Results 31 to 40 of about 468,423 (315)

Electrochemical Redox Refrigeration [PDF]

open access: yesScientific Reports, 2019
AbstractThe high conformational entropy change of the Fe(CN)63−/4− redox reaction can be used as the basis for a compact electrochemical refrigerator. This device is comparable to a liquid version of a Peltier cooler, with two distinct advantages: (1) the entropy change per carrier (1.5 mV/K) of the electrochemical refrigerant is more than 5 times ...
Ian S. McKay   +2 more
openaire   +2 more sources

Redoxing PTPN22 activity

open access: yeseLife, 2022
The oxidative state of a critical cysteine residue determines the enzymatic activity of a phosphatase involved in T-cell immune responses.
Magdalena Shumanska, Ivan Bogeski
openaire   +4 more sources

Overexpression of 2-mercaptoethanesulfonate biosynthesis genes comDE protects methane-producing archaea from oxidative stress

open access: yesJournal of Bacteriology
Coenzyme M (2-mercaptoethane sulfonate, CoM) is an essential low-molecular-weight thiol in methanogenic archaea (methanogens) that serves as a methyl carrier and as a component of CoM-S-S-CoB heterodisulfide comprising CoM and coenzyme B (7 ...
Alicia M. Salvi   +2 more
doaj   +1 more source

Expanding the applications of a bioluminescent mouse infection model of acute African trypanosomiasis

open access: yesFrontiers in Chemical Biology
IntroductionIn vivo imaging technology based on bioluminescence has contributed to the study of different pathophysiological conditions involving inherited or transmissible diseases.
Diego Benítez   +4 more
doaj   +1 more source

Murine colon organoids as a novel model to study Trypanosoma cruzi infection and interactions with the intestinal epithelium

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Chagas disease (CD) is a life-threatening illness caused by the parasite Trypanosoma cruzi (T. cruzi). With around seven million people infected worldwide and over 50,000 deaths per year, CD is a major public health issue in Latin America. The main route
Hellen Daghero   +6 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Redox outside the Box: Linking Extracellular Redox Remodeling with Intracellular Redox Metabolism [PDF]

open access: yesJournal of Biological Chemistry, 2012
Aerobic organisms generate reactive oxygen species as metabolic side products and must achieve a delicate balance between using them for signaling cellular functions and protecting against collateral damage. Small molecule (e.g. glutathione and cysteine)- and protein (e.g.
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Using the heme peroxidase APEX2 to probe intracellular H2O2 flux and diffusion

open access: yesNature Communications
Currently available genetically encoded H2O2 probes report on the thiol redox state of the probe, which means that they reflect the balance between probe thiol oxidation and reduction.
Mohammad Eid   +4 more
doaj   +1 more source

Arsenic Toxicity on Metabolism and Autophagy in Adipose and Muscle Tissues

open access: yesAntioxidants, 2022
Arsenic, a naturally occurring metalloid derived from the environment, has been studied worldwide for its causative effects in various cancers. However, the effects of arsenic toxicity on the development and progression of metabolic syndrome, including ...
Seung-Hyun Ro   +8 more
doaj   +1 more source

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