Results 61 to 70 of about 5,571,829 (332)
Rice, 2013 BackgroundRice research has been enabled by access to the high quality reference genome sequence generated in 2005 by the International Rice Genome Sequencing Project (IRGSP).
Y. Kawahara +22 more
semanticscholar +1 more source
Genome maps across 26 human populations reveal population-specific patterns of structural variation. [PDF]
, 2019 Large structural variants (SVs) in the human genome are difficult to detect and study by conventional sequencing technologies. With long-range genome analysis platforms, such as optical mapping, one can identify large SVs (>2 kb) across the genome in ...
Cao, Han +25 more
core +2 more sources
One reference genome is not enough [PDF]
Genome Biology, 2019 A recent study on human structural variation indicates insufficiencies and errors in the human reference genome, GRCh38, and argues for the construction of a human pan-genome.
Yang, Xiaofei +3 more
openaire +4 more sources
Aquatic Sciences and Engineering, 2023 Genomic studies have largely been accelerated by the advances of next generation sequencing technologies since the beginning of the millennium. This, in turn, has motivated the generation of more reference genome assemblies not only in model organisms ...
Münevver Oral
doaj +1 more source
hg19KIndel: ethnicity normalized human reference genome [PDF]
BMC Genomics, 2019 The most widely used human genome reference assembly hg19 harbors minor alleles at 2.18 million positions as revealed by 1000 Genome Phase 3 dataset. Although this is less than 2% of the 89 million variants reported, it has been shown that the minor alleles can result in 30% false positives in individual genomes, thus misleading and burdening ...
Harsh G. Shukla +2 more
openaire +3 more sources
The genome atlas: navigating a new era of reference genomes [PDF]
Trends in Genetics, 2021 The reference genome serves two distinct purposes within the field of genomics. First, it provides a persistent structure against which findings can be reported, allowing for universal knowledge exchange between users. Second, it reduces the computational costs and time required to process genomic data by creating a scaffold that can be relied upon by ...
Alice M, Kaye, Wyeth W, Wasserman
openaire +2 more sources
Improved maize reference genome with single-molecule technologies
Nature, 2017 Complete and accurate reference genomes and annotations provide fundamental tools for characterization of genetic and functional variation. These resources facilitate the determination of biological processes and support translation of research findings ...
Yinping Jiao +27 more
semanticscholar +1 more source
Draft Genome Sequence of the Serratia rubidaea CIP 103234T Reference Strain, a Human-Opportunistic Pathogen. [PDF]
, 2015 We provide here the first genome sequence of a Serratia rubidaea isolate, a human-opportunistic pathogen.
Bonnin, RA +4 more
core +1 more source
Automated improvement of stickleback reference genome assemblies with Lep‐Anchor software
Molecular Ecology Resources, 2021 We describe an integrative approach to improve contiguity and haploidy of a reference genome assembly and demonstrate its impact with practical examples.
M. Kivikoski +3 more
semanticscholar +1 more source
Building and Improving Reference Genome Assemblies [PDF]
Proceedings of the IEEE, 2017 A genome sequence assembly provides the foundation for studies of genotypic and phenotypic variation, genome structure, and evolution of the target organism. In the past four decades, there has been a surge of new sequencing technologies, and with these developments, computational scientists have developed new algorithms to improve genome assembly ...
Karyn Meltz Steinberg +6 more
openaire +2 more sources