Results 21 to 30 of about 5,571,829 (332)

Genomic Resources to Guide Improvement of the Shea Tree

Frontiers in Plant Science, 2021
A defining component of agroforestry parklands across Sahelo-Sudanian Africa (SSA), the shea tree (Vitellaria paradoxa) is central to sustaining local livelihoods and the farming environments of rural communities. Despite its economic and cultural value,
Iago Hale, Xiao Ma, Xiao Ma, Arthur T. O. Melo, Francis Kwame Padi, Prasad S. Hendre, Sarah B. Kingan, Shawn T. Sullivan, Shiyu Chen, Jean-Marc Boffa, Alice Muchugi, Alice Muchugi, Agyemang Danquah, Michael Teye Barnor, Ramni Jamnadass, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Allen Van Deynze, Allen Van Deynze   +20 more
doaj   +1 more source

A complete reference genome improves analysis of human genetic variation

bioRxiv, 2021
Compared to its predecessors, the Telomere-to-Telomere CHM13 genome adds nearly 200 Mbp of sequence, corrects thousands of structural errors, and unlocks the most complex regions of the human genome to clinical and functional study.
S. Aganezov, Stephanie M. Yan, Daniela C. Soto, Melanie Kirsche, Samantha Zarate, P. Avdeyev, Dylan J. Taylor, Kishwar Shafin, Alaina Shumate, Chunlin Xiao, Justin Wagner, Jennifer McDaniel, Nathan D. Olson, M. Sauria, Mitchell R. Vollger, A. Rhie, Melissa Meredith, S. Martin, Joyce Lee, S. Koren, J. Rosenfeld, B. Paten, Ryan M. Layer, Chen-Shan Chin, F. Sedlazeck, Nancy F. Hansen, Danny E. Miller, A. Phillippy, K. Miga, R. McCoy, M. Dennis, J. Zook, M. Schatz   +32 more
semanticscholar   +1 more source

Envisioning the next human genome reference [PDF]

Disease Models & Mechanisms, 2021
Summary: We provide an Editorial perspective on approaches to improve ethnic representation in the human genome reference sequence, enabling its widespread use in genomic studies and precision medicine to benefit all peoples.
Monkol Lek, Elaine R. Mardis
openaire   +3 more sources

Genomic surveillance of Acinetobacter baumannii in the Philippines, 2013–2014

Western Pacific Surveillance and Response, 2021
Objective: Acinetobacter baumannii is an opportunistic nosocomial pathogen that has increasingly become resistant to carbapenems worldwide. In the Philippines, rates of carbapenem resistance and multidrug resistance are above 50%.
Jeremiah Chilam, Silvia Argimon, Marilyn T Limas, Melissa L Masim, June M Gayeta, Marietta L Lagrada, Agnettah M Olorosa, Victoria Cohen, Lara T Hernandez, Benjamin Jeffrey, Khalil Abudahab, Charmian M Hufano, Sonia B Sia, Matthew TG Holden, John Stelling, David M Aanensen, Celia C Carlos   +16 more
doaj   +1 more source

Reference genome choice and filtering thresholds jointly influence phylogenomic analyses

bioRxiv, 2023
Molecular phylogenies are a cornerstone of modern comparative biology and are commonly employed to investigate a range of biological phenomena, such as diversification rates, patterns in trait evolution, biogeography, and community assembly.
J. Rick, Chad D. Brock, Alexander L. Lewanski, Jimena Golcher-Benavides, C. Wagner   +4 more
semanticscholar   +1 more source

Telomere-to-telomere and gap-free reference genome assembly of the kiwifruit Actinidia chinensis

Horticulture Research, 2022
Kiwifruit is an economically and nutritionally important fruit crop with extremely high contents of vitamin C. However, the previously released versions of kiwifruit genomes all have a mass of unanchored or missing regions.
Junyang Yue, Qinyao Chen, Yingzhen Wang, Lei Zhang, Cheng Ye, Xu Wang, Shuo Cao, Yunzhi Lin, Wei Huang, He Xian, H. Qin, Yanli Wang, Sijia Zhang, Yingli Wu, Songhu Wang, Yi Yue, Yongsheng Liu   +16 more
semanticscholar   +1 more source

The new bovine reference genome assembly provides new insight into genomic organization of the bovine major histocompatibility complex [PDF]

Journal of Central European Agriculture, 2019
The reference genome sequence represents a key resource for genetic studies of the target species. In 2009, two reference assemblies of the cattle (Bos taurus) genome, were published (Btau 4.0 and UMD 2.0).
Minja Zorc, Jernej Ogorevc, Peter Dovc
doaj   +1 more source

Reference genome of the leopard seal (Hydrurga leptonyx), a Southern Ocean apex predator [PDF]

Frontiers in Genetics
J. Canitz, S. S. Kienle, S. S. Kienle, K. van der Linde, R. Borras-Chavez, R. Borras-Chavez, E. S. Sperou, A. Leahy, A. Leahy, S. Rivera, S. Rivera, M. Autenrieth, J. I. Hoffman, J. I. Hoffman, J. I. Hoffman, J. I. Hoffman, J. I. Hoffman, C. A. Bonin   +17 more
doaj   +2 more sources

Improved pea reference genome and pan-genome highlight genomic features and evolutionary characteristics

Nature Genetics, 2022
Complete and accurate reference genomes and annotations provide fundamental resources for functional genomics and crop breeding. Here we report a de novo assembly and annotation of a pea cultivar ZW6 with contig N50 of 8.98 Mb, which features a 243-fold ...
T. Yang, Rong Liu, Yingfeng Luo, Songnian Hu, Dong Wang, Chenyu Wang, M. Pandey, S. Ge, Quanle Xu, Nana Li, Guan Li, Yuning Huang, R. Saxena, Yishan Ji, Mengwei Li, Xin Yan, Yu-hua He, Yujiao Liu, Xuejun Wang, Chao Xiang, R. Varshney, H. Ding, Shenghan Gao, X. Zong   +23 more
semanticscholar   +1 more source

Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies

Genome Biology, 2020
Recent long-read assemblies often exceed the quality and completeness of available reference genomes, making validation challenging. Here we present Merqury, a novel tool for reference-free assembly evaluation based on efficient k-mer set operations.
A. Rhie, B. Walenz, S. Koren, A. Phillippy   +3 more
semanticscholar   +1 more source