Results 11 to 20 of about 211,652 (303)
Regulation of dual oxidase hydrogen peroxide synthesis results in an epithelial respiratory burst
Redox status is a central determinant of cellular activities and redox imbalance is correlated with numerous diseases. NADPH oxidase activity results in formation of H2O2, that, in turn, sets cellular redox status, a key regulator of cellular homeostasis
Gregory E. Conner
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Methane formation driven by light and heat prior to the origin of life and beyond
Methane is a potent greenhouse gas, which likely enabled the evolution of life by keeping the early Earth warm. Here, we demonstrate routes towards abiotic methane and ethane formation under early-earth conditions from methylated sulfur and nitrogen ...
Leonard Ernst +6 more
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The semi-sessile, ectothermic, amphibious mollusc Pila globosa receives less attention for studying its environmental aspects. Its ecological role, ecotoxic and physiological responses to environmental factors including pollution and during dormant ...
Falguni Panda +7 more
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Objectives: Science is the erudite methodical systematic practises to study the structure and behaviour of natural objects and/or phenomena. It clearly unknot about the fact that science is a human (society) need based process that starts with social ...
Kabita Das, Biswaranjan Paital
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Redox-Regulated Chaperones [PDF]
Redox regulation of stress proteins, such as molecular chaperones, guarantees an immediate response to oxidative stress conditions. This review focuses on the two major classes of redox-regulated chaperones, Hsp33 in bacteria and typical 2-Cys peroxiredoxins in eukaryotes.
Caroline, Kumsta, Ursula, Jakob
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Mitochondrial Redox Regulations and Redox Biology of Mitochondria [PDF]
Mitochondria undoubtedly represent a metabolic hub, but also act as a redox hub, controlling cell fate and emanating superoxide/H2O2, which in a regulated form and timing provide redox signaling [...]
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LC3-associated phagocytosis (LAP) is a non-canonical use of the autophagy machinery that can contribute to immune responses. Here, the authors describe the mechanism by which ROS production regulates LAPosome stabilization sustaining MHC II dependent ...
Laure-Anne Ligeon +6 more
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A role for peroxiredoxins in H2O2- and MEKK-dependent activation of the p38 signaling pathway
The p38 mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in the cellular response to various stresses and its deregulation accompanies pathological conditions such as cancer and chronic inflammation.
Ana G. Barata, Tobias P. Dick
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Zika virus (ZIKV) has emerged as a global health issue, yet neither antiviral therapy nor a vaccine are available. ZIKV is an enveloped RNA virus, replicating in the cytoplasm in close association with ER membranes.
Solène Denolly +8 more
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A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex
Peroxiredoxin 2 (Prx2) was previously shown to transfer H2O2-derived oxidative equivalents to STAT3, generating disulfide-linked dimers and tetramers. Here the authors show that the interaction between Prx2 and STAT3 at the plasma membrane is mediated by
Deepti Talwar +2 more
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