Results 31 to 40 of about 5,571,829 (332)

An improved ovine reference genome assembly to facilitate in-depth functional annotation of the sheep genome

open access: yesGigaScience, 2022
Background The domestic sheep (Ovis aries) is an important agricultural species raised for meat, wool, and milk across the world. A high-quality reference genome for this species enhances the ability to discover genetic mechanisms influencing biological ...
K. Davenport   +10 more
semanticscholar   +1 more source

Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines

open access: yesNature Communications, 2020
Whole-genome sequencing (WGS) can support drug resistance surveillance, but is rare in low- and middle-income countries. Here, the authors integrate WGS within the national antimicrobial resistance surveillance program in the Philippines and conduct a ...
Silvia Argimón   +23 more
doaj   +1 more source

Benchmark study for evaluating the quality of reference genomes and gene annotations in 114 species

open access: yesFrontiers in Veterinary Science, 2023
IntroductionFor reference genomes and gene annotations are key materials that can determine the limits of the molecular biology research of a species; however, systematic research on their quality assessment remains insufficient.MethodsWe collected ...
Sinwoo Park   +7 more
doaj   +1 more source

A novel canine reference genome resolves genomic architecture and uncovers transcript complexity

open access: yesCommunications Biology, 2021
We present GSD_1.0, a high-quality domestic dog reference genome with chromosome length scaffolds and contiguity increased 55-fold over CanFam3.1. Annotation with generated and existing long and short read RNA-seq, miRNA-seq and ATAC-seq, revealed that ...
Chao Wang   +17 more
semanticscholar   +1 more source

High-quality genome assembly of 'Cuiguan' pear (Pyrus pyrifolia) as a reference genome for identifying regulatory genes and epigenetic modifications responsible for bud dormancy

open access: yesHorticulture Research, 2021
Dormancy-associated MADS-box ( DAM ) genes serve as crucial regulators of the endodormancy cycle in rosaceous plants. Although pear DAM genes have been identified previously, the lack of a high-quality reference genome and techniques to study gene ...
Yuhao Gao   +10 more
semanticscholar   +1 more source

High-Quality Genomes and High-Density Genetic Map Facilitate the Identification of Genes From a Weedy Rice

open access: yesFrontiers in Plant Science, 2021
Genes have been lost or weakened from cultivated rice during rice domestication and breeding. Weedy rice (Oryza sativa f. spontanea) is usually recognized as the progeny between cultivated rice and wild rice and is also known to harbor an gene pool for ...
Fei Li   +19 more
doaj   +1 more source

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

open access: yesBMC Bioinformatics, 2011
BackgroundRNA-Seq is revolutionizing the way transcript abundances are measured. A key challenge in transcript quantification from RNA-Seq data is the handling of reads that map to multiple genes or isoforms.
Bo Li, Colin N. Dewey
semanticscholar   +1 more source

Beyond a reference genome: pangenomes and population genomics of underutilized and orphan crops for future food and nutrition security

open access: yesNew Phytologist, 2022
Summary Underutilized crops are, by definition, under‐researched compared to staple crops yet come with traits that may be especially important given climate change and the need to feed a globally increasing population.
M. Chapman, Yuqi He, Meiliang Zhou
semanticscholar   +1 more source

The zebrafish reference genome sequence and its relationship to the human genome

open access: yesNature, 2013
Zebrafish have become a popular organism for the study of vertebrate gene function. The virtually transparent embryos of this species, and the ability to accelerate genetic studies by gene knockdown or overexpression, have led to the widespread use of ...
K. Howe   +176 more
semanticscholar   +1 more source

Reference genome assemblies reveal the origin and evolution of allohexaploid oat

open access: yesNature Genetics, 2021
Common oat (Avena sativa) is an important cereal crop serving as a valuable source of forage and human food. Although reference genomes of many important crops have been generated, such work in oat has lagged behind, primarily owing to its large, repeat ...
Yuanying Peng   +32 more
semanticscholar   +1 more source

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