Results 101 to 110 of about 4,099,878 (253)
Genome position specific priors for genomic prediction
BMC Genomics, 2012 Background The accuracy of genomic prediction is highly dependent on the size of the reference population. For small populations, including information from other populations could improve this accuracy.
Brøndum Rasmus +5 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Mutual Absolute Continuity of Multiple Priors [PDF]
This note provides a behavioral characterization of mutually absolutely continuous multiple priors.Mutual absolute continuity, Multiple ...
Larry G. Epstein, Massimo Marinacci
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Hierarchies of conditional beliefs derived from commonly known priors [PDF]
In this paper, we consider a finite set of agents with commonly known full-support priors on the fundamental space of uncertainty. Then, we show that if the hierarchies of conditional beliefs á la Battigalli and Siniscalchi (1999) are derived from these ...
Tsakas Elias
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Attitude toward information and learning under multiple priors [PDF]
This paper studies learning under multiple priors by characterizing the decision maker's attitude toward information. She is incredulous if she integrates new information with respect to only those measures that minimizes the likelihood of the new ...
André Lapied +2 more
core
Noninformative priors for the normal variance ratio
Frequentist coverage probability, Probability matching priors, Ratio of variances, Reference priors,
D. Kim, S. Kang, W. Lee
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Moment Priors for Bayesian Model Choice with Applications to Directed Acyclic Graphs [PDF]
We propose a new method for the objective comparison of two nested models based on non-local priors. More specifically, starting with a default prior under each of the two models, we construct a moment prior under the larger model, and then use the ...
Luca La Rocca, Guido Consonni
core