Results 211 to 220 of about 197,483 (259)
Targeted Redox Regulation α-Ketoglutarate Dehydrogenase Complex for the Treatment of Human Diseases. [PDF]
CellsMailloux RJ.
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Redox regulation of immunometabolism
Nature Reviews Immunology, 2020Metabolic pathways and redox reactions are at the core of life. In the past decade(s), numerous discoveries have shed light on how metabolic pathways determine the cellular fate and function of lymphoid and myeloid cells, giving rise to an area of research referred to as immunometabolism.
Jonathan Muri, Manfred Kopf
openaire +3 more sources
Redox Regulation of the Microcirculation
Comprehensive Physiology, 2020Abstract The microcirculation maintains tissue homeostasis through local regulation of blood flow and oxygen delivery. Perturbations in microvascular function are characteristic of several diseases and may be early indicators of pathological changes in the cardiovascular system and in parenchymal tissue function ...
Andrew O, Kadlec, David D, Gutterman
openaire +2 more sources
Redox regulation: an introduction
Physiologia Plantarum, 2004The redox‐state is a critical determinate of cell function, and any major imbalances can cause severe damage or death. The cellular redox status therefore needs to be sensed and modulated before such imbalances occur. Various redox‐active components are involved in these processes, including thioredoxins, glutaredoxins and other thiol/disulphide ...
Dietz, Karl-Josef, Scheibe, R
openaire +3 more sources
Biochemistry, 2006
We have previously shown that redox agents including superoxide anion radical and nitrogen dioxide can react with GXXXXGK(S/T)C motif-containing GTPases (i.e., Rac1, Cdc42, and RhoA) to stimulate guanine nucleotide release. We now show that the reaction of RhoA with redox agents leads to different functional consequences from that of Rac1 and Cdc42 due
Jongyun, Heo +3 more
openaire +2 more sources
We have previously shown that redox agents including superoxide anion radical and nitrogen dioxide can react with GXXXXGK(S/T)C motif-containing GTPases (i.e., Rac1, Cdc42, and RhoA) to stimulate guanine nucleotide release. We now show that the reaction of RhoA with redox agents leads to different functional consequences from that of Rac1 and Cdc42 due
Jongyun, Heo +3 more
openaire +2 more sources
Redox‐regulation of DNA repair
BioFactors, 2003Evolution has selected for sophisticated biochemical mechanisms to maintain a reduced environment in all living cells. Not only is this regulation essential for the numerous biological process within the cell to occur, but it is also the protective mechanism which prevents the many endogenous and exogenous biological oxidations in the cell.
Lunec, Joseph +3 more
openaire +3 more sources
Redox regulation of protein kinases
Critical Reviews in Biochemistry and Molecular Biology, 2013Reactive oxygen species (ROS) have been long regarded as by‐products of a cascade of reactions stemming from cellular oxygen metabolism, which, if they accumulate to toxic levels, can have detrimental effects on cellular biomolecules. However, more recently, the recognition of ROS as mediators of cellular communications has led to their classification ...
Kate Carroll
exaly +3 more sources
Discoveries in the redox regulation of KRAS
The International Journal of Biochemistry & Cell Biology, 2021Oncogenic KRAS is one of the most common drivers of human cancer. Despite intense research, no effective therapy to directly inhibit oncogenic KRAS has yet been approved and KRAS mutant tumors remain associated with a poor prognosis. This short review discusses the current knowledge of the redox regulation of RAS and examines the newest findings on ...
Maximilian, Kramer-Drauberg +1 more
openaire +2 more sources
Redox Regulation of p53, Redox Effectors Regulated by p53: A Subtle Balance
Antioxidants & Redox Signaling, 2012Reactive oxygen species (ROS), generated by cells as side products of biological reactions, function as secondary messengers by impacting a host of cellular networks involved in maintaining normal homeostatic growth as well as pathological disease states.
Maillet, A., Pervaiz, Shazib
openaire +3 more sources
Redox Regulation and Noncoding RNAs
Antioxidants & Redox Signaling, 2018RNA is a heterogeneous class of molecules with the minority being protein coding. Noncoding RNAs (ncRNAs) are involved in translation and epigenetic control mechanisms of gene expression. Recent Advances: In recent years, the number of identified ncRNAs has dramatically increased and it is now clear that ncRNAs provide a complex layer of differential ...
Matthias S, Leisegang +2 more
openaire +2 more sources