different ROS-generating, ROS-
openaire   +3 more sources

Metabolic Control of Redox and Redox Control of Metabolism in Plants [PDF]

open access: yesAntioxidants & Redox Signaling, 2014
Significance: Reduction-oxidation (Redox) status operates as a major integrator of subcellular and extracellular metabolism and is simultaneously itself regulated by metabolic processes. Redox status not only dominates cellular metabolism due to the prominence of NAD(H)
Geigenberger, P., Fernie, A.
openaire   +3 more sources

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