Results 41 to 50 of about 387,787 (305)

Data on Connexin 43 hemichannels regulation of cellular redox in lens

Data in Brief, 2021
This article describes a dataset that is related to the research paper “Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage”.
Yumeng Quan, Yu Du, Changrui Wu, Sumin Gu, Jean X. Jiang   +4 more
doaj   +1 more source

Redox proteomics of the inflammatory secretome identifies a common set of redoxins and other glutathionylated proteins released in inflammation, influenza virus infection and oxidative stress [PDF]

, 2015
Protein cysteines can form transient disulfides with glutathione (GSH), resulting in the production of glutathionylated proteins, and this process is regarded as a mechanism by which the redox state of the cell can regulate protein function. Most studies
A Erroi, A Kawakami, A Shevchenko, Anna Teresa Palamara, AT Palamara, B Beutler, B Sahaf, BA Beutler, BJ Zheng, C Lind, Christopher Horst Lillig, D Tang, DA Davis, DC Lee, DM Sullivan, E El Eter, Eva-Maria Hanschmann, F Cuello, F Martinon, F Montrichard, FJ Schweigert, FJ Staal, H Huang, H Kono, H Nakamura, H Thor, H Wang, J Cai, JE Meza, JF Andersen, JM McCord, JM Thornton, JP Brennan, JR Godoy, JR Riddell, Juan Sastre, JW Chang, K Tilleman, KR Atkuri, L Coppo, L Mullen, L Nencioni, L Nencioni, L Rossi, LA Herzenberg, Lisa Mullen, Lucas Bowler, Lucia Nencioni, M Bianchi, M Fratelli, M Fratelli, M Valko, Manuela Mengozzi, MC Lee, N Mor-Vaknin, O Takeuchi, P Checconi, P Ghezzi, P Scaffidi, Paola Checconi, Pietro Ghezzi, PJ Kersey, R Bertini, R Geiben-Lynn, R Medzhitov, R Schreck, R Sgarbanti, RC Fahey, Rossella Sgarbanti, S Klein-Scory, S Salzano, Simona Panella, Sonia Salzano, T Akaike, T Hennet, T Laragione, T Laragione, T Oda, T Shichita, TT Phung, Y Tagaya, Y Xie, YM Go   +82 more
core   +4 more sources

Quantitative analysis of NRF2 pathway reveals key elements of the regulatory circuits underlying antioxidant response and proliferation of ovarian cancer cells [PDF]

, 2014
Cells are constantly exposed to Reactive Oxygen Species (ROS) produced both endogenously to meet physiological requirements and from exogenous sources.
Bown, James, Deeni, Yusuf, Goltsov, Alexey, Harrison, David J., Khalil, Hilal S., Langdon, Simon P.   +5 more
core   +4 more sources

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells [PDF]

, 2018
Wiring metabolic signaling circuits in thymocytes Cell differentiation is often accompanied by metabolic changes. Yang et al. report that generation of double-positive (DP) thymocytes from double-negative (DN) cells coincides with dynamic regulation of ...
Awad, Walid, Blanco, Daniel Bastardo, Chen, Wenan, Chen, Xiang, Cheng, Changde, Chi, Hongbo, Dash, Pradyot, Dhungana, Yogesh, Easton, John, Guo, Xi-Zhi J., Kc, Anil, Neale, Geoffrey, Rosencrance, Celeste, Thomas, Paul G., Yang, Kai   +14 more
core   +1 more source

The basic chemistry of exercise-induced DNA oxidation:oxidative damage, redox signalling and their interplay [PDF]

, 2015
Acute exercise increases reactive oxygen and nitrogen species generation. This phenomenon is associated with two major outcomes: (1) redox signalling and (2) macromolecule damage.
Close, Graeme L., Cobley, James N., Malone, John K., Margaritelis, Nikos V., Morton, James P., Nikolaidis, Michalis G.   +5 more
core   +3 more sources

Disturbance of Response to Acute Thermal Pain in Naturally Occurring Cholecystokinin-A Receptor Gene Knockout Otsuka Long-Evans Tokushima Fatty (OLETF) Rats

Journal of Pharmacological Sciences, 2006
.: Otsuka Long-Evans Tokushima Fatty (OLETF) rats lack cholecystokinin-A receptor (CCK-AR) because of a genetic abnormality. We observed that body temperature homeostasis in response to changes in ambient temperature was deteriorated in OLETF rats, while
Miyasaka Kyoko, Nomoto Shigeki, Ohta Minoru, Kanai Setsuko, Kaneko Takao, Tahara Shoichi, Funakoshi Akihiro   +6 more
doaj   +1 more source

Proteasome Lid Bridges Mitochondrial Stress with Cdc53/Cullin1 NEDDylation Status [PDF]

, 2019
Cycles of Cdc53/Cullin1 rubylation (a.k.a NEDDylation) protect ubiquitin-E3 SCF (Skp1-Cullin1-F-box protein) complexes from self-destruction and play an important role in mediating the ubiquitination of key protein substrates involved in cell cycle ...
Bramasole, L., Gefen, E., Glickman, M. H., Gurevich, S., Jimenez-Morales, D., Johnson, J., Klein, Y., Krogan, N. J., Panat, N., Pick, E., Radzinski, M., Reichmann, D., Reis, N., Rinaldi, T., Sinha, A.   +14 more
core   +1 more source

Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes [PDF]

, 2017
Thioredoxin 1 (Trx1) is a 12-kDa oxidoreductase that catalyzes thiol-disulfide exchange reactions to reduce proteins with disulfide bonds. As such, Trx1 helps protect the heart against stresses, such as ischemia and pressure overload.
Bhat, Santosh, Chen, Yanbin, Chin, Adave, Hirabayashi, Yoko, Hirata, Tsuyoshi, Nagarajan, Narayani, Naito, Daichi, Oka, Shin-Ichi, Sadoshima, Junichi, Saito, Toshiro, Schesing, Kevin, Sciarretta, Sebastiano, Shao, Dan, Suzuki, Wataru, Yaginuma, Hiroaki, Yodoi, Junji, Zhai, Peiyong   +16 more
core   +1 more source

Redox Regulation of PTEN by Peroxiredoxins

Antioxidants, 2021
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is known as a tumor suppressor gene that is frequently mutated in numerous human cancers and inherited syndromes.
Thang Nguyen Huu, Jiyoung Park, Ying Zhang, Iha Park, Hyun Joong Yoon, Hyun Ae Woo, Seung-Rock Lee   +6 more
doaj   +1 more source

Cytosolic redox components regulate protein homeostasis via additional localisation in the mitochondrial intermembrane space [PDF]

, 2017
Oxidative protein folding is confined to the bacterial periplasm, endoplasmic reticulum and the mitochondrial intermembrane space. Maintaining a redox balance requires the presence of reductive pathways.
Cardenas-Rodriguez, Mauricio, Tokatlidis, Konstantinos   +1 more
core   +1 more source