Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation. [PDF]
Organohalide chemistry underpins many industrial and agricultural processes, and a large proportion of environmental pollutants are organohalides. Nevertheless, organohalide chemistry is not exclusively of anthropogenic origin, with natural abiotic and biological processes contributing to the global halide cycle. Reductive dehalogenases are responsible
Payne KA +9 more
europepmc +4 more sources
Mimicking reductive dehalogenases for efficient electrocatalytic water dechlorination
AbstractElectrochemical technology is a robust approach to removing toxic and persistent chlorinated organic pollutants from water; however, it remains a challenge to design electrocatalysts with high activity and selectivity as elaborately as natural reductive dehalogenases.
Yuan Min +5 more
openaire +3 more sources
Regulation of reductive dehalogenase gene transcription in Dehalococcoides mccartyi. [PDF]
The remarkable capacity of the genus Dehalococcoides to dechlorinate a multitude of different chlorinated organic compounds reflects the number and diversity of genes in the genomes of Dehalococcoides species encoding reductive dehalogenase homologues ( rdh ).
Wagner A +5 more
europepmc +5 more sources
Chlorinated solvents still represent an environmental concern that requires sustainable and innovative bioremediation strategies. This study describes the microbiome composition of a novel bioelectrochemical system (BES) based on sequential reductive ...
Maria L. Di Franca +7 more
doaj +1 more source
GENETICS AND BIOCHEMISTRY OF DEHALOGENATING ENZYMES [PDF]
Microorganisms that can utilize halogenated compounds as a growth substrate generally produce enzymes whose function is carbon-halogen bond cleavage. Based on substrate range, reaction type and gene sequences, the dehalogenating enzymes can be classified
Janssen, Dick B +2 more
core +8 more sources
Guided cobamide biosynthesis for heterologous production of reductive dehalogenases [PDF]
Summary Cobamides (Cbas) are essential cofactors of reductive dehalogenases (RDases) in organohalide‐respiring bacteria (OHRB). Changes in the Cba structure can influence RDase function. Here, we report on the cofactor versatility or selectivity of Desulfitobacterium RDases ...
Torsten Schubert +8 more
openaire +3 more sources
Polyhydroxyalkanoate as a slow-release carbon source for in situ bioremediation of contaminated aquifers: from laboratory investigation to pilot-scale testing in the field [PDF]
A pilot-scale study aiming to evaluate the potential use of poly-3-hydroxy-butyrate (PHB) as an electron donor source for in situ bioremediation of chlorinated hydrocarbons in groundwater was conducted.
Alesi, Eduard +8 more
core +1 more source
Divergent roles of CprK paralogues from Desulfitobacterium hafniense in activating gene expression [PDF]
Gene duplication and horizontal gene transfer play an important role in the evolution of prokaryotic genomes. We have investigated the role of three CprK paralogues from the cAMP receptor protein-fumarate and nitrate reduction regulator (CRP-FNR) family ...
Gabor, K. +4 more
core +2 more sources
Functional Heterologous Production of Reductive Dehalogenases from Desulfitobacterium hafniense Strains [PDF]
ABSTRACT The anaerobic dehalogenation of organohalides is catalyzed by the reductive dehalogenase (RdhA) enzymes produced in phylogenetically diverse bacteria. These enzymes contain a cobamide cofactor at the active site and two iron-sulfur clusters.
Nelly, A. +4 more
openaire +3 more sources
Reductive dehalogenation has been found primarily in anaerobic communities and is originally thought to rarely occur in aerobes. A reductive dehalogenase (BhbA) was characterized from an aerobic strain of Comamonas sp.
Kai Chen, Jiandong Jiang
doaj +1 more source

