Results 61 to 70 of about 1,075,897 (355)

Overexpression of 2-mercaptoethanesulfonate biosynthesis genes comDE protects methane-producing archaea from oxidative stress

open access: yesJournal of Bacteriology
Coenzyme M (2-mercaptoethane sulfonate, CoM) is an essential low-molecular-weight thiol in methanogenic archaea (methanogens) that serves as a methyl carrier and as a component of CoM-S-S-CoB heterodisulfide comprising CoM and coenzyme B (7 ...
Alicia M. Salvi   +2 more
doaj   +1 more source

2,2′-[(1E,1′E)-1,2-Phenylenebis(azanylylidene)bis(methanylylidene)]bis(4-bromophenol)

open access: yesIUCrData, 2017
In the title compound, C20H14Br2N2O2, there are two intramolecular O—H...N hydrogen bonds forming S(6) ring motifs. The outer benzene rings are inclined to the central benzene ring by 39.09 (11) and 24.31 (11)°, and to one another by 37.12 (11)°.
Souad Dekar, Sabrina Bendia, Kamel Ouari
doaj   +1 more source

Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli

open access: yesNature Communications, 2022
New cryo-EM structures of the formate hydrogenlyase complex from the model bacterium E. coli clarify how electrons and protons move through the complex and are combined to make H2 gas.
Ralf Steinhilper   +3 more
doaj   +1 more source

Measuring Intracellular H2O2 in Intact Human Cells Using the Genetically Encoded Fluorescent Sensor HyPer7

open access: yesBio-Protocol, 2022
Depending on its local concentration, hydrogen peroxide (H2O2) can serve as a cellular signaling molecule but can also cause damage to biomolecules.
Lianne Jacobs   +2 more
doaj   +1 more source

Redox-manipulating nanocarriers for anticancer drug delivery: a systematic review

open access: yesJournal of Nanobiotechnology
Spatiotemporally controlled cargo release is a key advantage of nanocarriers in anti-tumor therapy. Various external or internal stimuli-responsive nanomedicines have been reported for their ability to increase drug levels at the diseased site and ...
Xuan Meng   +5 more
semanticscholar   +1 more source

Charge Transfer Chromophores Derived from 3d-Row Transition Metal Complexes

open access: yesMolecules, 2022
A series of new charge transfer (CT) chromophores of “α-diimine-MII-catecholate” type (where M is 3d-row transition metals—Cu, Ni, Co) were derived from 4,4′-di-tert-butyl-2,2′-bipyridyl and 3,6-di-tert-butyl-o-benzoquinone (3,6-DTBQ) in accordance with ...
Kira I. Pashanova   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Expanding the applications of a bioluminescent mouse infection model of acute African trypanosomiasis

open access: yesFrontiers in Chemical Biology
IntroductionIn vivo imaging technology based on bioluminescence has contributed to the study of different pathophysiological conditions involving inherited or transmissible diseases.
Diego Benítez   +4 more
doaj   +1 more source

Cell Culture Characterization of Prooxidative Chain-Transfer Agents as Novel Cytostatic Drugs

open access: yesMolecules, 2021
Prooxidative therapy is a well-established concept in infectiology and parasitology, in which prooxidative drugs like artemisinin and metronidazole play a pivotal clinical role.
Victoria Heymans   +3 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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