Results 61 to 70 of about 265,863 (294)

On the Analysis and Detection of Flames Withan Asynchronous Spiking Image Sensor [PDF]

open access: yes, 2018
We have investigated the capabilities of a customasynchronous spiking image sensor operating in the NearInfrared band to study flame radiation emissions, monitortheir transient activity, and detect their presence ...
Carmona Galán, Ricardo   +3 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

QRAT+: Generalizing QRAT by a More Powerful QBF Redundancy Property

open access: yes, 2018
The QRAT (quantified resolution asymmetric tautology) proof system simulates virtually all inference rules applied in state of the art quantified Boolean formula (QBF) reasoning tools.
A Biere   +19 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Correlated Component Analysis for diffuse component separation with error estimation on simulated Planck polarization data [PDF]

open access: yes, 2010
We present a data analysis pipeline for CMB polarization experiments, running from multi-frequency maps to the power spectra. We focus mainly on component separation and, for the first time, we work out the covariance matrix accounting for errors ...
Baccigalupi, C.   +8 more
core   +3 more sources

Modeling of a mobile manipulator for redundancy resolution [PDF]

open access: yesGerontechnology, 2012
Purpose Recently, various applications of robotic systems to construction sites have been tried. In this research, a mobile platform-based serial manipulator, the so called ‘mobile manipulator’, is employed for construction tasks such as material handling, beam assembly, welding, and so on. Generally, a serial manipulator has 6 DOF (degrees of freedom).
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Learning Control of Redundant DOF Robots by Optimization of Parameterized Control Space [PDF]

open access: yesModeling, Identification and Control, 1988
A framework for the learning control of robots based on a parameterized control space is doscussed. Emphasis is put on how to utilize stored motion knowledge.
Erling Lunde, Jens G. Balchen
doaj   +1 more source

Representation of acoustic communication signals by insect auditory receptor neurons [PDF]

open access: yes, 2001
Despite their simple auditory systems, some insect species recognize certain temporal aspects of acoustic stimuli with an acuity equal to that of vertebrates; however, the underlying neural mechanisms and coding schemes are only partially understood.
Herz, Andreas V. M.   +5 more
core   +2 more sources

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