Results 131 to 140 of about 5,571,829 (332)

The reference genome sequence of Artemisia argyi provides insights into secondary metabolism biosynthesis

Frontiers in Plant Science
Artemisia argyi, a perennial herb of the genus Artemisia in the family Asteraceae, holds significant importance in Chinese traditional medicine, referred to as “Aicao”. Here, we report a high-quality reference genome of Artemisia argyi L. cv. beiai, with
Xinqiang Gao, Qiang Ma, Xiaomeng Zhang, Xingyun Wang, Nuohan Wang, Yupeng Cui, Shuyan Li, Shengming Ma, Hong Wang, Kunpeng Zhang   +9 more
doaj   +1 more source

A chromosome-scale reference genome for Giardia intestinalis WB

Scientific Data, 2020
Giardia intestinalis is a protist causing diarrhea in humans. The first G. intestinalis genome, from the WB isolate, was published more than ten years ago, and has been widely used as the reference genome for Giardia research.
Feifei Xu, A. Jex, S. Svärd
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

De Novo Genome Assembly for an Endangered Lemur Using Portable Nanopore Sequencing in Rural Madagascar

Ecology and Evolution
As one of the most threatened mammalian taxa, lemurs of Madagascar are facing unprecedented anthropogenic pressures. To address conservation imperatives such as this, researchers have increasingly relied on conservation genomics to identify populations ...
Lindsey Hauff, Noa Elosmie Rasoanaivo, Andriamahery Razafindrakoto, Hajanirina Ravelonjanahary, Patricia C. Wright, Rindra Rakotoarivony, Christina M. Bergey   +6 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A high‐quality reference genome sequence of Salvia miltiorrhiza provides insights into tanshinone synthesis in its red rhizomes

The Plant Genome, 2020
Salvia miltiorrhiza Bunge, also known as red sage or Danshen, is an important traditional Chinese medicine (TCM) that has been used for thousands of years to treat cardiovascular and other diseases.
Zhenqiao Song, Caicai Lin, P. Xing, Yuan Fen, Hua Jin, Changhao Zhou, Y. Gu, Jianhua Wang, Xingfeng Li   +8 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Complete mitochondrial genomes of Culicoides brevitarsis and Culicoides imicola biting midge vectors of Bluetongue Virus

Mitochondrial DNA. Part B. Resources
Biting midges (Culicoides spp.) are important vectors of several insect borne arboviruses but are underrepresented in terms of availability of high-resolution genomic resources. We assembled and annotated complete mitochondrial genomes for two Culicoides
Khandaker Asif Ahmed, Anjana Karawita, Melissa J. Klein, Luana Fiorella Mincarelli, Barbara Secondini, Giuseppe Satta, Massimo Ancora, Cipriano Foxi, Marco Di Domenico, Michela Quaglia, Maria Goffredo, Alessio Lorusso, Cesare Cammà, Leon Court, Rahul V. Rane, Tom K. Walsh, Prasad N. Paradkar, Debbie Eagles, Gunjan Pandey, Christopher M. Hardy   +19 more
doaj   +1 more source

Construction of High-Resolution RAD-Seq Based Linkage Map, Anchoring Reference Genome, and QTL Mapping of the Sex Chromosome in the Marine Medaka Oryzias melastigma

G3: Genes, Genomes, Genetics, 2019
Medaka (Oryzias sp.) is an important fish species in ecotoxicology and considered as a model species due to its biological features including small body size and short generation time.
Bo-Young Lee, Min-Sub Kim, Beom-Soon Choi, Atsushi J. Nagano, Doris Wai Ting Au, Rudolf Shiu Sun Wu, Yusuke Takehana, Jae-Seong Lee   +7 more
doaj   +1 more source

The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins

Nature Genetics, 2020
Snakebite envenoming is a serious and neglected tropical disease that kills ~100,000 people annually. High-quality, genome-enabled comprehensive characterization of toxin genes will facilitate development of effective humanized recombinant antivenom.
Kushal Suryamohan, Sajesh P. Krishnankutty, Joseph Guillory, Matthew J. Jevit, Markus S. Schröder, Meng Wu, Boney Kuriakose, Oommen K. Mathew, R. C. Perumal, I. Koludarov, L. Goldstein, K. Senger, Mandumpala Davis Dixon, Dinesh Velayutham, Derek Vargas, Subhra Chaudhuri, Megha Muraleedharan, Ridhi Goel, Y. Chen, A. Ratan, Peter Liu, Brendan K. Faherty, Guillermo de la Rosa, H. Shibata, M. Baca, M. Sagolla, James Ziai, G. Wright, D. Vučić, Sangeetha Mohan, Aju Antony, Jeremy Stinson, D. Kirkpatrick, R. Hannoush, S. Durinck, Z. Modrusan, E. Stawiski, K. Wiley, T. Raudsepp, R. Kini, A. Zachariah, S. Seshagiri   +41 more
semanticscholar   +1 more source