Results 71 to 80 of about 2,999 (176)

Functional Characterization of Reductive Dehalogenases by Using Blue Native Polyacrylamide Gel Electrophoresis [PDF]

Applied and Environmental Microbiology, 2013
ABSTRACT Dehalococcoides mccartyi strains are obligate organohalide-respiring bacteria harboring multiple distinct reductive dehalogenase (RDase) genes within their genomes. A major challenge is to identify substrates for the enzymes encoded by these RDase genes.
Tang, S, WW Chan, KE Fletcher, J Seifert, X Liang, FE Löffler, EA Edwards and L Adrian   +7 more
openaire   +2 more sources

Reductive dechlorination in the energy metabolism of anaerobic bacteria [PDF]

, 2017
Within the last few decades, several anaerobic bacteria have been isolated which are able to reductively dechlorinate chlorinated aliphatic and aromatic compounds at catabolic rates.
Diekert, Gabriele, Holliger, Christof, Wohlfarth, Gert   +2 more
core  

Experimental validation of in silico model-predicted isocitrate dehydrogenase and phosphomannose isomerase from Dehalococcoides mccartyi [PDF]

, 2015
Gene sequences annotated as proteins of unknown or non-specific function and hypothetical proteins account for a large fraction of most genomes. In the strictly anaerobic and organohalide respiring Dehalococcoides mccartyi, this lack of annotation ...
Edwards, Elizabeth A., Islam, M. Ahsanul, Mahadevan, Radhakrishnan, Savchenko, Alexei, Tchigvintsev, Anatoli, Yakunin, Alexander F., Yim, Veronica   +6 more
core   +2 more sources

Exploring the Potential and Evaluating Hydrocarbon Degradation by Novel Antarctic Dietzia and Pusillimonas Isolates From a Pristine Environment

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń, Julia Karbowska, Wiktoria Pietrowicz, Robert Stasiuk, Łukasz Drewniak   +4 more
wiley   +1 more source

Metagenomic- and Cultivation-Based Exploration of Anaerobic Chloroform Biotransformation in Hypersaline Sediments as Natural Source of Chloromethanes

Microorganisms, 2020
Chloroform (CF) is an environmental contaminant that can be naturally formed in various environments ranging from forest soils to salt lakes. Here we investigated CF removal potential in sediments obtained from hypersaline lakes in Western Australia ...
Peng Peng, Yue Lu, Tom N.P. Bosma, Ivonne Nijenhuis, Bart Nijsse, Sudarshan A. Shetty, Alexander Ruecker, Alexander Umanets, Javier Ramiro-Garcia, Andreas Kappler, Detmer Sipkema, Hauke Smidt, Siavash Atashgahi   +12 more
doaj   +1 more source

Selective enrichment yields robust ethene-producing dechlorinating cultures from microcosms stalled at cis-dichloroethene. [PDF]

PLoS ONE, 2014
Dehalococcoides mccartyi strains are of particular importance for bioremediation due to their unique capability of transforming perchloroethene (PCE) and trichloroethene (TCE) to non-toxic ethene, through the intermediates cis-dichloroethene (cis-DCE ...
Anca G Delgado, Dae-Wook Kang, Katherine G Nelson, Devyn Fajardo-Williams, Joseph F Miceli, Hansa Y Done, Sudeep C Popat, Rosa Krajmalnik-Brown   +7 more
doaj   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 69-106, January/February 2026.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology

Angewandte Chemie, Volume 137, Issue 28, July 7, 2025.
Targeted protein degradation (TPD) has emerged as a powerful therapeutic approach, with numerous candidates molecules now advancing into clinical development. Recent innovations have incorporated nanoparticles to facilitate and enhance these degradation processes, yielding synergistic effects.
Andrew G. Baker, Adrian Pui Ting Ho, Laura S. Itzhaki, Ljiljana Fruk   +3 more
wiley   +2 more sources

Microbial Community Changes in a Chlorinated Solvents Polluted Aquifer Over the Field Scale Treatment With Poly-3-Hydroxybutyrate as Amendment

Frontiers in Microbiology, 2018
This study investigated the organohalide-respiring bacteria (OHRB) and the supporting microbial populations operating in a pilot scale plant employing poly-3-hydroxybutyrate (PHB), a biodegradable polymer produced by bacteria from waste streams, for the ...
Bruna Matturro, Lucia Pierro, Emanuela Frascadore, Marco Petrangeli Papini, Simona Rossetti   +4 more
doaj   +1 more source

Reductive dechlorination of polychlorinated biphenyls is coupled to nitrogen fixation by a legume-rhizobium symbiosis [PDF]

, 2017
Chlorinated persistent organic pollutants, including polychlorinated biphenyls (PCBs), represent a particularly serious environmental problem and human health risk worldwide.
Christie, Peter, Luo, Yongming, Teng, Ying, Tu, Chen   +3 more
core   +1 more source