Results 11 to 20 of about 197,483 (259)
Redox regulation of proteasome function
Redox Biology, 2017 Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) were initially regarded mainly as metabolic by-products with damaging properties. Over the last decade, our understanding of their role in metabolism was drastically changed and they were ...
Maria Lefaki +2 more
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Redox Regulation of Cdc25C [PDF]
Journal of Biological Chemistry, 2002 The Cdc25 family of dual specific phosphatases are critical components of cell cycle progression and checkpoint control. Certain stresses such as ultraviolet light stimulate the rapid and selective destruction of Cdc25A protein through a Chk1 protein kinase-dependent pathway.
Pavel A, Savitsky, Toren, Finkel
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Redox regulation of proteostasis. [PDF]
J Biol ChemOxidants produced through endogenous metabolism or encountered in the environment react directly with reactive sites in biological macromolecules. Many proteins, in particular, are susceptible to oxidative damage, which can lead to their altered structure and function.
Duong LD, West JD, Morano KA.
europepmc +3 more sources
Heliyon, 2021 Objectives: Science is the erudite methodical systematic practises to study the structure and behaviour of natural objects and/or phenomena. It clearly unknot about the fact that science is a human (society) need based process that starts with social ...
Kabita Das, Biswaranjan Paital
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Redox-Regulated Chaperones [PDF]
Biochemistry, 2009 Redox regulation of stress proteins, such as molecular chaperones, guarantees an immediate response to oxidative stress conditions. This review focuses on the two major classes of redox-regulated chaperones, Hsp33 in bacteria and typical 2-Cys peroxiredoxins in eukaryotes.
Caroline, Kumsta, Ursula, Jakob
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Mitochondrial Redox Regulations and Redox Biology of Mitochondria [PDF]
Antioxidants, 2021 Mitochondria undoubtedly represent a metabolic hub, but also act as a redox hub, controlling cell fate and emanating superoxide/H2O2, which in a regulated form and timing provide redox signaling [...]
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Nature Communications, 2021 LC3-associated phagocytosis (LAP) is a non-canonical use of the autophagy machinery that can contribute to immune responses. Here, the authors describe the mechanism by which ROS production regulates LAPosome stabilization sustaining MHC II dependent ...
Laure-Anne Ligeon +6 more
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A role for peroxiredoxins in H2O2- and MEKK-dependent activation of the p38 signaling pathway
Redox Biology, 2020 The p38 mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in the cellular response to various stresses and its deregulation accompanies pathological conditions such as cancer and chronic inflammation.
Ana G. Barata, Tobias P. Dick
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Nature Communications, 2023 Zika virus (ZIKV) has emerged as a global health issue, yet neither antiviral therapy nor a vaccine are available. ZIKV is an enveloped RNA virus, replicating in the cytoplasm in close association with ER membranes.
Solène Denolly +8 more
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A role for annexin A2 in scaffolding the peroxiredoxin 2–STAT3 redox relay complex
Nature Communications, 2020 Peroxiredoxin 2 (Prx2) was previously shown to transfer H2O2-derived oxidative equivalents to STAT3, generating disulfide-linked dimers and tetramers. Here the authors show that the interaction between Prx2 and STAT3 at the plasma membrane is mediated by
Deepti Talwar +2 more
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