Results 61 to 70 of about 2,590,463 (297)

Phantom Pain Reduction by Non-ionizing Electromagnetic Treatment [PDF]

, 2010
Based on our years of experience testing a technique called non-ionizing Electromagnetic-Own-Signal-Treatment (EMOST), here, we present our preliminary results for phantom pain reduction by this method under clinical circumstances.
Istvan Bokkon
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Redox-Regulation in Cancer Stem Cells

Biomedicines, 2022
Cancer stem cells (CSCs) represent a small subset of slowly dividing cells with tumor-initiating ability. They can self-renew and differentiate into all the distinct cell populations within a tumor.
Uwe Lendeckel, Carmen Wolke
doaj   +1 more source

Ybp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape [PDF]

, 2013
Peer ...
MacKenzie, Christopher G., Smith, Deborah A., MacCallum, Donna M., Erwig, Lars Peter, Morgan, Brian A., Patterson, Miranda J., Sherston, Sam, Quinn, Janet, da Silva Dantas, Alessandra, Veal, Elizabeth A.   +9 more
core   +1 more source

Quantitative analysis of redox proteome reveals oxidation-sensitive protein thiols acting in fundamental processes of developmental hematopoiesis [Elektronisk resurs]

, 2022
Fetal and adult hematopoietic stem and progenitor cells (HSPCs) are characterized by distinct redox homeostasis that may influence their differential cellular behavior in normal and malignant hematopoiesis.
Johansson, E,, Munita, R,, Jassinskaja, M,, Ciesla, M,, Guzzi, N,, Pimkova, K,, Hansson, Jenny,, Lund University., Cao Thi Ngoc, P,, Vajrychova, M,, Bellodi, C,   +10 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Regulation of Redox Signaling by Selenoproteins [PDF]

Biological Trace Element Research, 2010
The unique chemistry of oxygen has been both a resource and threat for life on Earth for at least the last 2.4 billion years. Reduction of oxygen to water allows extraction of more metabolic energy from organic fuels than is possible through anaerobic glycolysis.
Hawkes, Wayne Chris, Alkan, Zeynep
openaire   +4 more sources

Seasonal summer stress affects systemic redox homeostasis: a longitudinal marker analysis in healthy adults

Frontiers in Public Health
IntroductionAs global climate change and urbanization accelerate, summer heat waves are becoming more frequent and intense, posing an increasing threat to human health.
Hong Zhou, Hong Zhou, Hong Zhou, Jiachen Dai, Jiachen Dai, Jiachen Dai, Yuemei Zhang, Yuemei Zhang, Yuemei Zhang, Wenwen Tang, Wenwen Tang, Wenwen Tang, Yingying Ren, Yingying Ren, Yingying Ren, Xinming Zhang, Xinming Zhang, Xinming Zhang, George H. Lorimer, Hasan Bayram, Reza A. Ghilad, Junqiang Xu, Fanghua Mei, Jun Wang, Jun Wang, Jun Wang   +25 more
doaj   +1 more source

Engineered Dynamic Hydrogel Niches for the Regulation of Redox Homeostasis in Osteoporosis and Degenerative Endocrine Diseases

Gels, 2023
Osteoporosis and degenerative endocrine diseases are some of the major causes of disability in the elderly. The feedback loop in the endocrine system works to control the release of hormones and maintain the homeostasis of metabolism, thereby regulating ...
Weihao Yuan, Jiankun Xu, Na Yang, Han Wang, Jinteng Li, Mengyao Zhang, Meiling Zhu   +6 more
doaj   +1 more source