Results 51 to 60 of about 387,787 (305)
Vascular smooth muscle contraction in hypertension [PDF]
, 2018 Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia and chronic kidney disease.
Alves-Lopes, Rheure +6 more
core +1 more source
Redox Regulation of Plant Development [PDF]
Antioxidants & Redox Signaling, 2014 We provide a conceptual framework for the interactions between the cellular redox signaling hub and the phytohormone signaling network that controls plant growth and development to maximize plant productivity under stress-free situations, while limiting growth and altering development on exposure to stress.Enhanced cellular oxidation plays a key role ...
Michael J, Considine, Christine H, Foyer
openaire +2 more sources
Redox Biology, 2015 Reactive oxygen and nitrogen species (e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis.
Yuliya Mikhed +3 more
doaj +1 more source
Redox regulation of tumor suppressor PTEN in cell signaling
Redox Biology, 2020 Phosphatase and tensin homologs deleted on chromosome 10 (PTEN) is a potent tumor suppressor and often dysregulated in cancers. Cellular PTEN activity is restrained by the oxidation of active-site cysteine by reactive oxygen species (ROS).
Ying Zhang +7 more
doaj +1 more source
Redox stress defines the small artery vasculopathy of hypertension: how do we bridge the bench-to-bedside gap? [PDF]
, 2017 Although convincing experimental evidence demonstrates the importance of vascular reactive oxygen and nitrogen species (RONS), oxidative stress, and perturbed redox signaling as causative processes in the vasculopathy of hypertension, this has not ...
Liang, Mingyu +4 more
core +1 more source
Frontiers in Cellular Neuroscience, 2021 The cellular redox state, or balance between cellular oxidation and reduction reactions, serves as a vital antioxidant defence system that is linked to all important cellular activities.
Cyril Jones Jagaraj +3 more
doaj +1 more source
Ranolazine Attenuates Trastuzumab-Induced Heart Dysfunction by Modulating ROS Production [PDF]
, 2018 The ErbB2 blocker trastuzumab improves survival in oncologic patients, but can cause cardiotoxicity. The late Na+ current inhibitor ranolazine has been shown to counter experimental HF, including doxorubicin cardiotoxicity (a condition characterized by ...
Carlo G. Tocchetti +16 more
core +3 more sources
Using the heme peroxidase APEX2 to probe intracellular H2O2 flux and diffusion
Nature CommunicationsCurrently available genetically encoded H2O2 probes report on the thiol redox state of the probe, which means that they reflect the balance between probe thiol oxidation and reduction.
Mohammad Eid +4 more
doaj +1 more source
Redox Regulation of Ion Channels [PDF]
Antioxidants & Redox Signaling, 2014 Reactive oxygen species and reactive nitrogen species (ROS/RNS) are often by-products of biochemical reactions, but are increasingly recognized as important second messengers involved in regulation of distinct cellular functions. Mild and reversible oxidation of certain amino acids within protein polypeptide chains is known to precisely control the ...
Ivan, Bogeski, Barbara A, Niemeyer
openaire +2 more sources
Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]
, 2019 A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core +2 more sources