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Redox regulation of chlorophyll biosynthesis
Phytochemistry, 2010Chlorophyll captures and redirects light-energy and is thus essential for photosynthetic organisms. The demand for chlorophyll differs throughout the day and night and in response to changing light conditions. Moreover, the chlorophyll biosynthesis pathway is up to certain points shared between the different tetrapyrroles; chlorophyll, heme, siroheme ...
Stenbæk, Anne, Jensen, Poul Erik
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Progress in Retinal and Eye Research, 2003
The high content of glutathione (GSH) in the lens is believed to protect thiols in structural proteins and enzymes for proper biological functions. The lens has both biosynthetic and regenerating systems for GSH to maintain its large pool size. However, ageing lenses or lenses under oxidative stress show an extensively diminished size of GSH pool with ...
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The high content of glutathione (GSH) in the lens is believed to protect thiols in structural proteins and enzymes for proper biological functions. The lens has both biosynthetic and regenerating systems for GSH to maintain its large pool size. However, ageing lenses or lenses under oxidative stress show an extensively diminished size of GSH pool with ...
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Redox Regulation of Cellular Signalling
Cellular Signalling, 1999Extracellular stimuli elicit a variety of responses, such as cell proliferation and differentiation, through the cellular signalling system. Binding of growth factors to the respective receptor leads to the activation of receptor tyrosine kinases, which in turn stimulate downstream signalling systems such as mitogen-activated protein (MAP) kinases ...
H, Kamata, H, Hirata
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Redox Regulation of Hexokinases
Antioxidants & Redox Signaling, 2018Significance: Hexokinases are key enzymes that are responsible for the first reaction of glycolysis, but they also moonlight other cellular processes, including mitochondrial redox signaling regulation. Modulation of hexokinase activity and spatiotemporal location by reactive oxygen and nitrogen species as well ...
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Redox regulation of development and regeneration
Current Opinion in Genetics & Development, 2019Oxygen is essential to contemporary life, providing the major electron sink underlying cellular energy metabolism. In addition to providing energy, largely involving redox reactions within mitochondria, oxidative metabolism produces reactive byproducts that are damaging to cellular components.
James A, Coffman, Yi-Hsien, Su
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Redox regulation of TNF signaling
BioFactors, 1999AbstractTNF is produced during inflammation and induces, among other activities, cell death in sensitive tumour cells. We previously reported an increased generation of ROS in TNF‐treated L929 fibrosarcoma cells prior to cell death. These ROS are of mitochondrial origin and participate in the cell death process.
V, Goossens +7 more
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Redox regulation of hepatocyte apoptosis
Journal of Gastroenterology and Hepatology, 2007AbstractCell death can be regulated by the sensitivity of proteins with a functional role in death pathways to redox environment. The antioxidant glutathione (GSH) regulates cell death pathways by modulating the redox state of specific thiol residues of target proteins including transcription factors, stress kinases and caspases, which participate in ...
García-Ruiz, Carmen +1 more
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Redox Regulation of the Glucocorticoid Receptor
Antioxidants & Redox Signaling, 1999Redox regulation is currently considered as a mode of signal transduction for coordinated regulation of a variety of cellular processes. The transcriptional regulation of gene expression is also influenced by cellular redox state, most possibly through the oxido-reductive modification of transcription factors.
H, Tanaka +5 more
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Redox regulation of intercellular transport
Protoplasma, 2010Plant cells communicate with each other via plasmodesmata (PDs) in order to orchestrate specific responses to environmental and developmental cues. At the same time, environmental signals regulate this communication by promoting changes in PD structure that modify symplastic permeability and, in extreme cases, isolate damaged cells.
Yoselin, Benitez-Alfonso +2 more
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Fundamentals of redox regulation in biology
Nature Reviews Molecular Cell BiologyOxidation-reduction (redox) reactions are central to the existence of life. Reactive species of oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular processes. Yet, excessive levels of oxidants are associated with ageing and many diseases, including cardiological and neurodegenerative diseases, and cancer.
Helmut Sies +2 more
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