Results 231 to 240 of about 197,483 (259)
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Redox-Regulated Mechanisms in Asthma
Antioxidants & Redox Signaling, 2008Homeostasis of the reduction–oxidation (redox) state is critical to protection from oxidative stress in the lungs. Therefore, the lungs have high levels of antioxidants, including glutathione, heme oxygenase, and superoxide dismutase.
Tomoaki, Hoshino +5 more
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Redox Regulation of Chloroplast Transcription
Antioxidants & Redox Signaling, 2003Chloroplasts are the important plant cell organelles where photosynthesis takes place. Throughout this process, reaction center proteins are degraded and subsequently replenished by redox-responsive gene expression. In addition to well defined posttranscriptional mechanisms at the RNA and protein level, the transcription of chloroplast DNA into RNA ...
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Redox regulation of phosphatase function
Biochemical Society Transactions, 2004Although reactive oxygen species play important roles in cellular physiology as signalling molecules, their molecular targets are largely unknown. A probable group of targets for mediating many of the effects of reactive oxygen species on cell signalling is the large diverse family of cysteine-dependent phosphatases, which includes the protein tyrosine
N R, Leslie +3 more
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Redox regulation of microRNAs in cancer
Cancer Letters, 2018Dysregulation of microRNAs (miRNAs) has long been implicated in tumorigenesis, whereas the underlying mechanisms remain largely unknown. Oxidative stress is a hallmark of cancer that involved in multiple pathophysiological processes, including the aberrant regulation of miRNAs.
Jiang, Lan +4 more
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Redox Regulation of Copper–Metallothionein
Archives of Biochemistry and Biophysics, 1999Copper (Cu) is an essential element whose localization within cells must be carefully controlled to avoid Cu-dependent redox cycling. Metallothioneins (MTs) are cysteine-rich metal-binding proteins that exert cytoprotective effects during metal exposure and oxidative stress.
J P, Fabisiak +7 more
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Redox Regulation of the Cdc25 Phosphatases
Antioxidants & Redox Signaling, 2005The Cdc25 phosphatases are essential for cell-cycle control in eukaryotes under normal conditions and in response to DNA damage via checkpoint controls. Recent evidence indicates direct control of the Cdc25s, and therefore the cell cycle, in response to changes in cellular redox status.
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Redox Regulation in Oxigenic Photosynthesis
2002Photosynthetic cells use the energy from absorbed light to synthesize partially or fully reduced organic compounds such as carbohydrates, fatty acids and amino acids from oxidized substrates. A series of elaborate redox reactions links the fundamental events of light absorption to the ultimate supply of reduced assimilates within the cell and also for ...
Link, G. +3 more
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Redox Regulation of the Coagulation Cascade
Antioxidants & Redox Signaling, 2005Enhanced coagulation and thrombosis are linked to a variety of cardiovascular and metabolic diseases, as well as to cancer. Many of these diseases are also associated with enhanced levels of reactive oxygen species (ROS). Indeed, ROS have been made responsible for promoting many of these diseases. They have been shown not only to be cytotoxic, but also
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Redox regulation of Ran GTPase
Biochemical and Biophysical Research Communications, 2008Ran, a small Ras-like GTP-binding nuclear protein, plays a key role in modulation of various cellular signaling events including the cell cycle. This study shows that a cellular redox agent (nitrogen dioxide) facilitates Ran guanine nucleotide dissociation, and identifies a unique Ran redox architecture involved in that process.
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