Results 11 to 20 of about 211,652 (303)

Regulation of dual oxidase hydrogen peroxide synthesis results in an epithelial respiratory burst

open access: yesRedox Biology, 2021
Redox status is a central determinant of cellular activities and redox imbalance is correlated with numerous diseases. NADPH oxidase activity results in formation of H2O2, that, in turn, sets cellular redox status, a key regulator of cellular homeostasis
Gregory E. Conner
doaj   +2 more sources

Methane formation driven by light and heat prior to the origin of life and beyond

open access: yesNature Communications, 2023
Methane is a potent greenhouse gas, which likely enabled the evolution of life by keeping the early Earth warm. Here, we demonstrate routes towards abiotic methane and ethane formation under early-earth conditions from methylated sulfur and nitrogen ...
Leonard Ernst   +6 more
doaj   +1 more source

Biochemical and molecular responses of the freshwater snail Pila sp. to environmental pollutants, abiotic, and biotic stressors

open access: yesFrontiers in Environmental Science, 2022
The semi-sessile, ectothermic, amphibious mollusc Pila globosa receives less attention for studying its environmental aspects. Its ecological role, ecotoxic and physiological responses to environmental factors including pollution and during dormant ...
Falguni Panda   +7 more
doaj   +1 more source

Future call for policy making to speed up interdisciplinarity between natural and social sciences and humanities in countries such as India

open access: yesHeliyon, 2021
Objectives: Science is the erudite methodical systematic practises to study the structure and behaviour of natural objects and/or phenomena. It clearly unknot about the fact that science is a human (society) need based process that starts with social ...
Kabita Das, Biswaranjan Paital
doaj   +1 more source

Redox-Regulated Chaperones [PDF]

open access: yesBiochemistry, 2009
Redox regulation of stress proteins, such as molecular chaperones, guarantees an immediate response to oxidative stress conditions. This review focuses on the two major classes of redox-regulated chaperones, Hsp33 in bacteria and typical 2-Cys peroxiredoxins in eukaryotes.
Caroline, Kumsta, Ursula, Jakob
openaire   +2 more sources

Mitochondrial Redox Regulations and Redox Biology of Mitochondria [PDF]

open access: yesAntioxidants, 2021
Mitochondria undoubtedly represent a metabolic hub, but also act as a redox hub, controlling cell fate and emanating superoxide/H2O2, which in a regulated form and timing provide redox signaling [...]
openaire   +3 more sources

Oxidation inhibits autophagy protein deconjugation from phagosomes to sustain MHC class II restricted antigen presentation

open access: yesNature Communications, 2021
LC3-associated phagocytosis (LAP) is a non-canonical use of the autophagy machinery that can contribute to immune responses. Here, the authors describe the mechanism by which ROS production regulates LAPosome stabilization sustaining MHC II dependent ...
Laure-Anne Ligeon   +6 more
doaj   +1 more source

A role for peroxiredoxins in H2O2- and MEKK-dependent activation of the p38 signaling pathway

open access: yesRedox Biology, 2020
The p38 mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in the cellular response to various stresses and its deregulation accompanies pathological conditions such as cancer and chronic inflammation.
Ana G. Barata, Tobias P. Dick
doaj   +1 more source

Zika virus remodelled ER membranes contain proviral factors involved in redox and methylation pathways

open access: yesNature Communications, 2023
Zika virus (ZIKV) has emerged as a global health issue, yet neither antiviral therapy nor a vaccine are available. ZIKV is an enveloped RNA virus, replicating in the cytoplasm in close association with ER membranes.
Solène Denolly   +8 more
doaj   +1 more source

A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex

open access: yesNature Communications, 2020
Peroxiredoxin 2 (Prx2) was previously shown to transfer H2O2-derived oxidative equivalents to STAT3, generating disulfide-linked dimers and tetramers. Here the authors show that the interaction between Prx2 and STAT3 at the plasma membrane is mediated by
Deepti Talwar   +2 more
doaj   +1 more source

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